Výsledky vyhledávání - "MESH: Immunoglobulins"

Fcγ receptor expression on splenic macrophages in adult immune thrombocytopenia

Autor: Bernard Bonnotte, Annemieke G. Laarhoven, Kim Santegoets, Philippe Saas, Maxime Samson, Gestur Vidarsson, Sylvain Audia, Olivier Facy, Timothy R D J Radstake, Pablo Ortega-Deballon, Nona Janikashvili

Publikováno v: Clinical and Experimental Immunology
Clinical and Experimental Immunology, Wiley, 2017, 188 (2), pp.275-282. ⟨10.1111/cei.12935⟩
Clinical and Experimental Immunology, 188, 275-282
Clinical and Experimental Immunology, 188(2), 275. Wiley-Blackwell
Clinical and Experimental Immunology, 188, 2, pp. 275-282
Clinical and experimental immunology, 188(2), 275-282. Wiley-Blackwell
Clinical and Experimental Immunology, Wiley, 2017, 188 (2), pp.275-282. 〈http://onlinelibrary.wiley.com/doi/10.1111/cei.12935/abstract;jsessionid=FBA5B398503A03620104AAB3C880D684.f02t03?systemMessage=Wiley+Online+Library+%27Journal+Subscribe+%2F+Renew%27+page+will+be+down+on+Wednesday+05th+July+starting+at+08.00+EDT+%2F+13.00+BST+%2F+17.30+IST+for+up+to+75+minutes+due+to+essential+maintenance.〉. 〈10.1111/cei.12935〉

Summary Splenic macrophages play a key role in immune thrombocytopenia (ITP) pathogenesis by clearing opsonized platelets. Fcγ receptors (FcγR) participate in this phenomenon, but their expression on splenic macrophages and their modulation by trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdcb58ff87b7880a8fbd365c5a5237a6
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01556448

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The route of infection with Leptospira interrogans serovar Copenhageni affects the kinetics of bacterial dissemination and kidney colonization

Autor: Nisha Nair, Maria Gomes-Solecki, Catherine Werts, Mariana Soares Guedes

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 2020, 14 (1), pp.e0007950. ⟨10.1371/journal.pntd.0007950⟩
PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14 (1), pp.e0007950. ⟨10.1371/journal.pntd.0007950⟩
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007950 (2020)

The goal of this study was to characterize how natural routes of infection affect the kinetics of pathogenic Leptospira dissemination to blood and kidney. C3H/HeJ mice were sublethally infected with L. interrogans serovar Copenhageni FioCruz L1-130 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5785e1c49ed1ef4dd2d49623b52d792a
https://doi.org/10.1371/journal.pntd.0007950

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High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect

Autor: Medina-Cano, Daniel, Ucuncu, Ekin, Nguyen, Lam Son, Nicouleau, Michael, Lipecka, Joanna, Bizot, Jean-Charles, Thiel, Christian, Foulquier, François, Lefort, Nathalie, Faivre-Sarrailh, Catherine, Colleaux, Laurence, Guerrera, Ida Chiara, Cantagrel, Vincent

Publikováno v: eLife
eLife, eLife Sciences Publication, 2018, ⟨10.7554/eLife.38309⟩
eLife, eLife Sciences Publication, 2018, 7, ⟨10.7554/eLife.38309⟩
eLife, Vol 7 (2018)
eLife, 2018, ⟨10.7554/eLife.38309⟩
eLife, 2018, 7, ⟨10.7554/eLife.38309⟩

International audience; Proper brain development relies highly on protein N-glycosylation to sustain neuronal migration, axon guidance and synaptic physiology. Impairing the N-glycosylation pathway at early steps produces broad neurological symptoms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::627777bbb9b613cea84a194c77da8ab0
https://hal.archives-ouvertes.fr/hal-02347168

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Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice

Autor: Heng-Kuan Wong, Françoise Dantzer, Valérie Schreiber, Aurélia Noll, Bernardo Reina-San-Martin, José Yélamos, Léa Gaudot, Isabelle Robert

Publikováno v: Eur J Immunol
Eur J Immunol, 2017, 47 (4), pp.665-676. ⟨10.1002/eji.201646757⟩

To mount highly specific and adapted immune responses, B lymphocytes assemble and diversify their antibody repertoire through mechanisms involving the formation of programmed DNA damage. Immunoglobulin class switch recombination (CSR) is triggered by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3a2de51cecef0a8af35091ee7c1401
https://hal.archives-ouvertes.fr/hal-02369971

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Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

Autor: Gilles Hayem, Erwan Boedec, Tarek Boussetta, Renato C. Monteiro, Jean-Michel Goujon, Pierre Launay, Pierre Bruhns, Sanae Ben Mkaddem, Marc Benhamou, Jamel El Benna, Friederike Jönsson, Elisabetta Rossato

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2014, 124 (9), pp.3945-3959. ⟨10.1172/JCI74572⟩
Journal of Clinical Investigation, 2014, 124 (9), pp.3945-3959. ⟨10.1172/JCI74572⟩

International audience; Rheumatoid arthritis-associated (RA-associated) inflammation is mediated through the interaction between RA IgG immune complexes and IgG Fc receptors on immune cells. Polymorphisms within the gene encoding the human IgG Fc rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73a8e812d16c6dc34dddbfc4c460990
https://doi.org/10.1172/jci74572

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Guillain-Barré syndrome and cytomegalovirus infection during pregnancy

Autor: Olivier Casez, Monique Baccard-Longère, Julien Lupo, Dominique Jean, Jean Boutonnat, Raphaële Germi, Gérard Besson, Pascale Hoffmann, Patrice Morand, Carole Schwebel, Alain Rougé

Publikováno v: Journal of Clinical Virology
Journal of Clinical Virology, Elsevier, 2016, 79, pp.74-76. ⟨10.1016/j.jcv.2016.04.010⟩

International audience; Guillain-Barré syndrome (GBS) is an immune-mediated disorder which can be triggered by cytomegalovirus (CMV) infection. GBS following CMV primary infection is a rare event during pregnancy, which raises the question of matern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f32650935a2d59f244c56bb844b1433
https://hal.archives-ouvertes.fr/hal-02060010

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Nerve biopsy: requirements for diagnosis and clinical value

Autor: Jean-Michel Vallat, Laurent Magy, Benoît Funalot

Publikováno v: Acta Neuropathologica
Acta Neuropathologica, Springer Verlag, 2011, 121 (3), pp.313-26. ⟨10.1007/s00401-011-0804-4⟩

International audience; In many instances, nerve biopsy is not necessary in the diagnostic work-up of a peripheral neuropathy. However, histological examination of a tissue sample is still mandatory to show specific lesions in various conditions invo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69920551dd780857aea3b67f826e4346
https://doi.org/10.1007/s00401-011-0804-4

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Ig Synthesis and Class Switching Do Not Require the Presence of the hs4 Enhancer in the 3′ IgH Regulatory Region

Autor: Michel Cogné, Véronique Truffinet, Christelle Vincent-Fabert, Yves Denizot, Rémi Fiancette, Nadine Cogné

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩

Several studies have reported that regulatory elements located 3′ of the IgH locus (namely hs3a, hs1,2, hs3b, and hs4) might play a role during class switch recombination (CSR) and Ig synthesis. While individual deletion of hs3a or hs1,2 had no eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8412c9a14d20cc8560da8e50cdb21a
https://doi.org/10.4049/jimmunol.0900214

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