Výsledky vyhledávání - "MESH: Immunoglobulin M* / pharmacology"

IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies

Autor: Cyril Clavel, Guy Serre, Géraldine Offer, Mireille Sebbag, Lætitia Laurent, Pierre Miossec, Florence Anquetil, JL Pasquali, Ndiémé Ndongo-Thiam

Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2015, 74 (7), pp.1425-1431. ⟨10.1136/annrheumdis-2013-204543⟩

ObjectivesAnticitrullinated protein antibodies (ACPA) are specifically associated with rheumatoid arthritis (RA) and produced in inflamed synovial membranes where citrullinated fibrin, their antigenic target, is abundant. We showed that immune comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26795e3e4daf3fac3e33225e8bafbcdb
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03154842

Zobrazit plný text záznamu

IgM and IgA Rheumatoid Factors Purified from Rheumatoid Arthritis Sera Boost the Fc Receptor– and Complement-Dependent Effector Functions of the Disease-Specific Anti–Citrullinated Protein Autoantibodies

Autor: Mireille Sebbag, Géraldine Offer, Cyril Clavel, Guy Serre, Florence Anquetil

Publikováno v: Journal of Immunology
Journal of Immunology, 2015, 194 (8), pp.3664-3674. ⟨10.4049/jimmunol.1402334⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (8), pp.3664-3674. ⟨10.4049/jimmunol.1402334⟩

Rheumatoid factors (RF) and the disease-specific anti–citrullinated protein autoantibodies (ACPA) coexist in the joints of rheumatoid arthritis (RA) patients where they probably contribute to synovitis. We investigated the influence of IgM and IgA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0222e91350dcfd7af0463caaa6e39f
https://ut3-toulouseinp.hal.science/hal-03158960

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání