Výsledky vyhledávání - "MESH: Immunity, Innate / immunology"

Repositioning TH cell polarization from single cytokines to complex help

Autor: Thomas Korn, Francisco J. Quintana, Matteo Iannacone, Florent Ginhoux, Anne Dejean, Burkhard Becher, Selma Tuzlak, Ari Waisman

Publikováno v: Nature Immunology
Nature Immunology, 2021, 22 (10), pp.1210-1217. ⟨10.1038/s41590-021-01009-w⟩

International audience; When helper T (TH) cell polarization was initially described three decades ago, the TH cell universe grew dramatically. New subsets were described based on their expression of few specific cytokines. Beyond TH1 and TH2 cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1c5e3a4157d8f49697a041438addf5
https://ut3-toulouseinp.hal.science/hal-03694994

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Legionella pneumophila Effector RomA Uniquely Modifies Host Chromatin to Repress Gene Expression and Promote Intracellular Bacterial Replication

Autor: Tobias Sahr, Clement Bertholet, Carmen Buchrieser, Christophe Rusniok, Raphaël Margueron, Serena Sanulli, Monica Rolando, Laura Gomez-Valero

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩

International audience; Histone posttranslational modifications control eukaryotic gene expression and regulate many biological processes including immunity. Pathogens alter host epigenetic control to aid pathogenesis. We find that the intracellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7f9ba679975f15521adf796cc088f3

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Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells

Autor: Françoise Raynaud, Yves Lepelletier, Olivier Hermine, Réda Hadj-Slimane, Christophe Gras, Claudine Pique, Jean-Philippe Herbeuval, Lucie Barblu, Renaud Colisson

Publikováno v: Blood
Blood, American Society of Hematology, 2010, 115 (11), pp.2177-2185. ⟨10.1182/blood-2009-06-224741⟩
Blood, American Society of Hematology, 2010, 115, pp.2177-2185

A recent report demonstrated that free human T-cell leukemia virus 1 (HTLV-1) could infect plasmacytoid dendritic cells (pDCs). The major role of pDCs is to secrete massive levels of interferon-α (IFN-α) upon virus exposure; however, the induction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25de7426d0b463328339c189bc5c1cbd
https://doi.org/10.1182/blood-2009-06-224741

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Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

Autor: Nico van Rooijen, Molly A. Ingersoll, Gabriela Mora-Bau, Gwendalyn J. Randolph, Matthew L. Albert, Andrew M. Platt

Publikováno v: PLoS Pathogens, Vol 11, Iss 7, p e1005044 (2015)
PLoS Pathogens, 11(7):e1005044. Public Library of Science
PLoS Pathogens
PLoS Pathogens, 2015, 11 (7), pp.e1005044. ⟨10.1371/journal.ppat.1005044⟩
PLoS Pathogens, Public Library of Science, 2015, 11 (7), pp.e1005044. ⟨10.1371/journal.ppat.1005044⟩
Mora-Bau, G, Platt, A M, van Rooijen, N, Randolph, GJ, Albert, M L & Ingersoll, M A 2015, ' Macrophages Subvert Adaptive Immunity to Urinary Tract Infection ', PLoS Pathogens, vol. 11, no. 7, e1005044 . https://doi.org/10.1371/journal.ppat.1005044

Urinary tract infection (UTI) is one of the most common bacterial infections with frequent recurrence being a major medical challenge. Development of effective therapies has been impeded by the lack of knowledge of events leading to adaptive immunity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cf55ab23f1c76137bd24ef53271d3a
http://europepmc.org/articles/PMC4504509?pdf=render

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Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer

Autor: Cyrill A. Rentsch, George N. Thalmann, Lucie Peduto, Matthew L. Albert, Caroline Demangel, Hélène Jusforgues-Saklani, Charlotte Auriau, Alexander Bachmann, Joel R. Gsponer, Fabrice Lemaître, Frédéric D. Birkhäuser, Claire Biot, Philippe Bousso

Publikováno v: Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2012, 4 (137), pp.137ra72. ⟨10.1126/scitranslmed.3003586⟩
Science Translational Medicine, American Association for the Advancement of Science, 2012, 4 (137), pp.137ra72. 〈10.1126/scitranslmed.3003586〉
Science Translational Medicine, 2012, 4 (137), pp.137ra72. ⟨10.1126/scitranslmed.3003586⟩
Sci Transl Med

Comment in Words of wisdom. Re: Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer. [Eur Urol. 2012] Bladder cancer: Pre-existing immunity to BCG can boost clinical response to intravesical therapy. [Nat Rev Urol.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934a81401d624dce6905d1010e5deece
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402032

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Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection

Autor: Antonio Riva, Matthew L. Albert, Nikolai V. Naoumov, Roger Williams, Arvydas Ambrozaitis, Armanda Casrouge, Melissa E. Laird, Shilpa Chokshi

Publikováno v: Hepatology
Hepatology, Wiley-Blackwell, 2014, 60 (2), pp.487-496. ⟨10.1002/hep.27139⟩
Hepatology, 2014, 60 (2), pp.487-496. ⟨10.1002/hep.27139⟩

The pathogenesis of hepatitis C virus (HCV) infection is strongly influenced by the nature of the host's antiviral immunity. Counterintuitively, elevated serum concentrations of C-X-C chemokine 10 (CXCL10), a potent chemoattractant for antiviral T-ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776ea249388107e90f11a30f2413cbf5
https://pubmed.ncbi.nlm.nih.gov/24668726

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Secreted group IIA phospholipase A2 protects humans against the group B streptococcus: experimental and clinical evidence

Autor: Elin Movert, Yongzheng Wu, Thomas Areschoug, Fredrik Kahn, Gérard Lambeau, Lhousseine Touqui

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2013, 208 (12), pp.2025-2035. ⟨10.1093/infdis/jit359⟩
Journal of Infectious Diseases, 2013, 208 (12), pp.2025-2035. ⟨10.1093/infdis/jit359⟩

International audience; Group B streptococcus (GBS) is a leading neonatal pathogen and a growing cause of invasive disease in the elderly, with clinical manifestations such as pneumonia and sepsis. Despite its clinical importance, little is known abo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a69a9d61d908a3a8f23f486ff8dbda
https://pubmed.ncbi.nlm.nih.gov/23901095

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Developmental programming of natural killer and innate lymphoid cells

Autor: Christian A. J. Vosshenrich, James P. Di Santo

Publikováno v: Current Opinion in Immunology
Current Opinion in Immunology, Elsevier, 2013, ⟨10.1016/j.coi.2013.02.002⟩
Current Opinion in Immunology, 2013, ⟨10.1016/j.coi.2013.02.002⟩

International audience; In recent years we have witnessed a blooming interest in innate lymphoid cell (ILC) biology thanks to the discovery of novel lineages of ILC that are phenotypically and functionally distinct from NK cells. While the importance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc0b00a8707752b99bdd1133226810d
https://hal.archives-ouvertes.fr/hal-01406501/document

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