Identification of Paired-related Homeobox Protein 1 as a key mesenchymal transcription factor in pulmonary fibrosis

Autor: Marchal-Duval, Emmeline, Homps-Legrand, Méline, Froidure, Antoine, Jaillet, Madeleine, Ghanem, Mada, Lou, Deneuville, Justet, Aurélien, Maurac, Arnaud, Vadel, Aurelie, Fortas, Emilie, Cazes, Aurelie, Joannes, Audrey, Giersh, Laura, Mal, Herve, Mordant, Pierre, Piolot, Tristan, Truchin, Marin, Mounier, Carine, Schirduan, Ksenija, Korfei, Martina, Gunther, Andreas, Mari, Bernard, Jaschinski, Frank, Crestani, Bruno, Mailleux, Arnaud

Publikováno v: eLife, Vol. 12, no.1, p. 1-32 (2023)
eLife
eLife, 2023, 12, pp.e79840. ⟨10.7554/eLife.79840⟩

Matrix remodeling is a salient feature of idiopathic pulmonary fibrosis (IPF). Targeting cells driving matrix remodeling could be a promising avenue for IPF treatment. Analysis of transcriptomic database identified the mesenchymal transcription facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1996ed1dcf65d6fdb8ee48a755b89e39
https://hdl.handle.net/2078.1/276007

Cardiorespiratory adaptation during 6-Minute Walk Test in fibrotic idiopathic interstitial pneumonia patients who did or did not respond to pulmonary rehabilitation

Autor: Cécile Chenivesse, Jean-Marie Grosbois, Baptiste Chéhère, Benoit Wallaert, Valérie Bougault

Publikováno v: European Journal of Physical and Rehabilitation Medicine
European Journal of Physical and Rehabilitation Medicine, Edizioni Minerva Medica, 2019, 55 (1), pp.103-112. ⟨10.23736/S1973-9087.18.05093-1⟩

International audience; Background: Pulmonary rehabilitation (PR) improves performance in the 6-min walk test (6MWT) in a subset of patients with fibrotic idiopathic interstitial pneumonia (f-IIP); however, a large proportion of patients does not res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8849fc755d2a9b1317a70c8445b605d3
https://doi.org/10.23736/s1973-9087.18.05093-1

Octreotide treatment of idiopathic pulmonary fibrosis: a proof-of-concept study

Autor: Marie-Pierre Debray, Isabelle Monnet, Xavier Duval, Bruno Crestani, Benoit Wallaert, Emmanuel Bergot, Monique Dehoux, Abdellatif Tazi, J. Chapron, Dominique Israel-Biet, F. Mentré, Michel Brauner, Jacques Lacronique, Q. Dornic, Martine Reynaud-Gaubert, Philippe Delaval, Rachida Lebtahi, Michel Aubier

Publikováno v: European Respiratory Journal
European Respiratory Journal, 2012, 39 (3), pp.772-5. ⟨10.1183/09031936.00113011⟩
European Respiratory Journal, European Respiratory Society, 2012, 39 (3), pp.772-5. 〈10.1183/09031936.00113011〉
European Respiratory Journal, European Respiratory Society, 2012, 39 (3), pp.772-5. ⟨10.1183/09031936.00113011⟩

To the Editors: Idiopathic pulmonary fibrosis (IPF) is the most frequent form of idiopathic interstitial pneumonia. It is a chronic, progressive and fatal disease of unknown aetiology, characterised by histological features of usual interstitial pneu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd2ceb0bc94c989e4cf41a422f7151e
https://hal.archives-ouvertes.fr/hal-00873601

NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts

Autor: Amara, Nadia, Goven, Delphine, Prost, Fabienne, Muloway, Rachel, Crestani, Bruno, Boczkowski, Jorge

Publikováno v: Thorax
Thorax, BMJ Publishing Group, 2010, 65 (8), pp.733-8. ⟨10.1136/thx.2009.113456⟩

International audience; BACKGROUND: Persistence of myofibroblasts is believed to contribute to the development of fibrosis in idiopathic pulmonary fibrosis (IPF). Transforming growth factor beta1 (TGFbeta1) irreversibly converts fibroblasts into path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::305a40964b64aca53decb6ac483387ce
https://www.hal.inserm.fr/inserm-00515220

Composite End Points of Death and Hospitalization Are the Only Appropriate Option for Most Trials

Autor: Nicolas Girerd, Ichraq Latar

Publikováno v: Chest
Chest, American College of Chest Physicians, 2015, 147 (5), pp.e189. ⟨10.1378/chest.14-3246⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5d14b402f3646833f161a9925bbd0d
https://doi.org/10.1378/chest.14-3246