Zobrazeno 1 - 4
of 4
pro vyhledávání: '"MESH: IMP Dehydrogenase"'
Autor:
Gilles Labesse, Olivier Helynck, Sophie Vichier-Guerre, Thomas Alexandre, Muriel Gelin, Hélène Munier-Lehmann, Alexandru Lupan, Laurence Dugué, Ahmed Haouz
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2019, 167, pp.124-132. ⟨10.1016/j.ejmech.2019.01.064⟩
European Journal of Medicinal Chemistry, Elsevier, 2019, 167, pp.124-132. ⟨10.1016/j.ejmech.2019.01.064⟩
European Journal of Medicinal Chemistry, 2019, 167, pp.124-132. ⟨10.1016/j.ejmech.2019.01.064⟩
European Journal of Medicinal Chemistry, Elsevier, 2019, 167, pp.124-132. ⟨10.1016/j.ejmech.2019.01.064⟩
International audience; Inosine-5'-monophosphate dehydrogenase (IMPDH) is an essential enzyme in many bacterial pathogens and is considered as a potential drug target for the development of new antibacterial agents. Our recent work has revealed the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bef6868bbbe746ea71fc1bb58c79ad2
https://hal-pasteur.archives-ouvertes.fr/pasteur-02125232/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-02125232/document
Autor:
Nicolas Picard, Pierre Marquet
Publikováno v:
Expert Opinion on Drug Metabolism and Toxicology
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2011, 7 (6), pp.731-43. ⟨10.1517/17425255.2011.570260⟩
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2011, 7 (6), pp.731-43. ⟨10.1517/17425255.2011.570260⟩
International audience; INTRODUCTION: Immunosuppressive drugs have a narrow therapeutic range and large inter-individual response variability. This has prompted pharmacogenetic studies, mostly with regard to their dose-concentration relationships, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff6bdbec013c84be1c6ebf26af4f4cc
https://www.hal.inserm.fr/inserm-00577136
https://www.hal.inserm.fr/inserm-00577136
Publikováno v:
Microbiology
Microbiology, Microbiology Society, 2008, 154 (Pt 9), pp.2629-40. ⟨10.1099/mic.0.2008/018184-0⟩
Microbiology, Microbiology Society, 2008, 154 (Pt 9), pp.2629-40. ⟨10.1099/mic.0.2008/018184-0⟩
International audience; Lactobacillus plantarum susbp. plantarum is a capnophilic Gram-positive heterotroph with optimal growth in 4 % CO(2)-enriched air. At low inorganic carbon (C(i)) concentrations, the pyr genes encoding the enzymes of the pyrimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be223034ad0b2315f18e4762087cb3c2
https://pubmed.ncbi.nlm.nih.gov/18757797
https://pubmed.ncbi.nlm.nih.gov/18757797
Autor:
Fabrice Morel, Christophe Nicolas-Nicolaz, Elise Petit, Hanane Akhdar, Sophie Langouët, André Guillouzo
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, Elsevier, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
International audience; Thiopurines (azathioprine, 6-mercaptopurine and 6-thioguanine) are therapeutic compounds widely administered in the clinic for their multiple uses (autoimmune diseases, post-transplant immunosuppression and cancer). Despite th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574eb2995e9d23f3db79666c85e57d5
https://pubmed.ncbi.nlm.nih.gov/18222062
https://pubmed.ncbi.nlm.nih.gov/18222062