Zobrazeno 1 - 10
of 33
pro vyhledávání: '"MESH: I-kappa B Kinase"'
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
Autor:
Jean-Yves Tinevez, Emmanuel Laplantine, Alain Israël, Nadine Tarantino, Bertrand Boisson, Fabrice Agou, Musa M. Mhlanga, Ricardo Henriques, Elizabeth Faris Crowell
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2014, 204 (2), pp.231-45. ⟨10.1083/jcb.201307172⟩
The Journal of Cell Biology
Journal of Cell Biology, 2014, 204 (2), pp.231-45. ⟨10.1083/jcb.201307172⟩
Journal of Cell Biology, Rockefeller University Press, 2014, 204 (2), pp.231-45. ⟨10.1083/jcb.201307172⟩
The Journal of Cell Biology
Journal of Cell Biology, 2014, 204 (2), pp.231-45. ⟨10.1083/jcb.201307172⟩
The mechanism of NEMO recruitment into supramolecular complexes and its dependence on ubiquitination differs in response to the proinflammatory cytokines TNF and IL-1.
Nuclear factor κB (NF-κB) essential modulator (NEMO), a regulatory componen
Nuclear factor κB (NF-κB) essential modulator (NEMO), a regulatory componen
Autor:
Réjane Paumelle, Sébastien Fleury, Emmanuel Bouchaert, Jonathan Vanhoutte, Céline Cudejko, Giulia Chinetti-Gbaguidi, Bart Staels, Anne Tailleux, Sarah Anissa Hannou, Patrick Rémy, Lucía Fuentes, Kadiombo Bantubungi, Kristiaan Wouters, David Dombrowicz, Charlotte Paquet
Publikováno v:
Blood
Blood, American Society of Hematology, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩
Blood, 118(9), 2556-66. The American Society of Hematology
Blood, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩
Blood, American Society of Hematology, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩
Blood, 118(9), 2556-66. The American Society of Hematology
Blood, 2011, 118 (9), pp.2556-66. ⟨10.1182/blood-2010-10-313106⟩
The CDKN2A locus, which contains the tumor suppressor gene p16INK4a, is associated with an increased risk of age-related inflammatory diseases, such as cardiovascular disease and type 2 diabetes, in which macrophages play a crucial role. Monocytes ca
Autor:
Jacques Pouysségur, Jian Dong Li, Gilles Pagès, Unhwan Ha, Hirofumi Jono, Richard Malley, Jae Hyang Lim, Tomoaki Koga, Amit Kumar Srivastava
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (3), pp.1736-47
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (3), pp.1736-47
Epithelial cells represent the first line of host innate defense against invading microbes by elaborating a range of molecules involved in pathogen clearance. In particular, epithelial mucins facilitate the mucociliary clearance by physically trappin
Autor:
Edurne Berra, Paul N. Moynagh, Jacques Pouysségur, Cormac T. Taylor, Amandine Ginouvès, Katrina M. Comerford, Kathleen T. Fitzgerald, Jens Erik Nielsen, Catherine Godson, Fergal Seeballuck, Eoin P. Cummins
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (48), pp.18154-9. ⟨10.1073/pnas.0602235103⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (48), pp.18154-9. ⟨10.1073/pnas.0602235103⟩
Hypoxia is a feature of the microenvironment of a growing tumor. The transcription factor NFkappaB is activated in hypoxia, an event that has significant implications for tumor progression. Here, we demonstrate that hypoxia activates NFkappaB through
Autor:
Fabrice Agou, Alain Israël, Hélène Sebban, Alain Chaffotte, Michel Véron, Emilie Vinolo, Gilles Courtois
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 281 (10), pp.6334-48. ⟨10.1074/jbc.M510118200⟩
Journal of Biological Chemistry, 2007, 281 (10), pp.6334-48. ⟨10.1074/jbc.M510118200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 281 (10), pp.6334-48. ⟨10.1074/jbc.M510118200⟩
Journal of Biological Chemistry, 2007, 281 (10), pp.6334-48. ⟨10.1074/jbc.M510118200⟩
The NEMO (NF-kappaB essential modulator) protein plays a crucial role in the canonical NF-kappaB pathway as the regulatory component of the IKK (IkappaB kinase) complex. The human disease anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID)
Autor:
Renate Knaup, Thomas Krieg, Pierre Chambon, Doreen Markur, Daniel Metzger, Ruth Pofahl, Manolis Pasparakis, Athanasios Stratis, Ingo Haase
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2006, 126 (3), pp.614-20. ⟨10.1038/sj.jid.5700092⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2006, 126 (3), pp.614-20. ⟨10.1038/sj.jid.5700092⟩
International audience; Skin inflammation is a complex process that involves interactions between various cell types residing in different skin compartments. Using mice with conditionally targeted I kappa B kinase 2 (IKK2) alleles, we have previously
Autor:
Alain Israël, Gilles Courtois, Shoji Yamaoka, Emilie Vinolo, François Traincard, Fabrice Agou, Michel Véron
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2004, 279 (27), pp.27861-27869. ⟨10.1074/jbc.M314278200⟩
Journal of Biological Chemistry, 2004, 279 (27), pp.27861-27869. ⟨10.1074/jbc.M314278200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2004, 279 (27), pp.27861-27869. ⟨10.1074/jbc.M314278200⟩
Journal of Biological Chemistry, 2004, 279 (27), pp.27861-27869. ⟨10.1074/jbc.M314278200⟩
International audience; NEMO (NF-κB essential modulator) plays a key role in the canonical NF-κB pathway as the scaffold/regulatory component of the IκB kinase (IKK) complex. The self-association of NEMO involves the C-terminal halves of the polyp
Autor:
Edith Puchelle, Jacky Jacquot, Caroline Majer-Teboul, Daniel Dusser, Sandie Escotte, Olivier Tabary
Publikováno v:
European Respiratory Journal
European Respiratory Journal, European Respiratory Society, 2003, 21 (4), pp.574-81
European Respiratory Journal, European Respiratory Society, 2003, 21 (4), pp.574-81
FREE FULL TEXT http://erj.ersjournals.com/cgi/content/full/21/4/574; Inhaled fluticasone propionate (FP) is widely used to reduce pulmonary inflammation in chronic obstructive pulmonary disease, but the potential effects of FP on airway epithelial ce
Autor:
Rainer Döffinger, Asma Smahi, Marion C. Bonnet, Gerd Horneff, Francesco Novelli, Anne Durandy, Volker Wahn, Tim Niehues, Jacqueline Feinberg, Janine Reichenbach, Cheng-Lung Ku, Ludovic de Beaucoudrey, Anne Puel, Jacinta Bustamante, Alain Israël, Orchidée Filipe-Santos, Jean-Laurent Casanova
Publikováno v:
Am J Hum Genet
Am J Hum Genet, 2006, 78 (4), pp.691-701. 〈10.1086/501532〉
American Journal of Human Genetics
American Journal of Human Genetics, 2006, 78 (4), pp.691-701. ⟨10.1086/501532⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2006, 78 (4), pp.691-701. ⟨10.1086/501532⟩
Am J Hum Genet, 2006, 78 (4), pp.691-701. 〈10.1086/501532〉
American Journal of Human Genetics
American Journal of Human Genetics, 2006, 78 (4), pp.691-701. ⟨10.1086/501532⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2006, 78 (4), pp.691-701. ⟨10.1086/501532⟩
International audience; Amorphic mutations in the NF- kappa B essential modulator (NEMO) cause X-dominant incontinentia pigmenti, which is lethal in males in utero, whereas hypomorphic mutations cause X-recessive anhidrotic ectodermal dysplasia with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df47363d6ac727defd5e856fa6be273e
http://www.hal.inserm.fr/inserm-00142391
http://www.hal.inserm.fr/inserm-00142391
Autor:
Anne Durandy, Guillaume Vogt, Ludovic de Beaucoudrey, Cheng-Lung Ku, Anne Puel, Jalel Chemli, Necil Kutukculer, Emilie Vinolo, Claire Fieschi, Christine Bodemer, Alessandro Plebani, Karin Christel, Brigitte Senechal, Laurent Abel, David M. Frucht, Klaus Magdorf, Capucine Picard, Michel Veron, Ariane Chapgier, Meriem Garfa, Horst von Bernuth, Ridha Barbouche, Maria Tsolia, Emmanuelle Jouanguy, Margje H. Haverkamp, Alain Israël, Jacinta Bustamante, Fabrice Agou, Maike Knackstedt, Frederic Geissmann, Steven M. Holland, Jacqueline Feinberg, Jean-Laurent Casanova, Luigi D. Notarangelo, Orchidée Filipe-Santos, Mohamed Bejaoui, Dominique Gendrel
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2010, 203 (7), pp.1745-59. ⟨10.1084/jem.20060085⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2010, 203 (7), pp.1745-59. ⟨10.1084/jem.20060085⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2010, 203 (7), pp.1745-59. 〈10.1084/jem.20060085〉
Journal of Experimental Medicine, 2010, 203 (7), pp.1745-59. ⟨10.1084/jem.20060085⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2010, 203 (7), pp.1745-59. ⟨10.1084/jem.20060085⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2010, 203 (7), pp.1745-59. 〈10.1084/jem.20060085〉
WOS: 000238940500017
PubMed ID: 16818673
Germline mutations in five autosomal genes involved in interleukin (IL)-12-dependent, interferon (IFN)-gamma-mediated immunity cause Mendelian susceptibility to mycobacterial diseases (MSMD). The mol
PubMed ID: 16818673
Germline mutations in five autosomal genes involved in interleukin (IL)-12-dependent, interferon (IFN)-gamma-mediated immunity cause Mendelian susceptibility to mycobacterial diseases (MSMD). The mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56668a2722c04a4d79bdf8c6a1587fab
https://hdl.handle.net/11454/38474
https://hdl.handle.net/11454/38474