Výsledky vyhledávání - "MESH: Hyperinsulinism"

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Adipose TriGlyceride Lipase (ATGL) and Hormone-Sensitive Lipase (HSL) protein expression is decreased in the obese insulin resistant state

Autor: Carine Valle, Egbert F. Smit, Ellen E. Blaak, Peter Arner, Wim H. M. Saris, Johan W. E. Jocken, Dominique Langin, Cecilia Holm, Gabby B. Hul

Publikováno v: Journal of Clinical Endocrinology & Metabolism, 29(6), 2292-2299. Oxford University Press
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2007, 92 (6), pp.2292-9. ⟨10.1210/jc.2006-1318⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2007, 92 (6), pp.2292-9. ⟨10.1210/jc.2006-1318⟩

International audience; AIM/HYPOTHESIS: Obesity is associated with increased triacylglycerol (TAG) storage in adipose tissue and insulin resistance. The mobilization of stored TAG is mediated by hormone-sensitive lipase (HSL) and the recently discove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba2503dbbcb591f78645ccdc8582b7d
https://doi.org/10.1210/jc.2006-1318

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Apelin, a Newly Identified Adipokine Up-Regulated by Insulin and Obesity

Autor: Charlotte Guigné, Philippe Valet, Anne Mazzucotelli, Jeremie Boucher, Bernard Masri, Danièle Daviaud, Ivan Tack, Christian Carpéné, Bernard Knibiehler, Jean-Sébastien Saulnier-Blache, Isabelle Castan-Laurell, Yves Audigier, Stephane Gesta

Publikováno v: Endocrinology
Endocrinology, 2005, 146 (4), pp.1764-71. ⟨10.1210/en.2004-1427⟩

The results presented herein demonstrate that apelin is expressed and secreted by both human and mouse adipocytes. Apelin mRNA levels in isolated adipocytes are close to other cell types present in white adipose tissue or other organs known to expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae03319e87da41a331694de86ffb2250
https://doi.org/10.1210/en.2004-1427

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Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat

Autor: Christine Rouault, René Gross, Michel Derouet, Céline Cruciani-Guglielmacci, Gérard Reach, M. Manteghetti, Mohammed Taouis, Pierre Petit, Gérard Ribes, Vincent Breil, Christophe Broca, Salwa W. Rizkalla, Bernard Pau, Alain Ktorza

Publikováno v: AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, American Physiological Society, 2004, 287, pp.E463-E471
AJP-Endocrinology and Metabolism, American Physiological Society, 2004, 287 (3), pp.E463-E471. ⟨10.1152/ajpendo.00163.2003⟩
AJP-Endocrinology and Metabolism, 2004, 287 (3), pp.E463-E471. ⟨10.1152/ajpendo.00163.2003⟩
American Journal of Physiology. Endocrinology and Metabolism (287), E463-E471. (2004)

International audience; ID-1101 (4-hydroxyisoleucine), an amino acid extracted from fenugreek seeds, exhibits an interesting glucose-dependent insulin-stimulating activity. The present study was undertaken to investigate a possible extrapancreatic ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5c4a1d5efb6bf3d27ebacdb08c3fa7
https://doi.org/10.1152/ajpendo.00163.2003

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Diabetes mellitus, hyperglycaemia and cancer

Autor: Simon, Dominique, Balkau, Beverley

Publikováno v: Diabetes & Metabolism
Diabetes & Metabolism, Elsevier Masson, 2010, 36 (3), pp.182-91. ⟨10.1016/j.diabet.2010.04.001⟩

31 pages; International audience; A moderate increase in cancer risk has been shown in diabetic patients and in individuals with abnormal glucose tolerance, mainly for digestive sites, independently of obesity, with in contrast, a protective effect f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::f61d75fb10a7d1602e1f26032b592308
https://www.hal.inserm.fr/inserm-00555021/document

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Diabetes mellitus, hyperglycaemia and cancer.: Diabetes and cancer

Autor: B. Balkau, Dominique Simon

Publikováno v: Diabetes and Metabolism
Diabetes and Metabolism, Elsevier Masson, 2010, 36 (3), pp.182-91. ⟨10.1016/j.diabet.2010.04.001⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72058b9f2ada595ef20946379717648b
https://www.hal.inserm.fr/inserm-00555021/document

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The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element-Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway

Autor: Etienne Lefai, Hubert Vidal, Sophie Rome, Rémi Rabasa-Lhoret, Jennifer Rieusset, Marie-Paule Gustin, Catherine Cerutti, Emmanuelle Meugnier, Emmanuel Disse, Aurélie Granjon, Christian Z. Paultre, Isabelle Güller, Martine Laville

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2009, 58 (11), pp.2555-2564
Diabetes, 2009, 58 (11), pp.2555-64. ⟨10.2337/db09-0165⟩
Diabetes, American Diabetes Association, 2009, 58 (11), pp.2555-64. ⟨10.2337/db09-0165⟩

OBJECTIVE Factors governing microRNA expressions in response to changes of cellular environment are still largely unknown. Our aim was to determine whether insulin, the major hormone controlling whole-body energy homeostasis, is involved in the regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f505ea7608dc44647cbdf7631c48ad2a
https://hal.archives-ouvertes.fr/hal-01982029

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Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure

Autor: Eric Sabatier, Luc Pénicaud, Afifa Ait-Belgnaoui, Aurélie Waget, Alexandre Benani, Natacha Godet, Sophie Rastrelli, Rémy Burcelin, Marc Uldry, Claude Knauf, Cendrine Cabou, Philippe Valet, André Colom, Cédric Dray, Patrice D. Cani

Publikováno v: Endocrinology
Endocrinology, 2008, 149 (10), pp.4768-77. ⟨10.1210/en.2008-0180⟩
Endocrinology, Endocrine Society, 2008, 149 (10), pp.4768-77. ⟨10.1210/en.2008-0180⟩

International audience; Glucagon-like peptide-1 (GLP-1) is a peptide released by the intestine and the brain. We previously demonstrated that brain GLP-1 increases glucose-dependent hyperinsulinemia and insulin resistance. These two features are majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d35e4ab44bcf16616dca83b31e34a14
https://www.hal.inserm.fr/inserm-00409099

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Quantification of liver perfusion with [(15)O]H(2)O-PET and its relationship with glucose metabolism and substrate levels

Autor: Slimani, Lotfi, Kudomi, Nobuyuki, Oikonen, Vesa, Jarvisalo, Mikko, Kiss, Jan, Naum, Alexandru, Borra, Ronald, Viljanen, Antti, Sipila, Hannu, Ferrannini, Ele, Savunen, Timo, Nuutila, Pirjo, Iozzo, Patricia

Publikováno v: Journal of Hepatology
Journal of Hepatology, 2008, 48 (6), pp.974-82. ⟨10.1016/j.jhep.2008.01.029⟩

International audience; BACKGROUND/AIMS: Hepatic perfusion plays an important role in liver physiology and disease. This study was undertaken to (a) validate the use of Positron Emission Tomography (PET) and oxygen-15-labeled water ([(15)O]H(2)O) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::0fa34ee95492b047c996a0f859c862fd
https://doi.org/10.1016/j.jhep.2008.01.029

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High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery

Autor: Karine Couturier, P. Gachon, D. Gonsolin, Roland Favier, Yves Boirie, Sébastien Peltier, Luc Demaison, Valérie Novel-Chaté, Salvatore Pepe, Christiane Keriel, Xavier Leverve, Stéphanie Rondel, Patrice Faure, Blandine Garait

Publikováno v: Molecular and Cellular Biochemistry
Molecular and Cellular Biochemistry, Springer Verlag, 2007, 295 (1-2), pp.217-28. ⟨10.1007/s11010-006-9291-7⟩

International audience; Although the causal relationship between insulin resistance (IR) and hypertension is not fully resolved, the importance of IR in cardiovascular dysfunction is recognized. As IR may follow excess sucrose or fructose diet, the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3957b64d49929f448081f3cab29a188
https://www.hal.inserm.fr/inserm-00388701

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