Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE−/− Mice

Autor: Vincent Sarrazy, Sophie Giorgetti-Peraldi, Laurent Yvan-Charvet, Darryl C. De Vivo, Stoyan Ivanov, Edward B. Thorp, Manon Viaud, Emmanuel L. Gautier, Marit Westerterp, Rodolphe Guinamard

Publikováno v: Circulation Research
Circulation Research, 2016, 118 (7), pp.1062-1077. ⟨10.1161/CIRCRESAHA.115.307599⟩
Circulation Research, American Heart Association, 2016, 118 (7), pp.1062-1077. ⟨10.1161/circresaha.115.307599⟩
Circulation research, 118(7), 1062-1077. LIPPINCOTT WILLIAMS & WILKINS

Rationale: Inflamed atherosclerotic plaques can be visualized by noninvasive positron emission and computed tomographic imaging with 18 F-fluorodeoxyglucose, a glucose analog, but the underlying mechanisms are poorly understood. Objective: Here, we d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526462fd8c30518bac6341c8c0df880
https://europepmc.org/articles/PMC4824305/

Combined Deletion of Macrophage ABCA1 and ABCG1 Leads to Massive Lipid Accumulation in Tissue Macrophages and Distinct Atherosclerosis at Relatively Low Plasma Cholesterol Levels

Autor: Menno Hoekstra, Illiana Meurs, Giovanna Chimini, Theo J.C. Van Berkel, Vivian de Waard, Miranda Van Eck, Ruud Out, Yanan Wang, Kim L. L. Habets, Johan Kuiper, Reeni B. Hildebrand

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2008, 28 (2), pp.258-64. ⟨10.1161/ATVBAHA.107.156935⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008, 28 (2), pp.258-64. ⟨10.1161/ATVBAHA.107.156935⟩

Objective— The purpose of this study was to evaluate the effect of the combined deletion of ABCA1 and ABCG1 expression in macrophages on foam cell formation and atherosclerosis. Methods and Results— LDL receptor knockout (KO) mice were transplant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cfdb28a3c82eb511c7cb08d2308188
https://doi.org/10.1161/atvbaha.107.156935

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

Autor: Debette, Stéphanie, Kamatani, Yoichiro, Wolf, Christiane, Agabiti Rosei, Enrico, Lanfranconi, Silvia, Ferrarese, Carlo, Susani, Emanuela, Bicocca, Milano, Giacalone, Giacomo, Paolucci, Stefano, Palmirotta, Raffaele, Paciaroni, Maurizio, Ballabio, Elena, Dittrich, Ralf, Parati, Eugenio A, Ciusani, Emilio, Fluri, Felix, Hatz, Florian, Gisler, Dominique, Amort, Margareth, Bevan, Steve, James, Tom, Olsson, Sandra, Holmegaard, Lukas, Touzé, Emmanuel, Altintas, Ayse, Martin, Juan José, Kittner, Steven, MItchell, Braxton, Stine, Colin, O'Connell, Jeff, Dueker, Nicole, Koudstaal, Peter J, de Lau, Lonneke M L, Hofman, Albert, Southerland, Andrew M, Verhaaren, Benjamin F, Uitterlinden, Andre G, Montaner, Joan, Mendioroz, Maite, Yadav, Sunaina, Khan, Muhammad Saleem, Wilder, Michael, van Dijk, Ewoud, Maaijwee, Noortje, Rutten-Jacobs, Loes, Samson, Yves, Kramer, Jamie, Malik, Shaneela, Brott, Thomas G, Brown, Robert D, Singleton, Andrew, Hardy, John, Rich, Stephen S, Tanislav, Christian, Jungehülsing, Jan, Abboud, Shérine, Béjot, Yannick, Caso, Valeria, Bersano, Anna, Gschwendtner, Andreas, Metso, Tiina M, Sessa, Maria, Cole, John, Lamy, Chantal, Medeiros, Elisabeth, Beretta, Simone, Bonati, Leo H, Grau, Armin J, Michel, Patrik, Majersik, Jennifer J, Sharma, Pankaj, Kloss, Manja, Kalashnikova, Ludmila, Nazarova, Maria, Dobrynina, Larisa, Bartels, Eva, Guillon, Benoit, van den Herik, Evita G, Fernandez-Cadenas, Israel, Jood, Katarina, Nalls, Michael A, De Leeuw, Frank-Erik, Chauhan, Ganesh, Jern, Christina, Cheng, Yu-Ching, Werner, Inge, Metso, Antti J, Lichy, Christoph, Lyrer, Philippe A, Brandt, Tobias, Boncoraglio, Giorgio B, Wichmann, Heinz-Erich, Gieger, Christian, Engelter, Stefan T, Johnson, Andrew D, Böttcher, Thomas, Castellano, Maurizio, Arveiler, Dominique, Ikram, M Arfan, Breteler, Monique M B, Padovani, Alessandro, Meschia, James F, Kuhlenbäumer, Gregor, Rolfs, Arndt, Pezzini, Alessandro, Worrall, Bradford B, Consortium, International Stroke Genetics, Ringelstein, Erich-Bernd, Zelenika, Diana, Tatlisumak, Turgut, Lathrop, Mark, Leys, Didier, Amouyel, Philippe, Dallongeville, Jean, Group, CADISP, Thijs, Vincent, Lemmens, Robin, Pandolfo, Massimo, Bodenant, Marie, Louillet, Fabien, Mas, Jean-Louis, Deltour, Sandrine, Leder, Sara, Léger, Anne, Canaple, Sandrine, Godefroy, Olivier, Markus, Hugh S, Giroud, Maurice, Jacquin, Agnès, Moulin, Thierry, Vullier, Fabrice, Tzourio, Christophe, Dos Santos, Michael, Malik, Rainer, Hausser, Ingrid, Thomas-Feles, Constanze, Weber, Ralf, Dichgans, Martin, Grond-Ginsbach, Caspar, Hacke, Werner, Giossi, Alessia, Volonghi, Irene, Costa, Paolo, del Zotto, Elisabetta, Morotti, Andrea, Poli, Loris, Lorenza Muiesan, Maria, Salvetti, Massimo

Publikováno v: Nature Genetics
Nature Genetics, 2014, 47 (1), pp.78-83. ⟨10.1038/ng.3154⟩
Nature Genetics, Nature Publishing Group, 2014, 47 (1), pp.78-83. ⟨10.1038/ng.3154⟩
Nature Genetics, 47, 1, pp. 78-83
Nature genetics 47(1), 78-83 (2014). doi:10.1038/ng.3154
Nature Genetics, 47(1), 78-83. Nature Publishing Group
Nature Genetics, 47, 78-83

Item does not contain fulltext Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a major cause of ischemic stroke in young adults although relatively uncommon in the general population (incidence of 2.6/100,000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bac65b9d6cd93bd08fc469129ce5e3e
https://doi.org/10.1038/ng.3154

Alteration of plasmalemmal caveolae mimics endothelial dysfunction observed in atheromatous rabbit aorta

Autor: Marie-José Fouque, Marc Poirot, Francis Bayard, Jacques Rami, Dominique Caillaud, Benoit Darblade, Jean-François Arnal, Jean-Claude Thiers

Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2001, 50, pp.566-76
Cardiovascular Research, 2001, 50, pp.566-76

OBJECTIVE: In endothelial cells, nitric oxide (NO) is produced by the endothelial isoform of nitric oxide synthase (eNOS), which is localized in the cholesterol-rich plasmalemmal microdomains involved in signal transduction, known as caveolae. The pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024a141213e0e1cf9a6e51f863dca45f
https://doi.org/10.1016/s0008-6363(01)00251-6

p-Cresyl sulfate promotes insulin resistance associated with CKD

Autor: Laetitia Koppe, Raymond Vanholder, Christophe O. Soulage, Caroline C. Pelletier, Ziad A. Massy, Stéphane Chambert, Roxane E. Vella, Yann Dugenet, Nicolas J. Pillon, Hédi Soula, Denis Fouque, Marine L. Croze, Griet Glorieux

Publikováno v: Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, 2013, 24 (1), pp.88-99. ⟨10.1681/ASN.2012050503⟩
Journal of the American Society of Nephrology, 2013, 24 (1), pp.88-99. ⟨10.1681/ASN.2012050503⟩

International audience; The mechanisms underlying the insulin resistance that frequently accompanies CKD are poorly understood, but the retention of renally excreted compounds may play a role. One such compound is p-cresyl sulfate (PCS), a protein-bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0220b7a972942551f2e98e4eaf9b01
https://hal.inria.fr/hal-00850482