7α-Hydroxy-Dehydroepiandrosterone and Immune Response

Autor: V Chmielewski, Pierre Lafaye, Denis Pompon, Farida Nato, Robert Morfin, Anne-Cécile Cotillon

Publikováno v: Annals of the New York Academy of Sciences
Annals of the New York Academy of Sciences, Wiley, 2000, 917 (1), pp.971-982. ⟨10.1111/j.1749-6632.2000.tb05464.x⟩
Annals of the New York Academy of Sciences, 2000, 917 (1), pp.971-982. ⟨10.1111/j.1749-6632.2000.tb05464.x⟩

International audience; In human and murine lymphoid organs, circulating 3 beta-hydroxysteroids, including pregnenolone (PREG), dehydroepiandrosterone (DHEA), and epiandrosterone (EPIA), are 7 alpha-hydroxylated by a cytochrome P450 identified in the

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