Výsledky vyhledávání - "MESH: Hydrazines"

A novel aryl-hydrazide from the marine lichen Lichina pygmaea: isolation, synthesis of derivatives, and cytotoxicity assays

Autor: Françoise Lohézic-Le Dévéhat, Catherine Roullier, Marylène Chollet-Krugler, Joël Boustie, Pierre van de Weghe

Publikováno v: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, 2010, 20 (15), pp.4582-6. ⟨10.1016/j.bmcl.2010.06.013⟩
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2010, 20 (15), pp.4582-6. ⟨10.1016/j.bmcl.2010.06.013⟩

International audience; A new aryl-hydrazide l-glutamic acid derivative, pygmeine (3), was isolated from a methanolic extract of Lichina pygmaea, a marine lichen. Synthetic derivatives obtained via a two-step coupling of l-glutamic acid with phenylhy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c96311375021ddadc2c33a2033ccd67
https://hal.science/hal-00844454

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Carbonyl scavenger and antiatherogenic effects of hydrazine derivatives

Autor: Sylvain Galvani, Marie-Hélène Grazide, Robert Salvayre, Michel Baltas, Angelo Parini, Lionel Rostaing, Koji Uchida, Christelle Coatrieux, Meyer Elbaz, Jean-Claude Thiers, Anne Nègre-Salvayre, Nassim Kamar

Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, 2008, 45 (10), pp.1457-67. ⟨10.1016/j.freeradbiomed.2008.08.026⟩
Free Radical Biology and Medicine, Elsevier, 2008, 45 (10), pp.1457-67. ⟨10.1016/j.freeradbiomed.2008.08.026⟩

International audience; Reactive carbonyl compounds (RCC) generated by polyunsaturated fatty acid oxidation alter progressively cellular and tissular proteins by forming adducts on free amino groups and thiol residues (carbonyl stress). Carbonyl scav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f314efeb36e044777ed2a9702b6488d
https://pubmed.ncbi.nlm.nih.gov/18801426

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About the mechanism of interference of silver staining with peptide mass spectrometry

Autor: Alain Van Dorsselaer, Emmanuelle Leize-Wagner, Mireille Chevallet, Thierry Rabilloud, Sylvie Luche, Sophie Richert

Publikováno v: Proteomics
Proteomics, 2004, 4 (4), pp.909-16. ⟨10.1002/pmic.200300642⟩
Proteomics, Wiley-VCH Verlag, 2004, 4 (4), pp.909-16. ⟨10.1002/pmic.200300642⟩

International audience; The mechanism by which silver staining of proteins in polyacrylamide gels interferes with mass spectrometry of peptides produced by proteolysis has been investigated. It was demonstrated that this interference increases with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157161316b30c7aab56e8a3d6ce147dc
https://hal.science/hal-00715512

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Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors

Autor: Jean-Philippe Pin, Francine Acher, Jiang-Feng Liu, Cyril Goudet, Martin Cohen-Gonsaud, Julie Kniazeff, Claire Vol, Laurent Prézeau, Florence Gaven

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2004, 101 (1), pp.378-83. ⟨10.1073/pnas.0304699101⟩
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (1), pp.378-83. ⟨10.1073/pnas.0304699101⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2004, 101 (1), pp.378-83. 〈10.1073/pnas.0304699101〉

Although agonists bind directly in the heptahelical domain (HD) of most class-I rhodopsin-like G protein coupled receptors (GPCRs), class-III agonists bind in the extracellular domain of their receptors. Indeed, the latter possess a large extracellul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8399440e9ad2d2ab33db998840ddcbe4
https://www.hal.inserm.fr/inserm-00319003

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A parallel synthesis scheme for generating libraries of DNA polymerase substrates and inhibitors

Autor: Philippe Marliere, Heike Strobel, Laurence Dugué, Sylvie Pochet

Publikováno v: ChemBioChem
ChemBioChem, 2002, 3 (12), pp.1251-6. ⟨10.1002/1439-7633(20021202)3:123.0.CO;2-1⟩
ChemBioChem, Wiley-VCH Verlag, 2002, 3 (12), pp.1251-6. ⟨10.1002/1439-7633(20021202)3:123.0.CO;2-1⟩

International audience; We report a combinatorial approach aimed at producing in a single step a large family of nucleoside triphosphate derivatives that could be tested for their ability to be substrates for DNA polymerases. We propose as a unique t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e875323639cfcfd688378cb77ab92b1
https://hal-pasteur.archives-ouvertes.fr/pasteur-00166199

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Rhythmic activity from transverse brainstem slice of neonatal rat is modulated by nitric oxide

Autor: F. Maniak, N. Larnicol, O. Pierrefiche

Publikováno v: Neuropharmacology
Neuropharmacology, 2002, 43 (1), pp.85-94
Neuropharmacology, Elsevier, 2002, 43 (1), pp.85-94

We investigated the role of nitric oxide (NO) in the modulation of respiratory-like activity recorded from hypoglossal rootlets in brainstem slices of neonatal rats (P0-P8). Sodium nitroprusside (SNP), S-Nitroso-N-acetyl-D,L-penicillamine (SNAP) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd7c25b573417c656b3b6654dc75375
https://pubmed.ncbi.nlm.nih.gov/12213262

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Synthesis and recognition by DNA polymerases of a reactive nucleoside, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-imidazole-4-hydrazide

Autor: Heike Strobel, Philippe Marlière, Laurence Dugué, Sylvie Pochet

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2002, 30 (9), pp.1869-78. ⟨10.1093/nar/30.9.1869⟩
Nucleic Acids Research, 2002, 30 (9), pp.1869-78. ⟨10.1093/nar/30.9.1869⟩

International audience; We report the synthesis of a new nucleoside, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-imidazole-4-hydrazide (dY(NH2)) as a reactive monomer for DNA diversification. The 5'-triphosphate derivative (dY(NH2)TP, 1) was evaluated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436baca837908776874bf6f41277875f
https://pubmed.ncbi.nlm.nih.gov/11972322

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Differences between cytokine effects in the microcirculation of the rat

Autor: N. Baudry, C. Rasetti, E. Vicaut

Publikováno v: AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 1996, 271 (3), pp.H1186-H1192. ⟨10.1152/ajpheart.1996.271.3.H1186⟩

International audience; We studied by in vivo microscopy in rat cremaster muscle the acute and delayed effects of short exposure to tumor necrosis factor (TNF), interleukin (IL)-1 beta, and IL-6 on basal tone and vascular reactivity of second- to fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005fdeefb6dc67bb64c360dee3ace07a
https://hal-pasteur.archives-ouvertes.fr/pasteur-02865133

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