Zobrazeno 1 - 5
of 5
pro vyhledávání: '"MESH: Histone Methyltransferases"'
Autor:
Teatulohi Matainaho, Doralyn S. Dalisay, Eric Julien, Cholpisut Tantapakul, David E. Williams, Stéphanie Arnould, Fanny Izard, Raymond J. Andersen, Wisanu Maneerat
Publikováno v:
Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2016, 81 (4), pp.1324-1332. ⟨10.1021/acs.joc.5b02569⟩
Journal of Organic Chemistry, American Chemical Society, 2016, 81 (4), pp.1324-1332. ⟨10.1021/acs.joc.5b02569⟩
International audience; Nahuoic acids A-E (1-5) have been isolated from laboratory cultures of a Streptomyces sp. obtained from a tropical marine sediment. The structures of the new polyketides 2-5 were elucidated by analysis of spectroscopic data of
Autor:
Sebastian Amigorena, Paola Romagnoli, Agathe Malbec, Véronique Adoue, Joost P.M. van Meerwijk, Olivier Joffre, Joanna Fourquet, Bénédicte Binet
Publikováno v:
Immunity
Immunity, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
Immunity, Elsevier, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
Immunity, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
Immunity, Elsevier, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
International audience; Upon activation, naive CD4+ T cells differentiate into distinct T cell subsets via processes reliant on epigenetically regulated, lineage-specific developmental programs. Here, we examined the function of the histone methyltra
Autor:
Santiago Ferrer, María Santos Martínez, Laura M. Sanz, Sergio Wittlin, Michael J. Delves, Joachim Caron, Nicholas A. Malmquist, Didier Menard, Matthew J. Fuchter, François Nosten, Robert E. Sinden, Artur Scherf, Patty Chen, Francisco-Javier Gamo, María Belén Jiménez-Díaz, Sandeep Sundriyal, Rossarin Suwanarusk, Laurent Rénia, Sandra Duffy, Iñigo Angulo-Barturen, Andrea Ruecker, Benoit Witkowski, Vicky M. Avery
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Antimicrobial Agents and Chemotherapy, 2015, 59 (2), pp.950-959. ⟨10.1128/AAC.04419-14⟩
Current antimalarials are under continuous threat due to the relentless development of drug resistance by malaria parasites. We previously reported promising in vitro parasite-killing activity with the histone methyltransferase inhibitor BIX-01294 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5216b59f09af9beee15c77b3eee14aea
https://hal.archives-ouvertes.fr/hal-02560661
https://hal.archives-ouvertes.fr/hal-02560661
Publikováno v:
Biomolecules
Biomolecules, MDPI, 2017, 7 (1), pp.3. ⟨10.3390/biom7010003⟩
Biomolecules, 2017, 7 (1), pp.3. ⟨10.3390/biom7010003⟩
Biomolecules, Vol 7, Iss 1, p 3 (2017)
Biomolecules, MDPI, 2017, 7 (1), pp.3. ⟨10.3390/biom7010003⟩
Biomolecules, 2017, 7 (1), pp.3. ⟨10.3390/biom7010003⟩
Biomolecules, Vol 7, Iss 1, p 3 (2017)
International audience; Chromatin can adopt a decondensed state linked to gene transcription (euchromatin) and a condensed state linked to transcriptional repression (heterochromatin). These states are controlled by epigenetic modulators that are act
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2014, 426 (20), pp.3363-3375. ⟨10.1016/j.jmb.2014.05.010⟩
Journal of Molecular Biology, Elsevier, 2014, 426 (20), pp.3363-3375. ⟨10.1016/j.jmb.2014.05.010⟩
International audience; Histone methyltransferases (HKMTs) residing in multi-subunit protein complexes frequently require the presence of β-propeller proteins to achieve their biological functions. Recent biochemical studies have highlighted the fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0610b92d01147bc468f36386a8e6e2
https://hal.archives-ouvertes.fr/hal-03103174
https://hal.archives-ouvertes.fr/hal-03103174