Cynomolgus macaque IL37 polymorphism and control of SIV infection

Autor: Henri-Jean Garchon, Nicolas Tchitchek, Delphine Desjardins, Roger Le Grand, Bruno Vaslin, Takashi Shiina, Nicolas Congy-Jolivet, Nathalie Dereuddre-Bosquet, Brigitte Autran, Ioannis Theodorou, Olivier Lambotte, Antoine Blancher, Alice Aarnink, Shingo Suzuki

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-44235-x⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.7981. ⟨10.1038/s41598-019-44235-x⟩
Scientific Reports, 2019, 9 (1), pp.7981. ⟨10.1038/s41598-019-44235-x⟩

The association between gene polymorphisms and plasma virus load at the set point (SP-PVL) was investigated in Mauritian macaques inoculated with SIV. Among 44 macaques inoculated with 50 AID50, six individuals were selected: three with SP-PVL among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10cd764ad05ff00d00a2e63ad53fe4
http://link.springer.com/article/10.1038/s41598-019-44235-x

Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry

Autor: Amélie Rousselière, Laurence Delbos, Céline Bressollette, Maïlys Berthaume, Béatrice Charreau

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 263, p 263 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 263
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 23 (1), pp.263. ⟨10.3390/ijms23010263⟩

HCMV drives complex and multiple cellular immune responses, which causes a persistent immune imprint in hosts. This study aimed to achieve both a quantitative determination of the frequency for various anti-HCMV immune cell subsets, including CD8 T,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c251519185848aca94e1699be5c0f0b
https://doi.org/10.3390/ijms23010263

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

Autor: Claude Roth, Tineke Cantaert, Chloé Colas, Matthieu Prot, Isabelle Casadémont, Laurine Levillayer, Jessie Thalmensi, Pierre Langlade-Demoyen, Christiane Gerke, Kapil Bahl, Giuseppe Ciaramella, Etienne Simon-Loriere, Anavaj Sakuntabhai

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2019, 10, pp.1424. ⟨10.3389/fimmu.2019.01424⟩
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 2019, 10, pp.1424. ⟨10.3389/fimmu.2019.01424⟩

International audience; Dengue virus (DENV) induces strong T and B cell responses upon infection. Hence, it is difficult to determine the contribution of cell-mediated immunity alone in the long lasting protection against DENV infection and disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748ef15fb2320633791e0ba584774370
https://hal-pasteur.archives-ouvertes.fr/pasteur-03245739/file/fimmu-10-01424.pdf

Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Lung Infections

Autor: Trottein, François, Paget, Christophe

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2018, 9, ⟨10.3389/fimmu.2018.01750⟩
Frontiers in Immunology, Frontiers, 2018, 9, pp.1750. ⟨10.3389/fimmu.2018.01750⟩
Frontiers in Immunology, 2018, 9, pp.1750. ⟨10.3389/fimmu.2018.01750⟩

International audience; The immune system has been traditionally divided into two arms called innate and adaptive immunity. Typically, innate immunity refers to rapid defense mechanisms that set in motion within minutes to hours following an insult.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::22dce94e29209241a8a43a5206dc942b
http://hdl.handle.net/20.500.12210/55830

Increment in Drug Loading on an Antibody-Drug Conjugate Increases Its Binding to the Human Neonatal Fc Receptor in Vitro

Autor: Marie-Claude Viaud-Massuard, Guillaume Brachet, Christophe Arnoult, Nathalie Heuzé-Vourc'h, Nicolas Joubert, Corinne Henriquet, Martine Pugnière, Christine Dhommée, Valérie Gouilleux-Gruart, Renaud Respaud

Publikováno v: Molecular Pharmaceutics
Molecular Pharmaceutics, American Chemical Society, 2016, 13 (4), pp.1405-1412. ⟨10.1021/acs.molpharmaceut.6b00082⟩

International audience; Antibody-drug conjugates, such as brentuximab vedotin (BTXv), are an innovative category of monoclonal antibodies. BTXv is bioconjugated via the chemical reduction of cysteine residues involved in disulfide bonds. Species of B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ad03caf667d8cac03ae684a3fe8ce2
https://pubmed.ncbi.nlm.nih.gov/26900766