Výsledky vyhledávání - "MESH: Histidine"

Histamine in murine narcolepsy: What do genetic and immune models tell us?

Autor: Anne-Laure Morel, Silvia Melzi, Roland S. Liblau, Céline Scoté-Blachon, Yves Dauvilliers, Christelle Peyron

Publikováno v: Brain Pathology
Brain Pathology, Wiley, 2021, ⟨10.1111/bpa.13027⟩
Brain Pathology, 2022, 32 (2), pp.e13027. ⟨10.1111/bpa.13027⟩

International audience; An increased number of histaminergic neurons, identified by labeling histidine-decarboxylase (HDC) its synthesis enzyme, was unexpectedly found in patients with narcolepsy type 1 (NT1). In quest for enlightenment, we evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4490e3482708d0b4df213bb72bef01fa
https://doi.org/10.1111/bpa.13027

Zobrazit plný text záznamu

Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases

Autor: Thomas C. Evans, Andrew F. Gardner, Ece Alpaslan, Kelly M Zatopek, Ludovic Sauguet

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2020, 48 (21), pp.12204-12218. ⟨10.1093/nar/gkaa986⟩
Nucleic Acids Research, 2020, 48 (21), pp.12204-12218. ⟨10.1093/nar/gkaa986⟩

Family D DNA polymerase (PolD) is the essential replicative DNA polymerase for duplication of most archaeal genomes. PolD contains a unique two-barrel catalytic core absent from all other DNA polymerase families but found in RNA polymerases (RNAPs).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fbf1b87ad50a09fe8aa5c33da49784
https://hal-pasteur.archives-ouvertes.fr/pasteur-03086156/document

Zobrazit plný text záznamu

Novel Mutant Phospholipase D from Hemiscorpius lepturus Acts as A Highly Immunogen in BALB/c Mice Against the Lethality of Scorpion Venom

Autor: Delavar Shahbazzadeh, Reza H. Sajedi, Jean-Marc Sabatier, Kamran Pooshang Bagheri, Abouzar Soleimani Moez

Publikováno v: Molecules
Molecules, MDPI, 2020, 25 (7), pp.1673. ⟨10.3390/molecules25071673⟩
Volume 25
Issue 7
Molecules, 2020, 25 (7), pp.1673. ⟨10.3390/molecules25071673⟩
Molecules, Vol 25, Iss 1673, p 1673 (2020)

Hemiscorpius lepturus (H. lepturus) which belongs to the Scorpionidae family, is the deadliest scorpion in Iran. It causes pathological manifestations like dermonecrosis, hemolysis, renal failure, necrotic ulcers, and in some cases, even death. The v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68377b836fdc71f59074a2cded37e91
https://hal-amu.archives-ouvertes.fr/hal-03357863

Zobrazit plný text záznamu

Structural insights into the signalling mechanisms of two-component systems

Autor: Françoise Jacob-Dubuisson, Ariel E. Mechaly, Jean-Michel Betton, Rudy Antoine

Publikováno v: Nature Reviews Microbiology
Nature Reviews Microbiology, Nature Publishing Group, 2018, 16 (10), pp.585-593. ⟨10.1038/s41579-018-0055-7⟩
Nature Reviews Microbiology, 2018, 16 (10), pp.585-593. ⟨10.1038/s41579-018-0055-7⟩

International audience; Two-component systems reprogramme diverse aspects of microbial physiology in response to environmental cues. Canonical systems are composed of a transmembrane sensor histidine kinase and its cognate response regulator. They ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d20865488b33e00d14b96704a8cff2
https://hal.archives-ouvertes.fr/hal-02322157

Zobrazit plný text záznamu

BEST and SOFAST experiments for resonance assignment of histidine and tyrosine side chains in 13C/15N labeled proteins

Autor: Nina Eleni Christou, Bernhard Brutscher

Publikováno v: Journal of Biomolecular NMR
Journal of Biomolecular NMR, 2018, 72 (3-4), pp.115-124. ⟨10.1007/s10858-018-0216-z⟩
Journal of Biomolecular NMR, Springer Verlag, 2018, 72 (3-4), pp.115-124. ⟨10.1007/s10858-018-0216-z⟩

International audience; Aromatic amino-acid side chains are essential components for the structure and function of proteins. We present herein a set of NMR experiments for time-efficient resonance assignment of histidine and tyrosine side chains in u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b7c57f709ae90d2d777a21bd05b950
https://hal.science/hal-02085961

Zobrazit plný text záznamu

The Identification of Phytohormone Receptor Homologs in Early Diverging Fungi Suggests a Role for Plant Sensing in Land Colonization by Fungi

Autor: Herivaux, Anais, de Bernonville, Thomas Duge, Roux, Christophe, Clastre, Marc, Courdavault, Vincent, Gastebois, Amandine, Bouchara, Jean-Philippe, James, Timothy Y., Latge, Jean-Paul, Martin, Francis, Papon, Nicolas

Publikováno v: mBio
mBio, 2017, 8 (1), pp.e01739-16. ⟨10.1128/mBio.01739-16⟩
mBio, American Society for Microbiology, 2017, 8 (1), pp.e01739-16. ⟨10.1128/mBio.01739-16⟩
mBio, Vol 8, Iss 1 (2017)

International audience; Histidine kinases (HKs) are among the most prominent sensing proteins studied in the kingdom Fungi. Their distribution and biological functions in early diverging fungi (EDF), however, remain elusive. We have taken advantage o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cd35ed92bf54e672241e9ffe1075a798
http://europepmc.org/articles/PMC5285503

Zobrazit plný text záznamu

Structural and Biochemical Characterization of an Active Arylamine N-Acetyltransferase Possessing a Non-canonical Cys-His-Glu Catalytic Triad

Autor: Benjamin Pluvinage, Patrick Weber, Inès Li de la Sierra-Gallay, Jean-Marie Dupret, Fernando Rodrigues-Lima, Ahmed Haouz, Xavier Kubiak, Alain Chaffotte

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2013, 288 (31), pp.22493-22505. ⟨10.1074/jbc.m113.468595⟩

International audience; Arylamine N-acetyltransferases (NATs), a class of xenobiotic-metabolizing enzymes, catalyze the acetylation of aromatic amine compounds through a strictly conserved Cys-His-Asp catalytic triad. Each residue is essential for ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdc9c7bb734bd252ed17d80aac629ae
https://doi.org/10.1074/jbc.m113.468595

Zobrazit plný text záznamu

Co-localization of histamine with GABA but not with galanin in the human tuberomamillary nucleus

Autor: B. Fisser, C. Chotard, Suzanne Trottier, Dick F. Swaab, J.-C. Schwartz, Unga A. Unmehopa, Elisabeth Traiffort

Publikováno v: Brain Research, 939, 52-64. Elsevier B.V.
Brain Research
Brain Research, Elsevier, 2002, 939 (1-2), pp.52-64
Brain research, 939(1-2), 52-64. Elsevier

International audience; The presence of GABA and galanin in histaminergic neurons was previously reported in the rodent brain but whether such co-localizations also occur in the human brain was not known. We used in situ hybridization histochemistry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efb8ebc6d0ff4fbbffcdc7bf6616e3a
https://doi.org/10.1016/s0006-8993(02)02546-5

Zobrazit plný text záznamu

Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase

Autor: Silvia Soto Diaz, Ariel E. Mechaly, Alejandro Buschiazzo, Nathalie Sassoon, Pedro M. Alzari, Jean-Michel Betton

Publikováno v: Structure
Structure, Elsevier (Cell Press), 2017, 25 (6), pp.939-944.e3. ⟨10.1016/j.str.2017.04.011⟩
Structure, 2017, 25 (6), pp.939-944.e3. ⟨10.1016/j.str.2017.04.011⟩

International audience; Bacterial two-component systems consist of a sensor histidine kinase (HK) and a response regulator (RR). HKs are homodimers that catalyze the autophosphorylation of a histidine residue and the subsequent phosphoryl transfer to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f635c795abe5f9dd79f5eb9836fdf329
https://pubmed.ncbi.nlm.nih.gov/28552574

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání