Zobrazeno 1 - 10
of 29
pro vyhledávání: '"MESH: High-Throughput Screening Assays"'
Autor:
Felix J. H. Hol, Shailabh Kumar, Manu Prakash, Hongquan Li, Jason L. Rasgon, Sujit Pujhari, Clayton Ellington, Haripriya Vaidehi Narayanan
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.6018. ⟨10.1038/s41467-021-26300-0⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.6018. ⟨10.1038/s41467-021-26300-0⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, 2021, 12 (1), pp.6018. ⟨10.1038/s41467-021-26300-0⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.6018. ⟨10.1038/s41467-021-26300-0⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Mosquito bites transmit a number of pathogens via salivary droplets deposited during blood-feeding, resulting in potentially fatal diseases. Little is known about the genomic content of these nanodroplets, including the transmission dynamics of live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bf15c5a4d9419d9d02fd498e55fa92
Autor:
Florence Larrous, Tae-Hee Kim, Yoonae Ko, Hervé Bourhy, Regis Grailhe, Benoit Besson, Jihwan Song, Sang Chul Lee, Seonhee Kim, David Shum
Publikováno v:
MSphere
MSphere, American Society for Microbiology., 2019, 4 (3), ⟨10.1128/mSphere.00047-19⟩
mSphere, Vol 4, Iss 3, p e00047-19 (2019)
MSphere, 2019, 4 (3), ⟨10.1128/mSphere.00047-19⟩
mSphere, Vol 4, Iss 3 (2019)
mSphere
MSphere, American Society for Microbiology., 2019, 4 (3), ⟨10.1128/mSphere.00047-19⟩
mSphere, Vol 4, Iss 3, p e00047-19 (2019)
MSphere, 2019, 4 (3), ⟨10.1128/mSphere.00047-19⟩
mSphere, Vol 4, Iss 3 (2019)
mSphere
Rabies virus relies on cellular machinery for its replication while simultaneously evading the host immune response. Despite their importance, little is known about the key host factors required for rabies virus infection. Here, we focused on the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0496606160f2b802207359d16a63fe6
https://doi.org/10.1128/msphere.00047-19
https://doi.org/10.1128/msphere.00047-19
Autor:
Cedric Couturier, Sylvie Goussard, Guillaume Duménil, Dorian Obino, Youxin Kong, Ximing Xu, Flore Aubey, Stéphane Renard, Catherine Lapeyrere, Judith Souphron, Jean-Philippe Corre
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (17), pp.8481-8486. ⟨10.1073/pnas.1817757116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (17), pp.8481-8486. ⟨10.1073/pnas.1817757116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (17), pp.8481-8486. ⟨10.1073/pnas.1817757116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (17), pp.8481-8486. ⟨10.1073/pnas.1817757116⟩
International audience; Despite the availability of antibiotics and vaccines, Neisseria meningitidis remains a major cause of meningitis and sepsis in humans. Due to its extracellular lifestyle, bacterial adhesion to host cells constitutes an attract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cd36dd5177d67e6129ff39dca8b82b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03100484/file/Aubey_et_al-Author_manuscript-HAL_Pasteur.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03100484/file/Aubey_et_al-Author_manuscript-HAL_Pasteur.pdf
Autor:
Romain Koszul, Martial Marbouty
Publikováno v:
Trends in Genetics
Trends in Genetics, 2015, 31 (12), pp.673-82. ⟨10.1016/j.tig.2015.10.003⟩
Trends in Genetics, Elsevier, 2015, 31 (12), pp.673-82. ⟨10.1016/j.tig.2015.10.003⟩
Trends in Genetics, 2015, 31 (12), pp.673-82. ⟨10.1016/j.tig.2015.10.003⟩
Trends in Genetics, Elsevier, 2015, 31 (12), pp.673-82. ⟨10.1016/j.tig.2015.10.003⟩
Microbial communities are extremely complex and constitute critical actors of our environment. Genomic analyses of these populations are a dynamic research area but remain limited by the difficulty to assemble full genomes of individual species. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46bccca5fec05ef65f188f92d476238
https://doi.org/10.1016/j.tig.2015.10.003
https://doi.org/10.1016/j.tig.2015.10.003
Autor:
Jaeki Min, Haian Fu, Dima Kozakov, Yuhong Du, David R. Hall, Pierre J. Talbot, Regina Cencic, Raymond Dingledine, Sandor Vajda, Marc Desforges, Jerry Pelletier
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2011, 85 (13), pp.6381-9. ⟨10.1128/JVI.00078-11⟩
Journal of Virology, American Society for Microbiology, 2011, 85 (13), pp.6381-9. ⟨10.1128/JVI.00078-11⟩
Coronaviruses are a family of enveloped single-stranded positive-sense RNA viruses causing respiratory, enteric, and neurologic diseases in mammals and fowl. Human coronaviruses are recognized to cause up to a third of common colds and are suspected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdde7ea09b8398c6a9b548e9afe6cb0
https://doi.org/10.1128/jvi.00078-11
https://doi.org/10.1128/jvi.00078-11
Publikováno v:
Developmental Biology
Developmental Biology, Elsevier, 2011, 350 (2), pp.239-54. ⟨10.1016/j.ydbio.2010.11.026⟩
Developmental Biology; Vol 350
Developmental Biology, Elsevier, 2011, 350 (2), pp.239-54. ⟨10.1016/j.ydbio.2010.11.026⟩
Developmental Biology; Vol 350
International audience; A major prerequisite for the investigation of tissue-specific processes is the identification of cis-regulatory elements. No generally applicable technique is available to distinguish them from any other type of genomic non-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642aa435d8f9688d3601eec8ed56b373
Autor:
Eduati, F, Mangravite, L, Wang, T, Tang, Hongxiang, Bare, J, Huang, R, Norman, T, Kellen, M, Menden, M, Yang, J, Zhan, X, Zhong, R, Xiao, G, Xia, M, Abdo, N, Kosyk, O, Friend, S, Stolovitzky, G, Dearry, A, Tice, R, Simeonov, S, Rusyn, I, Wright, F, Xie, Y, Alaimo, S, Amadoz, A, Ammad-ud-din, M, Chloé-Azencott, A, Bacardit, J, Barron, P, Bernard, E, Beyer, A, Bin, S, van Bömmel, A, Borgwardt, K, Brys, A, Caffrey, B, Chang, J, Christodoulou, E, Clément-Ziza, M, Cohen, T, Cowherd, M, Demeyer, S, Dopazo, J, Elhard, J, Falcao, A, Ferro, A, Friedenberg, D, Giugno, R, Gong, Y, Gorospe, J, Granville, C, Grimm, D, Heinig, M, Hernansaiz, R, Hochreiter, S, Liang-Huang, C, Huska, M, Jiao, Y, Klambauer, G, Kuhn, M, Kursa, M, Kutum, R, Lazzarini, N, Lee, I, Leung, M, K W, Lim, Liu, C, F L, López, Mammana, A, Mayr, A, Michoel, T, Mongiovì, M, Moore, J, Narasimhan, R, Opiyo, S, Pandey, G, Peabody, A, Perner, J, Pulvirenti, A, Rawlik, K, Reinhardt, S, Riffle, C, Ruderfer, D, Sander, A, Savage, R, Scornet, E, Sebastian-Leon, P, Sharan, R, Simon-Gabriel, C, Stoven, V, Sun, J, Tang, H, Teixeira, A, Tenesa, A, Jean-Vert, P, Vingron, M, Walter, T, Whalen, S, Wiśniewska, Z, Wu, Y, Xu, H, Zhang, S, Zhao, J, W Zheng J, Ziwei, D, Simeonov, A, Raymond, R Tice, Saez-Rodriguez, J., NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration
Publikováno v:
Nat Biotechnol
Nature Biotechnology
Nature Biotechnology, Nature Publishing Group, 2015, 33 (9), pp.933-40. ⟨10.1038/nbt.3299⟩
Nature biotechnology
Nature Biotechnology, 2015, 33 (9), pp.933-40. ⟨10.1038/nbt.3299⟩
Nature biotechnology 33(9), 933-940 (2015). doi:10.1038/nbt.3299
Nature Biotechnology, 33 (9)
Nature Biotechnology, Nature Publishing Group, 2015, 33, pp.933-940. ⟨10.1038/nbt.3299⟩
Nature Biotechnology
Nature Biotechnology, Nature Publishing Group, 2015, 33 (9), pp.933-40. ⟨10.1038/nbt.3299⟩
Nature biotechnology
Nature Biotechnology, 2015, 33 (9), pp.933-40. ⟨10.1038/nbt.3299⟩
Nature biotechnology 33(9), 933-940 (2015). doi:10.1038/nbt.3299
Nature Biotechnology, 33 (9)
Nature Biotechnology, Nature Publishing Group, 2015, 33, pp.933-940. ⟨10.1038/nbt.3299⟩
The ability to computationally predict the effects of toxic compounds on humans could help address the deficiencies of current chemical safety testing. Here, we report the results from a community-based DREAM challenge to predict toxicities of enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c668e7b8d997b01bbfeff8dc60d40e
https://hdl.handle.net/11858/00-001M-0000-002A-38D6-911858/00-001M-0000-002A-38D4-D
https://hdl.handle.net/11858/00-001M-0000-002A-38D6-911858/00-001M-0000-002A-38D4-D
Autor:
Yves Nominé, Sebastian Charbonnier, Patricia Cassonnet, Anne Forster, Julie Abdat, Marilyne Blémont, Nicolas Wolff, Kevin Ricquier, Renaud Vincentelli, Katja Luck, Juline Poirson, Marie-Laure Straub, Jérôme Reboul, Jolanta Polanowska, Jeremy Turchetto, Gilles Travé, Francois, Jean-Paul Borg, Yves Jacob, Murielle Masson
Publikováno v:
Nature Methods
Nature Methods, Nature Publishing Group, 2015, 12 (8), pp.787-793. ⟨10.1038/nmeth.3438⟩
Nature Methods, Nature Publishing Group, 2015, 12 (8), pp.787-U154. ⟨10.1038/NMETH.3438⟩
Nature Methods, 2015, 12 (8), pp.787-793. ⟨10.1038/nmeth.3438⟩
Nature methods
Nature Methods, Nature Publishing Group, 2015, 12 (8), pp.787-793. ⟨10.1038/nmeth.3438⟩
Nature Methods, Nature Publishing Group, 2015, 12 (8), pp.787-U154. ⟨10.1038/NMETH.3438⟩
Nature Methods, 2015, 12 (8), pp.787-793. ⟨10.1038/nmeth.3438⟩
Nature methods
Many protein interactions are mediated by small linear motifs interacting specifically with defined families of globular domains. Quantifying the specificity of a motif requires measuring and comparing its binding affinities to all its putative targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d23a387bd6b6333f1fd2c0becc6ef51
https://hal-pasteur.archives-ouvertes.fr/pasteur-02883959
https://hal-pasteur.archives-ouvertes.fr/pasteur-02883959
Autor:
Ana Luisa de Jesus Lopes Ribeiro, Maria Rosalia Pasca, Laurent R. Chiarelli, Giulia Degiacomi, Nathalie Barilone, Marco Fondi, Vadim Makarov, Leonardo B. Marino, Riccardo Manganelli, Marco Bellinzoni, Giuseppe Zanoni, Stewart T. Cole, Francesca Boldrin, Renato Fani, Alessio Porta, Giorgia Mori, Alain R. Baulard, Ruben C. Hartkoorn, Giovanna Riccardi, Jaroslav Blaško, Luiz Pedro S. de Carvalho, Pedro M. Alzari, Zuzana Svetlíková, Ivana Centárová, Elena Kazakova, Sean Ekins, Alexander Lepioshkin, Katarína Mikušová, Marta Esposito
Publikováno v:
Chemistry and Biology
Chemistry and Biology, Elsevier, 2015, 22 (7), pp.917-927. ⟨10.1016/j.chembiol.2015.05.016⟩
Chemistry and Biology, 2015, 22 (7), pp.917-927. ⟨10.1016/j.chembiol.2015.05.016⟩
Chemistry & Biology
Chemistry and Biology, Elsevier, 2015, 22 (7), pp.917-927. ⟨10.1016/j.chembiol.2015.05.016⟩
Chemistry and Biology, 2015, 22 (7), pp.917-927. ⟨10.1016/j.chembiol.2015.05.016⟩
Chemistry & Biology
Summary To combat the emergence of drug-resistant strains of Mycobacterium tuberculosis, new antitubercular agents and novel drug targets are needed. Phenotypic screening of a library of 594 hit compounds uncovered two leads that were active against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97d006b60e385eaf169f479baa402d1
https://hal-pasteur.archives-ouvertes.fr/pasteur-03096090
https://hal-pasteur.archives-ouvertes.fr/pasteur-03096090
Autor:
Pierre Marquet
Publikováno v:
Methods in Molecular Biology (Clifton then Totova)
Methods in Molecular Biology (Clifton then Totova), Humana Press (Springer Imprint), 2012, 902, pp.15-27. 〈10.1007/978-1-61779-934-1_2〉
Methods in Molecular Biology
Methods in Molecular Biology, Humana Press/Springer Imprint, 2012, 902, pp.15-27. ⟨10.1007/978-1-61779-934-1_2⟩
Methods in Molecular Biology ISBN: 9781617799334
Methods in Molecular Biology (Clifton then Totova), Humana Press (Springer Imprint), 2012, 902, pp.15-27. 〈10.1007/978-1-61779-934-1_2〉
Methods in Molecular Biology
Methods in Molecular Biology, Humana Press/Springer Imprint, 2012, 902, pp.15-27. ⟨10.1007/978-1-61779-934-1_2⟩
Methods in Molecular Biology ISBN: 9781617799334
International audience; This chapter reviews recent applications of mass spectrometry to systematic toxicological analysis (STA), where extended lists of compounds of toxicological interest are screened, as well as to the general unknown screening (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130bf5441b7d988d0d0bdb6bf8d74e6c
http://www.hal.inserm.fr/inserm-00925553
http://www.hal.inserm.fr/inserm-00925553