High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry

Autor: Jean Dubuisson, Marlène Dreux, Anne Op De Beeck, Pauline Horellou, François-Loïc Cosset, Thierry Gustot, Cécile Voisset, Gilles Duverlie, Ngoc Vu-Dac

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2006, 87 (9), pp.2577-2581. ⟨10.1099/vir.0.81932-0⟩
Journal of General Virology, 2006, 87 (9), pp.2577-2581. ⟨10.1099/vir.0.81932-0⟩

The neutralizing activity of anti-hepatitis C virus (HCV) antibodies is attenuated by a factor present in human sera, which has been proposed to be high-density lipoproteins (HDLs). HDLs have also been shown to facilitate the entry of HCV pseudoparti

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https://hal.archives-ouvertes.fr/hal-00105505