Anti-C5 antibody treatment for delayed hemolytic transfusion reactions in sickle cell disease

Autor: null Aline Floch, null Alexandre Morel, null Fabian Zanchetta-Balint, null Catherine Cordonnier-Jourdin, null Slimane Allali, null Maximilien Grall, null Ghislaine Ithier, null Benjamin Carpentier, null Sadaf Pakdaman, null Jean-Claude Merle, null Radjiv Goulabchand, null Tackwa Khalifeh, null Ana Berceanu, null Cécile Helmer, null Christelle Chantalat-Auger, null Véronique Frémeaux-Bacchi, null Marc Michel, null Mariane de Montalembert, null Armand Mekontso-Dessap, null France Pirenne, null Anoosha Habibi, null Pablo Bartolucci

Publikováno v: Haematologica
Haematologica, Ferrata Storti Foundation, 2020, 105 (11), pp.2694-2697. ⟨10.3324/haematol.2020.253856⟩

International audience; Delayed hemolytic transfusion reaction (DHTR) is an unpredictable severe complication of transfusion in patients with sickle cell disease (SCD). It presents clinically as a vaso-occlusive crisis (VOC), often associated with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5128c1c7696ed75f2a568f41ddfbc273
https://hal.umontpellier.fr/hal-03281666

Discovery of a New Analgesic Peptide, Leptucin, from the Iranian Scorpion, Hemiscorpius lepturus

Autor: Jean-Marc Sabatier, Soroush Sardari, Sedigheh Bagheri-Ziari, Delavar Shahbazzadeh, Kamran Pooshang Bagheri

Publikováno v: Molecules
Molecules, MDPI, 2021, 26 (9), pp.2580. ⟨10.3390/molecules26092580⟩
Volume 26
Issue 9
Molecules, 2021, 26 (9), pp.2580. ⟨10.3390/molecules26092580⟩
Molecules, Vol 26, Iss 2580, p 2580 (2021)

International audience; Hemiscorpius lepturus scorpion stings do not induce considerable pain based on epidemiological surveys conducted in the southwest part of Iran. Accordingly, this study was aimed to identify the analgesic molecule in H. lepturu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670e938b01811fa520ec7c360c07c48d
https://doi.org/10.3390/molecules26092580

Cytotoxic peptides with insulin-releasing activities from skin secretions of the Italian stream frog Rana italica (Ranidae)

Autor: Conlon, J Michael, Musale, Vishal, Attoub, Samir, Mangoni, Maria Luisa, Leprince, Jérôme, Coquet, Laurent, Jouenne, Thierry, Abdel-Wahab, Yasser, Flatt, Peter, Rinaldi, Andrea, Conlon, J. Michael

Publikováno v: Journal of Peptide Science
Journal of Peptide Science, Wiley, 2017, 23 (10), pp.769-776. ⟨10.1002/psc.3025⟩

International audience; Peptidomic analysis of norepinephrine-stimulated skin secretions from Italian stream frog Rana italica led to the purification and characterization of two host-defense peptides differing by a single amino acid residue belongin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a48f61eed7da544e756bfe1038e20941
https://hal-normandie-univ.archives-ouvertes.fr/hal-01960987

The pathological effects of Heminecrolysin, a dermonecrotic toxin from Hemiscorpius lepturus scorpion venom are mediated through its lysophospholipase D activity

Autor: Haifa Ben Gharsa, Lamia Borchani, Ines Safra, A. Sassi, Delavar Shahbazzadeh, Zakaria Ben Lasfar, Mohamed El Ayeb

Publikováno v: Toxicon
Toxicon, Elsevier, 2013, 68, pp.30-9. ⟨10.1016/j.toxicon.2013.03.012⟩

International audience; We have previously identified Heminecrolysin, a sphingomyelinase D (SMaseD), as the major protein responsible for the main pathological effects observed following Hemiscorpius (H.) lepturus scorpion envenomation. We aimed here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ce87c36ee1e26cd65faeac9daa38b9
https://doi.org/10.1016/j.toxicon.2013.03.012

a cis antisense RNA operates in trans in S. aureus

Autor: Ambre Jousselin, Brice Felden, Nour Sayed

Publikováno v: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2012, 19 (1), pp.105-12. ⟨10.1038/nsmb.2193⟩
Nature Structural and Molecular Biology, 2012, 19 (1), pp.105-12. ⟨10.1038/nsmb.2193⟩

International audience; Antisense RNAs (asRNAs) pair to RNAs expressed from the complementary strand, and their functions are thought to depend on nucleotide overlap with genes on the opposite strand. There is little information on the roles and mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20b084cfabcc6b59fc96a3a16dcc72f
https://doi.org/10.1038/nsmb.2193