Reduced-toxicity myeloablative conditioning regimen using fludarabine and full doses of intravenous busulfan in pediatric patients not eligible for standard myeloablative conditioning regimens: Results of a multicenter prospective phase 2 trial

Autor: Fanny Rialland, Audrey Grain, Myriam Labopin, Gerard Michel, Virginie Gandemer, Catherine Paillard, Cécile Pochon, Laurence Clement, Eolia Brissot, Charlotte Jubert, Anne Sirvent, Pierre Simon Rohrlich, Dominique Plantaz, Jean-Hugues Dalle, Mohamad Mohty

Publikováno v: Bone Marrow Transplantation
Bone Marrow Transplantation, 2022, 57 (11), pp.1698-1703. ⟨10.1038/s41409-022-01769-5⟩

International audience; Data regarding the safety and efficacy of reduced-toxicity conditioning regimen (RTC) prior to allogeneic stem cell transplantation (allo-SCT) to treat hematological malignancies in pediatric patients are limited. This prospec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8303f5d4668f5e5b72eb083cf3649c52
https://doi.org/10.1038/s41409-022-01769-5

Total body irradiation + fludarabine compared to busulfan + fludarabine as 'reduced-toxicity conditioning' for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT

Autor: Giebel, Sebastian, Labopin, Myriam, Sobczyk-Kruszelnicka, Malgorzata, Stelljes, Matthias, Byrne, Jenny, Fegueux, Nathalie, Beelen, Dietrich, Rovira, Montserrat, Spyridonidis, Alexandros, Blaise, Didier, Bornhäuser, Martin, Karadogan, Ihsan, Savani, Bipin, Nagler, Arnon, Mohty, Mohamad, Martin, Sonja, Chevallier, Patrice, Neubauer, Andreas, Damaj, Gandhi, Koc, Yener, Ganser, Arnold, Collin, Matthew, Yakoub-Agha, Ibrahim, Ozdogu, Hakan, Araujo, Mercedes Colorado, Itäla-Remes, Maija, Orchard, Kim, Isaksson, Cecilia, Bethge, Wolfgang, Martin, Hans, Aljurf, Mahmoud, Faber, Edgar, Caballero, Dolores, Zák, Pavel, Leleu, Xavier, Bay, Jacques-Olivier, Rohrlich, Pierre-Simon, Kröger, Nicolaus, Huynh, Anne, Schäfer-Eckart, Kerstin, Milpied, Noel, Lenhoff, Stig, Ho, Aloysius, López, Jose Luis Bello, Mordini, Nicola, Lioure, Bruno, Halaburda, Kazimierz, Olivieri, Attilio, Gedde-Dahl, Tobias, Protheroe, Rachel, Tischer, Johanna, Klammer, Matthias, Clausen, Johannes, Potter, Victoria, Ladetto, Marco, Tilly, Herve, Deconinck, Eric, Brecht, Arne, Müller, Lutz Peter, Heinicke, Thomas, Carrete, Juan Pio Torres, Bazarbachi, Ali, Reményi, Péter, Rubio, Marie Thérèse, Fanin, Renato, Pérez-Simón, Jose Antonio, Niels, Murawski, Diez-Martin, J., Arat, Mutlu, Hermine, Olivier, Socié, Gerard, Cornelissen, Jan, Santarone, Stella, Guyotat, Denis, Bulabois, Claude Eric, Bernasconi, Paolo, Johansson, Jan-Erik, Vrhovac, Radovan, Greinix, Hildegard, Lorenzo, José Luis López, Apte, Shashikant, Craddock, Charles, Kobbe, Guido, Zahrani, Mohsen Al, Dreger, Peter, Lange, Andrzej, Tbakhi, Abdelghani, Meijer, Ellen, Llamas, Carlos Vallejo, Santasusana, Josep Maria Ribera, Corradini, Paolo, Benedetti, Fabio, Rambaldi, Alessandro, Gandemer, Virginie, Malfuson, Jean-Valère, Kaare, Ain, Risitano, Antonio, Petrini, Mario, Selleri, Carmine, Wu, Depei

Publikováno v: Bone Marrow Transplantation, 56(2), 481-491. Nature Publishing Group
Giebel, S, Labopin, M, Sobczyk-Kruszelnicka, M, Stelljes, M, Byrne, J L, Fegueux, N, Beelen, D W, Rovira, M, Spyridonidis, A, Blaise, D, Bornhäuser, M, Karadogan, I, Savani, B N, Nagler, A, Mohty, M & Principal investigators of the contributing institutions 2021, ' Total body irradiation + fludarabine compared to busulfan + fludarabine as “reduced-toxicity conditioning” for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT ', Bone Marrow Transplantation, vol. 56, no. 2, pp. 481-491 . https://doi.org/10.1038/s41409-020-01050-7
Bone Marrow Transplantation
Bone Marrow Transplantation, 2021, 56 (2), pp.481-491. ⟨10.1038/s41409-020-01050-7⟩

International audience; The optimal conditioning for patients with acute myeloid leukemia in first complete remission treated with allogeneic hematopoietic cell transplantation (allo-HCT) has not been defined so far. In this retrospective study, we c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a271bda3480115a5c698ba5b59f0ad1
https://doi.org/10.1038/s41409-020-01050-7

Modalités de mobilisation des cellules souches hématopoïétiques autologues et objectifs cellulaires en cellules CD34 + : recommandations de la Société francophone de greffe de mœlle et de thérapie cellulaire (SFGM-TC)

Autor: Fati Hamzy, Laure Vincent, Anne Brignier, Christine Giraud, Thi Ngoc Phuong Huynh, Francisca Nacimento, Aurélie Levavasseur, Virginie Ader, John De Vos, Katia Bellegarde, Marie-Agnès Guerout-Verite, Yves Rousseau, Ibrahim Yakoub-Agha

Publikováno v: Bulletin du Cancer
Bulletin du Cancer, 2020, 107 (1), pp.S44-S51. ⟨10.1016/j.bulcan.2019.08.007⟩

The modalities of mobilization of hematopoietic stem cells in autologous transplantation have evolved in recent years. The Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) organized the 9th hematopoietic stem cell tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049f368d847e70041abcedcb03c92862
https://doi.org/10.1016/j.bulcan.2019.08.007

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome

Autor: Magnani, A., Semeraro, M., Adam, F., Booth, C., Dupré, L., Morris, E. C., Gabrion, A., Roudaut, C., Borgel, D., Toubert, A., Clave, E., Abdo, C., Gorochov, G., Petermann, R., Guiot, M., Miyara, M., Moshous, D., Magrin, E., Denis, A., Suarez, F., Lagresle, C., Roche, A. M., Everett, J., Trinquand, A., Guisset, M., Bayford, J. Xu, Hacein-Bey-Abina, S., Kauskot, A., Elfeky, R., Rivat, C., Abbas, S., Gaspar, H. B., Macintyre, E., Picard, C., Bushman, F. D., Galy, A., Fischer, A., Six, E., Thrasher, A. J., Cavazzana, M.

Publikováno v: NATURE MEDICINE
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Universidad de las Islas Baleares
Nature Medicine
Nature Medicine, 2022, 28 (1), pp.71-80. ⟨10.1038/s41591-021-01641-x⟩

Patients with Wiskott–Aldrich syndrome (WAS) lacking a human leukocyte antigen-matched donor may benefit from gene therapy through the provision of gene-corrected, autologous hematopoietic stem/progenitor cells. Here, we present comprehensive, long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3f98b89d4b68a773ab2a2e9643726a
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=21058

[Autologous hematopoietic cells for severe autoimmune diseases: Guidelines of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) for immune monitoring and biobanking]

Autor: Lansiaux, Pauline, Loisel, Séverine, Castilla-Llorente, Cristina, Fontenille, Claire, Kabdani, Sarah, Marjanovic, Zora, Pugnet, Grégory, Puyade, Mathieu, Robert, Emilie, Terriou, Louis, Ait Abdallah, Nassim, Maria, Alexandre Thibault Jacques, Michel, Laure, Tréton, Xavier, Yakoub-Agha, Ibrahim, Farge, Dominique

Publikováno v: Bulletin du Cancer
Bulletin du Cancer, 2021, 108 (12), pp.S72-S81. ⟨10.1016/j.bulcan.2021.03.020⟩

International audience; Autologous hematopoietic cell transplantation (AHCT) is a new treatment option for patients with severe autoimmune diseases (AD), based on the use of intensive or myeloablative chemotherapy to eradicate the pathogenic autoreac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37b995f5366bdce491f1c0c4bf9463f9
https://pubmed.ncbi.nlm.nih.gov/34272057