Výsledky vyhledávání - "MESH: Haplotypes"

Functional consequences of archaic introgression and their impact on fitness

Autor: Lluis Quintana-Murci, Maxime Rotival

Publikováno v: Genome Biology, Vol 21, Iss 1, Pp 1-4 (2020)
Genome Biology
Genome Biology, BioMed Central, 2020, 21 (1), pp.3. ⟨10.1186/s13059-019-1920-z⟩
Genome Biology, 2020, 21 (1), pp.3. ⟨10.1186/s13059-019-1920-z⟩

International audience; Anatomically modern humans started to exit Africa for the first time at least 60,000 years ago (ya). Along their journey across the globe, they encountered and admixed with other hominins that are now extinct, such as the Nean

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276112397b3f85f78c334064be6d7468
https://doaj.org/article/6f28d8ac8bca49f5be78b13ea5215ea4

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Cynomolgus macaque IL37 polymorphism and control of SIV infection

Autor: Henri-Jean Garchon, Nicolas Tchitchek, Delphine Desjardins, Roger Le Grand, Bruno Vaslin, Takashi Shiina, Nicolas Congy-Jolivet, Nathalie Dereuddre-Bosquet, Brigitte Autran, Ioannis Theodorou, Olivier Lambotte, Antoine Blancher, Alice Aarnink, Shingo Suzuki

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-44235-x⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.7981. ⟨10.1038/s41598-019-44235-x⟩
Scientific Reports, 2019, 9 (1), pp.7981. ⟨10.1038/s41598-019-44235-x⟩

The association between gene polymorphisms and plasma virus load at the set point (SP-PVL) was investigated in Mauritian macaques inoculated with SIV. Among 44 macaques inoculated with 50 AID50, six individuals were selected: three with SP-PVL among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10cd764ad05ff00d00a2e63ad53fe4
http://link.springer.com/article/10.1038/s41598-019-44235-x

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Validation of genotype imputation in Southeast Asian populations and the effect of single nucleotide polymorphism annotation on imputation outcome

Autor: Nattaya Tangthawornchaikul, Worachart Lert-itthiporn, Anavaj Sakuntabhai, Prida Malasit, Harald Grove, Fumihiko Matsuda, Prapat Suriyaphol, Bhoom Suktitipat

Publikováno v: BMC Medical Genetics, Vol 19, Iss 1, Pp 1-10 (2018)
BMC Medical Genetics
BMC Medical Genetics, BioMed Central, 2018, 19 (1), pp.23. ⟨10.1186/s12881-018-0534-8⟩
BMC Medical Genetics, 2018, 19 (1), pp.23. ⟨10.1186/s12881-018-0534-8⟩

Background Imputation involves the inference of untyped single nucleotide polymorphisms (SNPs) in genome-wide association studies. The haplotypic reference of choice for imputation in Southeast Asian populations is unclear. Moreover, the influence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e19d3eb5a195f5d2a144fe5b0f487c
http://link.springer.com/article/10.1186/s12881-018-0534-8

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Population genetics of Aedes albopictus (Diptera: Culicidae) in its native range in Lao People’s Democratic Republic

Autor: Elliott F. Miot, Maysa T Motoki, Phoutmany Thammavong, Bruna Demari-Silva, Paul T. Brey, Pattamaporn Kittayapong, Nothasine Phommavanh, Dina M. Fonseca, Sébastien Marcombe, Somsanith Chonephetsarath, Jeffrey C. Hertz

Publikováno v: Parasites & Vectors
Parasites & Vectors, 2019, 12 (1), pp.477. ⟨10.1186/s13071-019-3740-0⟩
Parasites & Vectors, Vol 12, Iss 1, Pp 1-12 (2019)

BackgroundThe Asian tiger mosquito,Aedes(Stegomyia)albopictus(Skuse) is an important worldwide invasive species and can be a locally important vector of chikungunya, dengue and, potentially, Zika. This species is native to Southeast Asia where popula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c35781ec5d2a4d1b531e52bf5aac82
https://hal-pasteur.archives-ouvertes.fr/pasteur-03240193/file/s13071-019-3740-0.pdf

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Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9873. ⟨10.1038/s41598-019-46398-z⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

The zoonotic Plasmodium knowlesi parasite is the most common cause of human malaria in Malaysia. Genetic analysis has shown that the parasites are divided into three subpopulations according to their geographic origin (Peninsular or Borneo) and, in B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909d17343900dd426036a19e1743adc1
http://europepmc.org/articles/PMC6614422

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A Founder Effect of c.257 + 2T > C Mutation in NCF2 Gene Underlies Severe Chronic Granulomatous Disease in Eleven Patients

Autor: Khaoula Ben-Farhat, Monia Khemiri, Zohra Fitouri, Sihem Barsaoui, Najla Mekki, Meriem Ben-Ali, Selim Abdelmoula, Mohamed-Neji Guediche, M. R. Barbouche, Samir Boukthir, Saber Hamami, Imen Ben-Mustapha, Amel Ben-Chehida, Jalel Chemli, Karen Rouault, Beya Larguèche

Publikováno v: Journal of Clinical Immunology
Journal of Clinical Immunology, Springer Verlag, 2016, 36 (6), pp.547-554. ⟨10.1007/s10875-016-0299-9⟩

International audience; Chronic granulomatous disease (CGD) is the prototypic functional neutrophil disorder caused by genetic defects in one of the five genes encoding the superoxide-generating nicotinamide adenine dinucleotide phosphate (NADPH)-oxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93add6bc9843dc959ccce1265808deb
https://doi.org/10.1007/s10875-016-0299-9

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Association of rs9939609 Polymorphism with Metabolic Parameters and FTO Risk Haplotype Among Tunisian Metabolic Syndrome

Autor: Ines Kamoun, Mariem Chargui, Florin Grigorescu, Abdelmajid Abid, Khaled Lasram, Hanen Belfki-Benali, Claude Ben Slama, Rym Kefi, Lilia Romdhane, Om Kalthoum Sallem, Habiba Ben Romdhane, Majdi Nagara, Sahar Elouej, Henda Jamoussi, Zinet Turki, Sonia Abdelhak, Sonia Bahri, Redha Attaoua

Publikováno v: Metabolic Syndrome and Related Disorders
Metabolic Syndrome and Related Disorders, Mary Ann Liebert, 2016, 14 (2), pp.121-128. ⟨10.1089/met.2015.0090⟩

International audience; Background: Variants in the fat mass and obesity-associated (FTO) gene are associated with obesity and type 2 diabetes mellitus.Aim of the study: This study aims to assess the association of the rs9939609 variant and haplotype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40196e34877323dcdbc9cad9fcb608ea
https://doi.org/10.1089/met.2015.0090

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A genome wide SNP genotyping study in the Tunisian population: specific reporting on a subset of common breast cancer risk loci

Autor: Sonia Abdelhak, Hamouda Boussen, Olfa Messaoud, Mohamed Samir Boubaker, Majdi Nagara, Mariem Ben Rekaya, Amel Benammar Elgaaied, Lotfi Chouchane, Shan Jingxuan, Lilia Romdhane, Yosr Hamdi, Ridha Mrad

Publikováno v: BMC Cancer
BMC Cancer, BioMed Central, 2018, 18 (1), pp.1295. ⟨10.1186/s12885-018-5133-8⟩
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)

Background Breast cancer is the most common cancer in women worldwide. Around 50% of breast cancer familial risk has been so far explained by known susceptibility alleles with variable levels of risk and prevalence. The vast majority of these breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495d666473b7664a26bd052edc038b59
https://doi.org/10.1186/s12885-018-5133-8

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