Zobrazeno 1 - 8 of 8 pro vyhledávání: '"MESH: HIV-1 / drug effects"'
1
Addition of Maraviroc Versus Placebo to Standard Antiretroviral Therapy for Initial Treatment of Advanced HIV Infection
Autor: Lévy, Yves, Lelièvre, Jean-Daniel, Assoumou, Lambert, Aznar, Esther, Pulido, Federico, Tambussi, Giuseppe, Crespo, Manuel, Meybeck, Agnès, Molina, Jean-Michel, Delaugerre, Constance, Izopet, Jacques, Peytavin, Gilles, Cardon, Fanny, Diallo, Alpha, Lancar, Rémi, Béniguel, Lydie, Costagliola, Dominique
Publikováno v: Annals of Internal Medicine
Annals of Internal Medicine, American College of Physicians, 2020, 172 (5), pp.297-305. ⟨10.7326/M19-2133⟩
International audience; Background: Patients diagnosed with advanced HIV infection have a poor prognosis despite initiation of combined antiretroviral therapy (c-ART). Objective : To assess the benefit of adding maraviroc, an antiretroviral drug with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4325::373c10ef5347e3e82082d01fcacfc7e0
https://ut3-toulouseinp.hal.science/hal-03578146
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2
Performance evaluation of the Vela Dx Sentosa next-generation sequencing system for HIV-1 DNA genotypic resistance
Autor: Pierre Delobel, Caroline Lefebvre, Stéphanie Raymond, Jacques Izopet, Florence Nicot, Luce Minier, Guillaume Martin-Blondel, Romain Carcenac, Florence Abravanel, Agnès Harter
Publikováno v: Journal of Clinical Virology
Journal of Clinical Virology, Elsevier, 2020, 122, pp.104229-104233. ⟨10.1016/j.jcv.2019.104229⟩
Journal of Clinical Virology, 2020, 122, pp.104229. ⟨10.1016/j.jcv.2019.104229⟩
International audience; Background: Patients on antiretroviral therapy could benefit from HIV-1 DNA resistance genotyping for exploring virological failure with low viral load or to guide treatment simplification. Few new generation sequencing data a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8d87573370c8f71dd0b86b647b317a
https://pubmed.ncbi.nlm.nih.gov/31809945
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3
Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and -experienced patients
Autor: Constance Delaugerre, Virginie Ferré, Anne Maillard, Vincent Calvez, Audrey Mirand, Anne-Geneviève Marcelin, Corinne Amiel, Julia Dina, Coralie Pallier, Hélène Le Guillou-Guillemette, Stéphanie Raymond, D. B. Fofana, Thomas Mourez, Hélène Jeulin, Samira Fafi-Kremer, Brigitte Montes, Pantxika Bellecave, Sophie Vallet, Thuy Van Nguyen, Diane Descamps, Catherine Roussel, Maxime Grude, Mary-Anne Trabaud, Charlotte Charpentier, Laurence Bocket, Philippe Flandre, Laura Le Guen, Anne Signori-Schmuck
Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1368-1375. ⟨10.1093/jac/dkz021⟩
International audience; Objectives: To describe integrase strand transfer inhibitor (INSTI) resistance profiles and factors associated with resistance in antiretroviral-naive and -experienced patients failing an INSTI-based regimen in clinical practi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b81aa0dcf188502b617cb295d23cbb
https://hal-normandie-univ.archives-ouvertes.fr/hal-02154049
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4
Trimeric heptad repeat synthetic peptides HR1 and HR2 efficiently inhibit HIV-1 entry
Autor: Mzoughi, Olfa, Teixido, Meritxell, Planès, Rémi, Serrero, Manutea, Hamimed, Ibtissem, Zurita, Esther, Moreno, Miguel, Granados, Giovana, Lakhdar-Ghazal, Faouzi, BenMohamed, Lbachir, Giralt, Ernest, Bahraoui, Elmostafa
Publikováno v: Bioscience Reports
Bioscience Reports, 2019, 39 (9), pp.1-15. ⟨10.1042/BSR20192196⟩
Bioscience reports, vol 39, iss 9
International audience; The trimeric heptad repeat domains HR1 and HR2 of the human immunodeficiency virus 1 (HIV-1) gp41 play a key role in HIV-1-entry by membrane fusion. To develop efficient inhibitors against this step, the corresponding trimeric
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d6dfc3e3783a50d8ce5ed458ed29d60e
https://doi.org/10.1042/BSR20192196
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5
Once‐daily darunavir/ritonavir 400/100 mg in triple therapy: efficacy and penetration in seminal compartment in ANRS ‐165 DARULIGHT study
Autor: François Raffi, Jean-Michel Molina, Christine Katlama, Marie-Laure Chaix, Juliette Saillard, Minh Patrick Lê, Gilles Peytavin, Sylvie Chevret, Sebastien Gallien, Yazdan Yazdanpanah, Pierre Delobel
Publikováno v: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 2019, 85 (1), pp.277-280. ⟨10.1111/bcp.13796⟩
International audience; A key concern for reduced-dose antiretroviral regimens in maintenance strategies in HIV-infected patients is virological efficacy, as assessed by the suppression of HIV-RNA in blood and reservoirs, such as the genital tract. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d0799604e0f88f57976c2ef0ea70a0
https://ut3-toulouseinp.hal.science/hal-03639183
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6
Stable prevalence of transmitted drug resistance mutations and increased circulation of non-B subtypes in antiretroviral-naive chronically HIV-infected patients in 2015/2016 in France
Autor: Gilles Peytavin, Mary-Anne Trabaud, Anne Signori-Schmuck, Charlotte Charpentier, Marc Wirden, Cécile Henquell, Laurence Bocket, Catherine Delamare, Samira Fafi-Kremer, Jacques Izopet, Chakib Allaoui, Georges Dos Santos, A. Beby-Defaux, Benoit Visseaux, Virginie Ferré, Coralie Pallier, Diane Descamps, Stéphanie Marque-Juillet, Lambert Assoumou, Magali Bouvier-Alias, Sophie Vallet, Alexis de Rougemont, Hélène Le Guillou-Guillemette, Vincent Calvez, Stéphanie Raymond, Corinne Amiel, Honorine Fenaux, Anne De Monte, Francis Barin, Anne Krivine, Véronique Avettand-Fenoel, Annick Allardet-Servent, Jean-Christophe Plantier, Rachid Ait-Namane, Laurence Morand-Joubert, Marie-Laure Chaix, Camille Tumiotto, Maxime Grude, Anne Maillard, Laurence Courdavault, Brigitte Montes
Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (5), pp.1417-1424. ⟨10.1093/jac/dkz011⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1417-1424. ⟨10.1093/jac/dkz011⟩
International audience; Objectives: We estimated the prevalence of transmitted-drug-resistance-associated mutations (TDRAMs) in antiretroviral-naive chronically HIV-1-infected patients.Patients and methods: TDRAMs were sought in samples from 660 diag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d3c4f5ee0320db9d5644b1b661f53d
https://pubmed.ncbi.nlm.nih.gov/30753724
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7
Impact of the mutational load on the virological response to a first-line rilpivirine-based regimen
Autor: Jacques Izopet, Chloé Dimeglio, Florence Nicot, Caroline Lefebvre, Romain Carcenac, Nicolas Jeanne, Stéphanie Raymond
Publikováno v: Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (3), pp.718-721. ⟨10.1093/jac/dky495⟩
Journal of Antimicrobial Chemotherapy, 2018, 74 (3), pp.718-721. ⟨10.1093/jac/dky495⟩
Author(s): Dimeglio, Chloe; Raymond, Stephanie; Nicot, Florence; Jeanne, Nicolas; Carcenac, Romain; Lefebvre, Caroline; Izopet, Jacques; French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group | Abstract: Ob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803e02fe658eba4c3b08ac8052064348
https://pubmed.ncbi.nlm.nih.gov/30535228
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8
Early Antiretroviral Therapy Preserves Functional Follicular Helper T and HIV-Specific B Cells in the Gut Mucosa of HIV-1-Infected Individuals
Autor: Valérie Lorin, Mathieu Surenaud, Cyril Planchais, Hugo Mouquet, Mathieu Fusaro, Sophie Hue, Marie-Hélène Delfau-Larue, Nabila Seddiki, Clara Ibanez, Laurent Hocqueloux, Michael J. Levy, Thierry Prazuck, S. Gallien, Yves Levy, Ayrin Kök, Christiane Copie, Jean-Daniel Lelièvre, Laurent Lefrou
Publikováno v: Journal of Immunology
Journal of Immunology, 2018, 200 (10), pp.3519-3529. ⟨10.4049/jimmunol.1701615⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2018, 200 (10), pp.3519-3529. ⟨10.4049/jimmunol.1701615⟩
HIV-1 infection is associated with B cell dysregulation and dysfunction. In HIV-1–infected patients, we previously reported preservation of intestinal lymphoid structures and dendritic cell maturation pathways after early combination antiretroviral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2622102e5901a8a1bf6c99603c6ba9c4
https://hal-pasteur.archives-ouvertes.fr/pasteur-02634634/document
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