Výsledky vyhledávání - "MESH: HIV Infections / immunology"

Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals

Autor: Guillaume Martin-Blondel, Jacques Izopet, Mary Requena, Bertrand Suc, Laurent Alric, Manon Nayrac, Nicolas Carrere, Pierre Delobel, Karl Barange, Claire Loiseau, Michelle Cazabat

Publikováno v: Mucosal Immunology
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩

International audience; Gut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7063cc54ac3d26c97d0c23435a80444c
https://ut3-toulouseinp.hal.science/hal-03157449

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Virological and immunological impact of integrase inhibitor-based regimens initiated during primary HIV-1 infection

Autor: Claudine Duvivier, Raphael Veil, Laurent Cotte, Laure Surgers, Antoine Cheret, Rémonie Seng, Caroline Lascoux Combe, Jacques Reynes, Laurence Meyer, Laurent Tran, David Rey, Clotilde Allavena, Isabelle Poizot-Martin, Pierre Delobel, Cécile Goujard

Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2020, 34 (4), pp.493-500. ⟨10.1097/QAD.0000000000002447⟩

International audience; Design: Current international guidelines recommend either boosted protease inhibitor (PI/r)-based or integrase inhibitors (INSTI)-based regimens during primary HIV infection (PHI), even though the latter have only demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4884625e388980901de465e7b1235fbe
https://pubmed.ncbi.nlm.nih.gov/31764069

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A high mucosal blocking score is associated with HIV protection

Autor: Mario Clerici, Bernard Verrier, Norma Rallón, Blandine Chanut, Jorge del Romero, Alexandre Girard, Christian Genin, Stéphane Paul, Mara Biasin, Frédéric Lucht, Fabienne Jospin, José M. Benito, Jean Jacques Pin, Fahd Benjelloun, Carmen Rodríguez

Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2019, 33 (3), pp.411-423. ⟨10.1097/QAD.0000000000002099⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2019, 33 (3), pp.411-423. ⟨10.1097/QAD.0000000000002099⟩

International audience; BACKGROUND:Early steps of HIV infection are mediated by the binding of the envelope to mucosal receptors as α4β7 and the C-type lectins DC-SIGN and langerin. Previously Env-specific B-cell responses have been reported in hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e526359b0fc46cf5230fb418fcd34f
https://hal.archives-ouvertes.fr/hal-02351387

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In Untreated HIV-1–Infected Children, PBMC-Associated HIV DNA Levels and Cell-Free HIV RNA Levels Are Correlated to Distinct T-lymphocyte Populations

Autor: Céline Didier, Christine Rouzioux, Stéphane Blanche, Marianne Burgard, Daniel Scott-Algara, Yves Rivière, Florence Buseyne

Publikováno v: Journal of Acquired Immune Deficiency Syndromes
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩
Journal of Acquired Immune Deficiency Syndromes, 2010, 53 (5), pp.553-63. <10.1097/QAI.0b013e3181cf060f>
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. 〈10.1097/QAI.0b013e3181cf060f〉
Journal of Acquired Immune Deficiency Syndromes-JAIDS
Journal of Acquired Immune Deficiency Syndromes-JAIDS, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩

International audience; Background: Clinical studies support biologically independent roles of cell-free HIV particles and HIV-infected cells in disease progression. The associations between the level of infected cells and immune markers have been po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac44837a51de96786cecad033b47989
https://doi.org/10.1097/qai.0b013e3181cf060f

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High proportion of PD-1-expressing CD4 + T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence

Autor: Guillaume Pourcher, Abderaouf Damouche, Benoit Favier, Jean Jacques Lataillade, Bruno Vaslin, Valérie Pourcher, Christine Bourgeois, Elodie Busson, Olivier Lambotte, Mélanie Le Van, Stéphane Benoist, Thierry Lazure, Julien Adam, Michaela Müller-Trutwin

Publikováno v: European Journal of Immunology
European Journal of Immunology, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩
European Journal of Immunology, Wiley-VCH Verlag, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩

We and others have demonstrated that adipose tissue is a reservoir for HIV. Evaluation of the mechanisms responsible for viral persistence may lead to ways of reducing these reservoirs. Here, we evaluated the immune characteristics of adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca3eda57bdcf8b871126b640f92b28
https://doi.org/10.1002/eji.201747060

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Actin’ on HIV: How Dendritic Cells Spread Infection

Autor: Daniel A. Donahue, Olivier Schwartz

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2016, 19 (3), pp.267-269. ⟨10.1016/j.chom.2016.02.016⟩
Cell Host and Microbe, 2016, 19 (3), pp.267-269. ⟨10.1016/j.chom.2016.02.016⟩

Whereas human dendritic cells (DCs) are largely resistant to productive infection with HIV-1, they have a unique ability to take up the virus and transmit it efficiently to T lymphocytes through a process of trans-infection or trans-enhancement. To e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc223c460f63b9a8d19d4c8e9d0288d
https://hal-pasteur.archives-ouvertes.fr/pasteur-01372388

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Pivotal role of M-DC8+ monocytes from viremic HIV-infected patients in TNFα overproduction in response to microbial products

Autor: Nipa Decroix, Anne Hosmalin, Jean-Pierre Jourdain, Anne-Sophie Liovat, Odile Launay, Christiane Deveau, Michaela Müller-Trutwin, Matthieu Goguet, Charles-Antoine Dutertre, Sonia Amraoui, Pierre Loulergue, Laurence Meyer, Vincent Feuillet, Séverine A. Degrelle, Annalisa DeRosa, Cécile Goujard, Yolande Richard, Lene Vimeux

Publikováno v: Blood
Blood, American Society of Hematology, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩
Blood, 2012, 120 (11), pp.2259-2268. ⟨10.1182/blood-2012-03-418681⟩

HIV infects activated CD4+ T cells and induces their depletion. Progressive HIV infection leading to AIDS is fueled by chronic immune hyperactivation, mediated by inflammatory cytokines like TNFα. This has been related to intestinal epithelial damag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb5a4137f647010c8abf343dbc7b070
https://doi.org/10.1182/blood-2012-03-418681

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TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB

Autor: Viraga Haridas, Yoann Madec, Thim Sok, Anne E. Goldfeld, Didier Laureillard, Laurence Borand, Olivier Marcy, Sun Sath, Jean-François Delfraissy, Polidy Pean, François-Xavier Blanc, Sarin Chan, Erdyni N. Tsitsikov, Luke D. Jasenosky

Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2015, 29 (3), pp.263-273. ⟨10.1097/qad.0000000000000546⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2015, 29 (3), pp.263-273. ⟨10.1097/qad.0000000000000546⟩

The authors are indebted to Wallis Annenberg whose generosity made this study possible, and to John Moores for his generous gift. We are grateful to Francoise Barré-Sinoussi for her help, advice, and support over the years. We thank Eric Nerrienet,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca7dacefbe83a100293b8aeeb08a2dc
https://hal.umontpellier.fr/hal-02137135

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Apolipoprotein H expression is associated with IL28B genotype and viral clearance in hepatitis C virus infection

Publikováno v: Journal of Hepatology
Journal of Hepatology, Elsevier, 2014, 61 (4), pp.770-776. ⟨10.1016/j.jhep.2014.05.040⟩
Journal of Hepatology; Vol 61
Journal of Hepatology, 2014, 61 (4), pp.770-776. ⟨10.1016/j.jhep.2014.05.040⟩

International audience; BACKGROUND & AIMS:HCV requires host lipid metabolism for replication, and apolipoproteins have been implicated in the response to treatment.METHODS:We examined plasma apolipoprotein concentrations in three cohorts of patients:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65e22babc37f616ddcec22f8adee8ac
https://hal-pasteur.archives-ouvertes.fr/pasteur-01384212

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HIV-associated chronic immune activation

Autor: Michaela Müller-Trutwin, Mirko Paiardini

Publikováno v: Immunological Reviews
Immunological Reviews, 2013, 254 (1), pp.78-101. ⟨10.1111/imr.12079⟩
Immunological Reviews, Wiley, 2013, 254 (1), pp.78-101. ⟨10.1111/imr.12079⟩

International audience; Systemic chronic immune activation is considered today as the driving force of CD4(+) T-cell depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune activation persists even in HIV-infected patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b122110966584d985efebb95a3e8aab
https://pubmed.ncbi.nlm.nih.gov/23772616

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