Výsledky vyhledávání - "MESH: Glucosyltransferases"

Mechanistic Insights into the Retaining Glucosyl-3-phosphoglycerate Synthase from Mycobacteria*

Autor: Ha T. Pham, Ana Carreras-González, Devinder Kaur, David Albesa-Jové, Francis Schaeffer, Sonia Lopez-Fernandez, Patrick J. Brennan, Mary Jackson, Saioa Urresti, Petra Gest, Mark J. van der Woerd, Pedro M. Alzari, Marcelo E. Guerin

Publikováno v: Journal of Biological Chemistry; Vol 287
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩
Journal of Biological Chemistry, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩

International audience; Considerable progress has been made in recent years in our understanding of the structural basis of glycosyl transfer. Yet the nature and relevance of the conformational changes associated with substrate recognition and cataly

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CGTase-Catalysed cis -Glucosylation of L -Rhamnosides for the Preparation of Shigella flexneri 2a and 3a Haptens

Autor: Hugues Driguez, Carole Urbach, Catherine Guerreiro, Sami Halila, Laurence A. Mulard, Sylvie Armand

Publikováno v: ChemBioChem
ChemBioChem, 2014, 15 (2), pp.293-300. ⟨10.1002/cbic.201300597⟩
ChemBioChem, Wiley-VCH Verlag, 2014, 15 (2), pp.293-300. ⟨10.1002/cbic.201300597⟩

International audience; We report the enzymatic synthesis of α-D-glucopyranosyl-(1→4)-α-L-rhamnopyranoside and α-D-glucopyranosyl-(1→3)-α-L-rhamnopyranoside by using a wild-type transglucosidase in combination with glucoamylase and glucose ox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba300b821589796081ad79b816c4201
https://hal-pasteur.archives-ouvertes.fr/pasteur-02043361

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Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus

Autor: Anne, Beauvais, Silvia, Bozza, Olaf, Kniemeyer, Cécile, Formosa, Céline, Formosa, Viviane, Balloy, Christine, Henry, Robert W, Roberson, Etienne, Dague, Michel, Chignard, Axel A, Brakhage, Luigina, Romani, Jean-Paul, Latgé

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2013, 9 (11), pp.e1003716. ⟨10.1371/journal.ppat.1003716⟩
PLoS Pathogens, Public Library of Science, 2013, 9 (11), pp.e1003716. ⟨10.1371/journal.ppat.1003716⟩
PLoS Pathogens, Vol 9, Iss 11, p e1003716 (2013)
PLoS Pathogens; Vol 9

α-(1,3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and AGS3) controlling the biosynthesis of α-(1,3)-glucan in this fungal species. Deletion of al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4040f537c008704ca635403939d5912a
https://doi.org/10.1371/journal.ppat.1003716

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Sphingolipids and response to chemotherapy

Autor: Marie-Thérèse Dimanche-Boitrel, Amélie Rébillard

Publikováno v: Handb Exp Pharmacol
Sphingolipids in Disease
Handb Exp Pharmacol, Vsevolod Gurevich, 2013, 216, pp.73-91. ⟨10.1007/978-3-7091-1511-4_4⟩
Handb Exp Pharmacol, 2013, 216, 216, pp.73-91. ⟨10.1007/978-3-7091-1511-4_4⟩
Sphingolipids in Disease ISBN: 9783709115107

International audience; Chemotherapy is frequently used to treat primary or metastatic cancers, but intrinsic or acquired drug resistance limits its efficiency. Sphingolipids are important regulators of various cellular processes including proliferat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab6a130ebcf39822efaf0566ef47c27
https://www.hal.inserm.fr/inserm-00871347

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Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Autor: Vishukumar Aimanianda, Isabelle Mouyna, Yves F. Dufrêne, Laetitia Muszkieta, Anne Beauvais, Sven Krappmann, Jean-Paul Latgé, Rémi Beau, David Alsteens, Cesar Roncero, Cristina Jiménez-Ortigosa, Stéphane Pire

Publikováno v: Antimicrobial Agents and Chemotherapy, Vol. 56, no.12, p. 6121-6131 (2012)
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2012, 56 (12), pp.6121-6131. ⟨10.1128/AAC.00752-12⟩
Antimicrobial Agents and Chemotherapy, 2012, 56 (12), pp.6121-6131. ⟨10.1128/AAC.00752-12⟩

Aspergillus fumigatus has two chitin synthases ( CSMA and CSMB ) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synthases, single and double csm mutant strains were construct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3c7144acc4a4610dd1f3cd32b4c42
https://hdl.handle.net/2078/119971

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α1,3 glucans are dispensable in Aspergillus fumigatus

Autor: Jean-Paul Latgé, Anne Beauvais, Christine Henry

Publikováno v: Eukaryotic Cell
Eukaryotic Cell, American Society for Microbiology, 2012, 11 (1), pp.26-29. ⟨10.1128/EC.05270-11⟩
Eukaryotic Cell, 2012, 11 (1), pp.26-29. ⟨10.1128/EC.05270-11⟩

A triple α1,3 glucan synthase mutant of Aspergillus fumigatus obtained by successive deletions of the three α1,3 glucan synthase genes ( AGS1 , AGS2 , and AGS3 ) has a cell wall devoid of α1,3 glucans. The lack of α1,3 glucans affects neither con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68898a378311d8fce8a33b9b8fec4bc3
https://hal-pasteur.archives-ouvertes.fr/pasteur-01725833/file/26_002.pdf

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Links between lipid homeostasis, organelle morphodynamics and protein trafficking in eukaryotic and plant secretory pathways

Autor: Valérie Wattelet-Boyer, Su Melser, Yannick Bellec, Jean-Denis Faure, Brigitte Batailler, Martine Peypelut, Diana Molino, Patrick Moreau, Maryse Laloi

Publikováno v: Plant Cell Reports
Plant Cell Reports, Springer Verlag, 2011, 30 (2), pp.177-93. ⟨10.1007/s00299-010-0954-1⟩

International audience; The role of lipids as molecular actors of protein transport and organelle morphology in plant cells has progressed over the last years through pharmacological and genetic investigations. The manuscript is reviewing the roles o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cc1d2f6e819f307fd21c9d64145edc
https://hal.archives-ouvertes.fr/hal-00715782

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Plasma membrane microdomains from hybrid aspen cells are involved in cell wall polysaccharide biosynthesis

Autor: Vincent Bulone, Soraya Djerbi, Nicolas Sindt, Michel Guichardant, Laurence Bessueille, Tuula T. Teeri

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2009, 420 (1), pp.93-103. ⟨10.1042/BJ20082117⟩

International audience; Detergent-resistant plasma membrane microdomains [DRMs (detergent-resistant membranes)] were isolated recently from several plant species. As for animal cells, a large range of cellular functions, such as signal transduction,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d627c362281b86d7f1774cce54eb07a
https://hal.archives-ouvertes.fr/hal-00917346

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Cell wall polysaccharide synthases are located in detergent-resistant membrane microdomains in oomycetes

Autor: Laurence Bessueille, Anne Briolay, Michel Guichardant, Nicolas Sindt, Christian Deshayes, Vincent Bulone, Jamel Bouzenzana

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2009, 75 (7), pp.1938-49. ⟨10.1128/AEM.02728-08⟩

The pathways responsible for cell wall polysaccharide biosynthesis are vital in eukaryotic microorganisms. The corresponding synthases are potential targets of inhibitors such as fungicides. Despite their fundamental and economical importance, most p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e997baeed815673693579865fe675b
https://hal.archives-ouvertes.fr/hal-00631309

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Organization of cellulose synthase complexes involved in primary cell wall synthesis in Arabidopsis thaliana

Autor: François Parcy, Samantha Vernhettes, Herman Höfte, Thierry Desprez, Martine Gonneau, Michal Juraniec, Zaneta Pochylova, Elizabeth Faris Crowell, Hélène Jouy

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104 (39), pp.15572-7. ⟨10.1073/pnas.0706569104⟩
Proceedings of the National Academy of Sciences of the United States of America 39 (104), 15572-15577. (2007)
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (39), pp.15572-7. ⟨10.1073/pnas.0706569104⟩
Proceedings of the National Academy of Sciences of the United States of America 39 (104), 15572-7. (2007)

In all land plants, cellulose is synthesized from hexameric plasma membrane complexes. Indirect evidence suggests that in vascular plants the complexes involved in primary wall synthesis contain three distinct cellulose synthase catalytic subunits (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a853968951816da267ff10fe05209d
https://hal.archives-ouvertes.fr/hal-00198484

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