Výsledky vyhledávání - "MESH: Glucose Transporter Type 4"

Interleukin-1β-Induced Insulin Resistance in Adipocytes through Down-Regulation of Insulin Receptor Substrate-1 Expression

Autor: Mireille Cormont, T Grémeaux, Jennifer Jager, Yannick Le Marchand-Brustel, Jean-François Tanti

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2007, 148 (1), pp.241-51. ⟨10.1210/en.2006-0692⟩

Inflammation is associated with obesity and insulin resistance. Proinflammatory cytokines produced by adipose tissue in obesity could alter insulin signaling and action. Recent studies have shown a relationship between IL-1beta level and metabolic sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502a891031b530affe16248045bf5864
https://doi.org/10.1210/en.2006-0692

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Early pre-diabetic state alters adaptation of myocardial glucose metabolism during ischemia in rats

Autor: Stéphane Tanguy, Catherine Ghezzi, Joël de Leiris, Corinne Berthonneche, Sandrine Morel, Marie-Claire Toufektsian, Pascale Perret, François Boucher

Publikováno v: Molecular and Cellular Biochemistry
Molecular and Cellular Biochemistry, Springer Verlag, 2005, 272 (1-2), pp.9-17. ⟨10.1007/s11010-005-4778-1⟩

International audience; Pre-diabetic subjects with high insulin secretory capacity have double risk of cardiovascular disease compared with subjects who do not develop insulin-resistance. It is well established that the ability of the myocardium to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affe6d765b998293a7b3897451e8d85c
https://doi.org/10.1007/s11010-005-4778-1

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Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models

Autor: Roland Govers, Nancy Zaarour, Yannick Le Marchand-Brustel, Marion Berenguer

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2012, 445 (2), pp.265-73
Biochemical Journal, Portland Press, 2012, 445 (2), pp.265-73. ⟨10.1042/BJ20120232⟩
Biochemical Journal, 2012, 445 (2), pp.265-73. ⟨10.1042/BJ20120232⟩

International audience; GLUT4 (glucose transporter 4) is responsible for the insulin-induced uptake of glucose by muscle and fat cells. In non-stimulated (basal) cells, GLUT4 is retained intracellularly, whereas insulin stimulation leads to its trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f424f683b4d9a6d4fd66f88cbd7df428
https://hal.archives-ouvertes.fr/hal-01478346

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Molecular mechanisms of GLUT4 regulation in adipocytes

Autor: Roland Govers

Publikováno v: Diabetes and Metabolism
Diabetes and Metabolism, Elsevier Masson, 2014, 40 (6), pp.400-10
Diabetes & Metabolism
Diabetes & Metabolism, Elsevier Masson, 2014, 40 (6), pp.400-10
Diabetes and Metabolism, Elsevier Masson, 2014, 40 (6), pp.400-410. ⟨10.1016/j.diabet.2014.01.005⟩

Insulin resistance is strongly linked to type 2 diabetes and associated with a reduced uptake of glucose by muscle and adipose tissue. The transporter that is responsible for this uptake and whose function is disturbed in insulin resistance and type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aeb9565cd436bef251f546c798c4f7
https://hal.archives-ouvertes.fr/hal-01478338

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Cellular regulation of glucose uptake by glucose transporter GLUT4

Autor: Roland Govers

Publikováno v: Advances in Clinical Chemistry
Advances in Clinical Chemistry, Elsevier, 2014, pp.173-240
Advances in Clinical Chemistry, 66, Elsevier, 301 p., 2014, Advances in Clinical Chemistry, 978-0-12-801401-1. ⟨10.1016/B978-0-12-801401-1.00006-2⟩

International audience; GLUT4 is regulated by its intracellular localization. In the absence of insulin, GLUT4 is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation (and contraction in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0b1881c32f5f6e1e5e15d226364522
https://hal.archives-ouvertes.fr/hal-01478336

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Dimethyl sulfoxide enhances GLUT4 translocation through a reduction in GLUT4 endocytosis in insulin-stimulated 3T3-L1 adipocytes

Autor: Marion Berenguer, Andrey A. Gurtovenko, Jinzhong Zhang, Yannick Le Marchand-Brustel, Laurène Martinez, Roland Govers, Teresa Gonzalez, Tao Xu, M. Christine Bruce

Publikováno v: Biochimie
Biochimie, Elsevier, 2011, 93 (4), pp.697-709. ⟨10.1016/j.biochi.2010.12.013⟩
Biochimie, Elsevier, 2011, 93 (4), pp.697-709
Biochimie, 2011, 93 (4), pp.697-709. ⟨10.1016/j.biochi.2010.12.013⟩

International audience; Insulin increases muscle and fat cell glucose uptake by inducing the translocation of glucose transporter GLUT4 from intracellular compartments to the plasma membrane. Here, we have demonstrated that in 3T3-L1 adipocytes, DMSO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb64590c601571698cf87e2d6f2dd773
https://hal.archives-ouvertes.fr/hal-01478348

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GLUT4 molecules are recruited at random for insertion within the plasma membrane upon insulin stimulation

Autor: Roland Govers, Yannick Le Marchand-Brustel, Marion Berenguer

Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2010, 584 (3), pp.537-42

International audience; Glucose transporter 4 (GLUT4) is efficiently retained intracellularly. Here, we investigated the insulin-induced reduction of retention. While increasing insulin concentrations led to gradual increases in both the amount of re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9e37d12ea2a49ea25ac7213db9d25b
https://hal.archives-ouvertes.fr/hal-01478369

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A serum factor induces insulin-independent translocation of GLUT4 to the cell surface which is maintained in insulin resistance

Autor: Marion Berenguer, Sophie Giorgetti-Peraldi, Roland Govers, Laurène Martinez, Yannick Le Marchand-Brustel

Publikováno v: PLoS ONE
PLoS ONE, 2010, 5 (12), pp.e15560. ⟨10.1371/journal.pone.0015560⟩
PLoS ONE, Vol 5, Iss 12, p e15560 (2010)
PLoS ONE, Public Library of Science, 2010, 5 (12), pp.e15560. ⟨10.1371/journal.pone.0015560⟩

International audience; In response to insulin, glucose transporter GLUT4 translocates from intracellular compartments towards the plasma membrane where it enhances cellular glucose uptake. Here, we show that sera from various species contain a facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3034e36898b6b6de2f6d1c97127942
https://hal.science/hal-01478354/document

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Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during calorie restriction in obese subjects but are not related to diet-induced changes in insulin sensitivity

Autor: Dominique Langin, Vladimir Stich, Michaela Vitkova, Nathalie Viguerie, Cedric Moro, Jiri Hanacek, Eva Klimcakova, Magda Bajzova, Jan Polak, Carine Valle, Frédéric Capel, Michaela Kovacikova, Blanka Richterova, Jindra Hejnova

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2007, 92 (6), pp.2330-5. ⟨10.1210/jc.2006-2668⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2007, 92 (6), pp.2330-5. ⟨10.1210/jc.2006-2668⟩

0021-972X (Print) 0021-972X (Linking) Journal Article Research Support, Non-U.S. Gov't; International audience; CONTEXT: Retinol-binding protein 4 (RBP4) may play a role in the development of insulin resistance. OBJECTIVE: We investigated whether RBP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b144fb30bba7b7c3356ed69a8c9bb77
https://pubmed.ncbi.nlm.nih.gov/17405846

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Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats

Autor: Christelle Le Foll, J. Delarue, Mohammed Taouis, Jean-Pascal Bergé, Charlotte Corporeau, Jean-Paul Gouygou

Publikováno v: AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, American Physiological Society, 2006, 290 (1), pp.E78-E86. ⟨10.1152/ajpendo.00200.2005⟩
American Journal of Physiology. Endocrinology and Metabolism (290), E78-E86. (2006)

The present work aimed to study in rats whether substitution of a low level of fish oil (FO; 2.2% of calories) into a low-fat diet (6.6% of calories from fat as peanut-rape oil or control diet) 1) has a tissue-specific effect on insulin signaling pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deb919ceb9ab987b1e30599e181fef6
https://pubmed.ncbi.nlm.nih.gov/16339925

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