pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms

Autor: Frédéric Fischer, Jean-Marc Ghigo, Sylvie Létoffé, Christophe Beloin, David Lebeaux, Ashwini Chauhan, Hilde De Reuse

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 210 (9), pp.1357-1366. ⟨10.1093/infdis/jiu286⟩
Journal of Infectious Diseases, 2014, 210 (9), pp.1357-1366. ⟨10.1093/infdis/jiu286⟩

International audience; BACKGROUND: Limitations in treatment of biofilm-associated bacterial infections are often due to subpopulation of persistent bacteria (persisters) tolerant to high concentrations of antibiotics. Based on the increased aminogly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ab35f0921c96e292014449f0e8fe1
https://pubmed.ncbi.nlm.nih.gov/24837402