pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms

Autor: Frédéric Fischer, Jean-Marc Ghigo, Sylvie Létoffé, Christophe Beloin, David Lebeaux, Ashwini Chauhan, Hilde De Reuse

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 210 (9), pp.1357-1366. ⟨10.1093/infdis/jiu286⟩
Journal of Infectious Diseases, 2014, 210 (9), pp.1357-1366. ⟨10.1093/infdis/jiu286⟩

International audience; BACKGROUND: Limitations in treatment of biofilm-associated bacterial infections are often due to subpopulation of persistent bacteria (persisters) tolerant to high concentrations of antibiotics. Based on the increased aminogly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ab35f0921c96e292014449f0e8fe1
https://pubmed.ncbi.nlm.nih.gov/24837402

Diabetes mellitus, hearing loss, and therapeutic interventions: A systematic review of insights from preclinical animal models.

Autor: Mittal, Rahul^1,2 (AUTHOR) r.mittal11@med.miami.edu, Keith, Grant³ (AUTHOR), Lacey, Mitchel⁴ (AUTHOR), Lemos, Joana R. N.¹ (AUTHOR), Mittal, Jeenu² (AUTHOR), Assayed, Amro¹ (AUTHOR), Hirani, Khemraj¹ (AUTHOR) r.mittal11@med.miami.edu

Publikováno v: PLoS ONE. 7/10/2024, Vol. 19 Issue 7, p1-23. 23p.

Antibiotics, Analgesic Sedatives, and Antiseizure Medications Frequently Used in Critically Ill Neonates: A Narrative Review.

Autor: Kontou, Angeliki, Agakidou, Eleni, Chatziioannidis, Ilias, Chotas, William, Thomaidou, Evanthia, Sarafidis, Kosmas

Publikováno v: Children; Jul2024, Vol. 11 Issue 7, p871, 45p

Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

Autor: Dominique Detaille, Elsa Briones, José M. López-Novoa, Xavier Leverve, Mohamad-Yehia El-Mir, Marta Prieto, Miguel Arévalo, Angel Puente, Ana I. Morales

Publikováno v: Kidney International
Kidney International, Nature Publishing Group, 2010, 77 (10), pp.861-9. ⟨10.1038/ki.2010.11⟩

International audience; The antidiabetic drug metformin can diminish apoptosis induced by oxidative stress in endothelial cells and prevent vascular dysfunction even in nondiabetic patients. Here we tested whether it has a beneficial effect in a rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e057d34f363c20d073647181fe96dd25
https://doi.org/10.1038/ki.2010.11

Histopathological and Ultrastructural Alterations in The Renal Cortex of Albino Mice Foetuses Induced by Beta-Lactam Antibiotic 'Amoxicillin'.

Autor: Sabry, Sahar A.¹ aharsabry84@yahoo.com, Rashad, Heba I.¹, Shahin, Mohamed A.¹

Publikováno v: Egyptian Journal of Hospital Medicine. 10/13/2020, Vol. 81 Issue 7, p2340-2351. 12p.