Zobrazeno 1 - 10
of 66
pro vyhledávání: '"MESH: Gene Rearrangement"'
Autor:
Diane Frankel, Isabelle Nanni, L’Houcine Ouafik, Clara Camilla, Eric Pellegrino, Nathalie Beaufils, Laurent Greillier, Hervé Dutau, Philippe Astoul, Elise Kaspi, Patrice Roll
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10556
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (18), pp.10556. ⟨10.3390/ijms231810556⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (18), pp.10556. ⟨10.3390/ijms231810556⟩
International audience; The detection of ROS1 and ALK rearrangements is performed for advanced-stage non-small cell lung cancer. Several techniques can be used on cytological samples, such as immunocytochemistry (ICC), fluorescence in situ hybridizat
Autor:
Murielle Chauvel, Adeline Feri, Corinne Maufrais, Mélanie Legrand, Christophe d'Enfert, Timea Marton
Publikováno v:
Genetics
Genetics, 2021, 218 (1), pp.iyab028. ⟨10.1093/genetics/iyab028⟩
Genetics, 2021, 218 (1), pp.iyab028. ⟨10.1093/genetics/iyab028⟩
Genomic rearrangements have been associated with the acquisition of adaptive phenotypes, allowing organisms to efficiently generate new favorable genetic combinations. The diploid genome of Candida albicans is highly plastic, displaying numerous geno
Publikováno v:
Therapeutic Advances in Respiratory Disease
Therapeutic Advances in Respiratory Disease, SAGE Publishing, 2019, 13, pp.175346661983190. ⟨10.1177/1753466619831906⟩
Therapeutic Advances in Respiratory Disease, Vol 13 (2019)
Therapeutic Advances in Respiratory Disease, 2019, 13, pp.175346661983190. ⟨10.1177/1753466619831906⟩
Therapeutic Advances in Respiratory Disease, SAGE Publishing, 2019, 13, pp.175346661983190. ⟨10.1177/1753466619831906⟩
Therapeutic Advances in Respiratory Disease, Vol 13 (2019)
Therapeutic Advances in Respiratory Disease, 2019, 13, pp.175346661983190. ⟨10.1177/1753466619831906⟩
International audience; Molecular profiling of metastatic nonsquamous non-small cell lung cancer (NSCLC) is required to guide the treatment strategy. Anaplastic lymphoma kinase ( ALK) gene rearrangements are found in approximately 5% of lung adenocar
Autor:
Maria Mamani-Matsuda, Frédéric Gauthier, Claude-Agnès Reynaud, Corinne Cordier, Capucine Picard, Damiana Lecoeuche, Jean-Claude Weill, Sandra K. Weller
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2008, 205 (6), pp.1331-42. 〈10.1084/jem.20071555〉
Journal of Experimental Medicine, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2008, 205 (6), pp.1331-42. 〈10.1084/jem.20071555〉
Journal of Experimental Medicine, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
International audience; T cell-dependent immune responses develop soon after birth, whereas it takes 2 yr for humans to develop T cell-independent responses. We used this dissociation to analyze the repertoire diversification of IgM(+)IgD(+)CD27(+) B
Autor:
Nicoletta Archidiacono, Jennifer F. Hughes, George M. Weinstock, Yoon Jung, Christopher A. Schmitt, Angela Noll, Nelson B. Freimer, Matthew J. Jorgensen, Jennifer J. Tuscher, Nam Tran, Jason M. Brenchley, David H. O’Connor, Matthew W. Hahn, Eugene Redmond, Alex Nisbett, Roland Zahn, Hannes Svardal, Gary P. Schroth, Raquel García-Pérez, Magnus Nordborg, Nikoleta Juretic, Michael J. Montague, Gregg W.C. Thomas, Michel M. Dione, Julie A. Karl, Anna J. Jasinska, Wesley C. Warren, Jay R. Kaplan, Richard K. Wilson, Patrick Minx, Bronwen Aken, Mariano Rocchi, Colby Chiang, Françoise Thibaud-Nissen, Jessica Wasserscheid, Vasily Ramensky, Oi Wa Choi, Gennady Churakov, Roscoe Stanyon, Yu S. Huang, David Webb, Brian J. Raney, Jörn E. Schmitz, Milinn Kremitzki, Beatrice Jacquelin, Michaela Müller-Trutwin, Juergen Schmitz, Rishi Nag, Tomas Marques-Bonet, LaDeana W. Hillier, Martin Antonio, Tina Graves, Trudy R. Turner, Kim Kyung, Ken Dewar, Chad Tomlinson, Roger W. Wiseman, Oronzo Capozzi
Publikováno v:
Genome Research
Genome Research, Cold Spring Harbor Laboratory Press, 2015, 25 (12), pp.1921-1933. ⟨10.1101/gr.192922.115⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Genome Research, 2015, 25 (12), pp.1921-1933. ⟨10.1101/gr.192922.115⟩
Recercat. Dipósit de la Recerca de Catalunya
Genome research, vol 25, iss 12
Genome Research, Cold Spring Harbor Laboratory Press, 2015, 25 (12), pp.1921-1933. ⟨10.1101/gr.192922.115⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Genome Research, 2015, 25 (12), pp.1921-1933. ⟨10.1101/gr.192922.115⟩
Recercat. Dipósit de la Recerca de Catalunya
Genome research, vol 25, iss 12
Warren, Wesley C. et al.
We describe a genome reference of the African green monkey or vervet (Chlorocebus aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for genetic investigations of simian immunodeficienc
We describe a genome reference of the African green monkey or vervet (Chlorocebus aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for genetic investigations of simian immunodeficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d0aa675f694b3ad60989b91ef45310
https://hal-pasteur.archives-ouvertes.fr/pasteur-01960687/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01960687/document
Autor:
Lionel Le Bourhis, Olivier Lantz, Yue Cui, Katarzyna Franciszkiewicz, Yvonne K. Mburu, Sylvie Rabot, Alexandra Kachaner, Emmanuel Martin, Claire Soudais, Stanislas Mondot, Virginie Premel, Livine Duban, Jean Jaubert, Molly A. Ingersoll, Jean-Pierre de Villartay
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
www.jci.org
Journal of Clinical Investigation, American Society for Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
Journal of Clinical Investigation 11 (125), 4171-4185. (2015)
Journal of Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
www.jci.org
Journal of Clinical Investigation, American Society for Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
Journal of Clinical Investigation 11 (125), 4171-4185. (2015)
Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary conservation of the invariant TCR-alpha chain and restricting molecule MR1, this population is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644f41ebbc4f1764869f11e52b9386a8
https://hal-pasteur.archives-ouvertes.fr/pasteur-01662502/file/JCI82424.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-01662502/file/JCI82424.pdf
Autor:
Christopher McKenzie, Dominique Schneider, Thomas Ferenci, Evelyne Coursange, Joël Gaffé, Ram P. Maharjan
Publikováno v:
Journal of Molecular Evolution
Journal of Molecular Evolution, Springer Verlag, 2011, 72 (4), pp.398-412. ⟨10.1007/s00239-011-9439-2⟩
Journal of Molecular Evolution, Springer Verlag, 2011, 72 (4), pp.398-412. ⟨10.1007/s00239-011-9439-2⟩
International audience; Insertion sequence (IS) elements are present in almost all bacterial genomes and are mobile enough to provide genomic tools to differentiate closely related isolates. They can be used to estimate genetic diversity and identify
Autor:
Yi-Fan Chou, Sandy Chang, Jane A. Skok, Marc Coussens, Ludovic Deriano, Alexander V. Alekseyenko, Asha S. Multani, David Roth, Julie Chaumeil
Publikováno v:
Nature
Nature, Nature Publishing Group, 2011, 471 (7336), pp.119-23. <10.1038/nature09755>
Nature, Nature Publishing Group, 2011, 471 (7336), pp.119-23. ⟨10.1038/nature09755⟩
Nature, Nature Publishing Group, 2011, 471 (7336), pp.119-23. <10.1038/nature09755>
Nature, Nature Publishing Group, 2011, 471 (7336), pp.119-23. ⟨10.1038/nature09755⟩
International audience; Misrepair of DNA double-strand breaks produced by the V(D)J recombinase (the RAG1/RAG2 proteins) at immunoglobulin (Ig) and T cell receptor (Tcr) loci has been implicated in pathogenesis of lymphoid malignancies in humans and
Multiple RNA Surveillance Mechanisms Cooperate to Reduce the Amount of Nonfunctional Igκ Transcripts
Autor:
Guillaume Chemin, Michel Cogné, Aurélien Tinguely, Fabien Lechouane, Sophie Duchez, Laurent Delpy, Christophe Sirac
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Random V(D)J junctions ensure that the diversity of the Ig primary repertoire is adapted to the vast heterogeneity of Ags. In two-thirds of cases, recombination between variable segments induces a frameshift in the open reading frame and generates a
Autor:
Panagiotis Ntziachristos, Ludovic Deriano, David Roth, Iannis Aifantis, Mariann Micsinai, Jane A. Skok, Yuval Kluger, Julie Chaumeil
Publikováno v:
Nature Communications
Nature Communications, 2013, 4, pp.2231. ⟨10.1038/ncomms3231⟩
Nature Communications, Nature Publishing Group, 2013, 4, pp.2231. ⟨10.1038/ncomms3231⟩
NATURE COMMUNICATIONS
Nature communications
Nature Communications, 2013, 4, pp.2231. ⟨10.1038/ncomms3231⟩
Nature Communications, Nature Publishing Group, 2013, 4, pp.2231. ⟨10.1038/ncomms3231⟩
NATURE COMMUNICATIONS
Nature communications
International audience; Tight control of antigen-receptor gene rearrangement is required to preserve genome integrity and prevent the occurrence of leukaemia and lymphoma. Nonetheless, mistakes can happen, leading to the generation of aberrant rearra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2495286ed26dbecf67d525e678232a3
https://hal-pasteur.archives-ouvertes.fr/pasteur-01471697/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01471697/document