Zobrazeno 1 - 10 of 19 pro vyhledávání: '"MESH: Ganglia, Spinal"'
1
SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes
Autor: Christian Njoo, Stefan G. Lechner, Mirko Moroni, Francisco J. Taberner, Faramarz Faghihi, Daniel Rangel Rojas, Thomas Fleming, Alexandra Andrieux, Nitin Agarwal, Gary R. Lewin, Pooja Gupta, Kiran Kumar Bali, Anne Dejean, Esther Herpel, Rohini Kuner, Peter P. Nawroth, Damir Omberbasic
Publikováno v: Neuron
Neuron, 2020, 107 (6), pp.1141-1159.e7. ⟨10.1016/j.neuron.2020.06.037⟩
Neuron, Elsevier, 2020, 107 (6), pp.1141-1159.e7. ⟨10.1016/j.neuron.2020.06.037⟩
International audience; Diabetic peripheral neuropathy (DPN) is a highly frequent and debilitating clinical complication of diabetes that lacks therapies. Cellular oxidative stress regulates post-translational modifications, including SUMOylation. He
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5d4cb795a7249a1ea608f05bd207d5
https://hal-pasteur.archives-ouvertes.fr/pasteur-03234828
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2
Mas-related G protein-coupled receptors (Mrgprs) – Key regulators of neuroimmune interactions
Autor: Lilian Basso, Nicolas Cenac, Nadine Serhan, Nicolas Gaudenzio
Publikováno v: Neuroscience Letters
Neuroscience Letters, Elsevier, 2021, 749, ⟨10.1016/j.neulet.2021.135724⟩
Neuroscience Letters, 2021, 749, pp.135724. ⟨10.1016/j.neulet.2021.135724⟩
International audience; Interplay between physiological systems in the body plays a prominent role in health and disease. At the cellular level, such interplay is orchestrated through the binding of specific ligands to their receptors expressed on ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f9fdf9bdba772b56011ab80dcc466
https://doi.org/10.1016/j.neulet.2021.135724
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3
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity
Autor: Jan Schmoranzer, Jan Walcher, Diana Hoffmann, Gary R. Lewin, Caglar Gök, Valérie Bégay, André Lampe, Edgar Specker, Simone Pifferi, Raluca Fleischer, Cristina Picci, Volker Haucke, Mirko Moroni, Rohini Kuner, Martin Neuenschwander, Kate Poole, Ewan St. John Smith, Liudmila Lapatsina, Kiran Kumar Bali, Johannes Kühnemund, Luc Estebanez, James F.A. Poulet, Christiane Wetzel, Jens Peter von Kries
Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2017, 20 (2), pp.209-218. ⟨10.1038/nn.4454⟩
International audience; The skin is equipped with specialized mechanoreceptors that allow the perception of the slightest brush. Indeed, some mechanoreceptors can detect even nanometer-scale movements. Movement is transformed into electrical signals
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298e67084c80191ac5a7c4bc5ef1271d
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4
Fibroblast growth factor homologous factor 1 (FHF1) is expressed in a subpopulation of calcitonin gene-related peptide-positive nociceptive neurons in the murine dorsal root ganglia
Autor: Jean Valmier, Stéphanie Ventéo, Patrick Carroll, Agnès Fichard-Carroll, Sylvie Puech, Ilana Mechaly, Thomas Hubert, Steeve Bourane
Publikováno v: Journal of Comparative Neurology
Journal of Comparative Neurology, Wiley, 2008, 507 (4), pp.1588-601. ⟨10.1002/cne.21631⟩
International audience; Dorsal root ganglia (DRG) neurons exhibit a wide molecular heterogeneity in relation to the various sensory modalities (mechanoception, thermoception, nociception) that they subserve. Finding markers of subpopulations is an im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071cb829b0fbf14f0102e8b493369dec
https://doi.org/10.1002/cne.21631
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5
Collagen XVI is a neural component of the developing and regenerating dorsal root ganglia extracellular matrix
Autor: Thomas Hubert, Sabine Ratzinger, Susanne Grässel, Sophie Grimal, Ilana Méchaly, Agnès Fichard-Carroll
Publikováno v: Matrix Biology
Matrix Biology, Elsevier, 2007, 26 (3), pp.206-10. ⟨10.1016/j.matbio.2006.10.011⟩
International audience; Collagen XVI is a homotrimeric molecule harbouring similarities to the FACIT (fibril-associated collagens with interrupted triple helices) family of collagens (Grassel et al., 1996). Collagen XVI is expressed in skin and carti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8710ad9a5413d1805f99356d5c1b96f0
https://doi.org/10.1016/j.matbio.2006.10.011
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6
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors
Autor: Weike Lai, Kelen Freitas, Shakir Al Sharari, Christopher I. Richards, M. Imad Damaj, Jaclyn Marcovitz, Michael R. Post, Jean-Sebastien Austin, Sarah C. R. Lummis, Luda Diatchenko, Sarah E Clarke, Ardem Patapoutian, Dennis A. Dougherty, Marshall Devor, Jeffrey S. Mogil, Dmitri V. Zaykin, Eske Kvanner Aasvang, Henry A. Lester, Loren J. Martin, John R. Walker, Walrati Limapichat, William Maixner, Jeff Janes, Reinhard Bittner, Feng Dai, Andrew I. Su, Shad B. Smith, Peter Maxwell Slepian, Jeffrey S. Wieskopf, Jayanti Mathur, Mona Alqazzaz, Samantha K. Segall, Jie Zhang, Uwe Maskos, Ryan M. Drenan, Alexander H. Tuttle, Henrik Kehlet, Inna Belfer, Jean-Pierre Changeux, Robert E. Sorge, Gary D. Slade
Publikováno v: Science Translational Medicine
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (287), pp.287ra72-287ra72. ⟨10.1126/scitranslmed.3009986⟩
Science Translational Medicine, 2015, 7 (287), pp.287ra72-287ra72. ⟨10.1126/scitranslmed.3009986⟩
International audience; Chronic pain is a highly prevalent and poorly managed human health problem. We used microarray-based expression genomics in 25 inbred mouse strains to identify dorsal root ganglion (DRG)-expressed genetic contributors to mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f232e558171d972c48dbfb4909aa91
https://doi.org/10.1126/scitranslmed.3009986
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7
Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons
Autor: Françoise Helmbacher, Yang Liu, Igor M. Samokhvalov, Lise Rodat-Despoix, Patrick Delmas, Eduardo Gascon, Pascale Malapert, Aziz Moqrich, Stéphane Gaillard, Flavio Maina
Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2010, 30 (37), pp.12414-23. ⟨10.1523/JNEUROSCI.3135-10.2010⟩
Journal of Neuroscience, Society for Neuroscience, 2010, 30 (37), pp.12414-23. 〈10.1523/JNEUROSCI.3135-10.2010〉
Journal of Neuroscience, 2010, 30 (37), pp.12414-23. ⟨10.1523/JNEUROSCI.3135-10.2010⟩
Nociceptors in peripheral ganglia display a remarkable functional heterogeneity. They can be divided into the following two major classes: peptidergic and nonpeptidergic neurons. Although RUNX1 has been shown to play a pivotal role in the specificati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5e226e319fa80a3ba534642d970c00
https://hal.archives-ouvertes.fr/hal-00625096
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8
Anti-nociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain
Autor: Juliette Van Steenwinckel, Luc Maroteaux, Nadège Berson, Michel Pohl, Jeremy Truchetto, N. A. Urtikova, Marie Conrath, Stéphane Doly
Publikováno v: PAIN
PAIN, Elsevier, 2012, 153 (6), pp.1320-31. ⟨10.1016/j.pain.2012.03.024⟩
Pain; Vol 153
Pain
Pain, 2012, 153 (6), pp.1320-31. ⟨10.1016/j.pain.2012.03.024⟩
International audience; Serotonin is critically involved in neuropathic pain. However, its role is far from being understood owing to the number of cellular targets and receptor subtypes involved. In a rat model of neuropathic pain evoked by chronic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f35e1d12050bde07e7d2d18cff6e7c
https://hal.archives-ouvertes.fr/hal-01225065/document
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9
Acid-sensing ion channels in postoperative pain
Autor: Emmanuel Deval, Eric Lingueglia, Valérie Friend, Alain Eschalier, Anne Delaunay, Xavier Gasull, Abdelkrim Alloui, Michel Lazdunski, Jacques Noël
Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2011, 31 (16), pp.6059-66. ⟨10.1523/JNEUROSCI.5266-10.2011⟩
Journal of Neuroscience, 2011, 31 (16), pp.6059-66. ⟨10.1523/JNEUROSCI.5266-10.2011⟩
Journal of Neuroscience, Society for Neuroscience, 2011, 31 (16), pp.6059-6066. ⟨10.1523/JNEUROSCI.5266-10.2011⟩
Journal of Neuroscience, 2011, 31 (16), pp.6059-6066. ⟨10.1523/JNEUROSCI.5266-10.2011⟩
Iatrogenic pain consecutive to a large number of surgical procedures has become a growing health concern. The etiology and pathophysiology of postoperative pain are still poorly understood, but hydrogen ions appear to be important in this process. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63fef3027687949d5db21d056edeb5b
https://hal.archives-ouvertes.fr/hal-00731452
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10
Multiple desensitization mechanisms of mechanotransducer channels shape firing of mechanosensory neurons
Autor: Jizhe Hao, Patrick Delmas
Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2010, 30 (40), pp.13384-95. ⟨10.1523/JNEUROSCI.2926-10.2010⟩
Journal of Neuroscience, 2010, 30 (40), pp.13384-95. ⟨10.1523/JNEUROSCI.2926-10.2010⟩
International audience; How desensitization of mechanotransducer currents regulates afferent signal generation in mammalian sensory neurons is essentially unknown. Here, we dissected desensitization mechanisms of mechanotransducer channels in rat sen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24db64af8e19ffa818c09f8c8d222805
https://hal.archives-ouvertes.fr/hal-00625102
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