Zobrazeno 1 - 10
of 39
pro vyhledávání: '"MESH: GTP-Binding Protein alpha Subunits"'
Autor:
Zindel, Diana, Mensat, Patrick, Vol, Claire, Homayed, Zeinab, Charrier-Savournin, Fabienne, Trinquet, Eric, Banères, Jean-Louis, Pin, Jean-Philippe, Pannequin, Julie, Roux, Thomas, Dupuis, Elodie, Prézeau, Laurent, Charrier‐Savournin, Fabienne, Banères, Jean‐Louis, Pin, Jean‐Philippe
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
International audience; The Hippo pathway is an evolutionarily conserved kinase cascade involved in the control of tissue homeostasis, cellular differentiation, proliferation, and organ size, and is regulated by cell-cell contact, apical cell polarit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d116edd5ecc7a3517e908ffca203be02
https://hal.archives-ouvertes.fr/hal-03382626
https://hal.archives-ouvertes.fr/hal-03382626
Autor:
Laura Albizu, Alain Rabié, Thierry Durroux, Bernard Mouillac, Christiane Mendre, Hervé Ansanay, Sanja Perkovska, Hélène Orcel
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2009, 75 (3), pp.637-47. ⟨10.1124/mol.108.049031⟩
Molecular Pharmacology, 2009, 75 (3), pp.637-47. ⟨10.1124/mol.108.049031⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2009, 75 (3), pp.637-47. ⟨10.1124/mol.108.049031⟩
Molecular Pharmacology, 2009, 75 (3), pp.637-47. ⟨10.1124/mol.108.049031⟩
International audience; We show here that the rat vasopressin V(1b) receptor simultaneously activates both the G(q/11)-inositol phosphate (IP) and G(s)-cAMP pathways when transiently expressed in Chinese hamster ovary, human embryonic kidney (HEK) 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d953929474f66909e25b8325fc1436f2
https://doi.org/10.1124/mol.108.049031
https://doi.org/10.1124/mol.108.049031
Autor:
Libé, Rossella, Fratticci, Amato, Lahlou, Najiba, Jornayvaz, François, Tissier, Frédérique, Louiset, Estelle, Guibourdenche, Jean, Vieillefond, Annick, Zerbib, Marc, Bertherat, Jérôme, Libe, R., Jornayvaz, R.
Publikováno v:
Journal of Andrology
Journal of Andrology, American Society of Andrology, 2012, 33 (4), pp.578-584. ⟨10.2164/jandrol.111.013441⟩
Journal of Andrology, American Society of Andrology, 2012, 33 (4), pp.578-584. ⟨10.2164/jandrol.111.013441⟩
International audience; Leydig cell tumors of the testis are the most common type of non-germ cell testicular tumors. In adult patients, gynecomastia, oligozoospermia, erectile dysfunction, and other signs of feminization can be present, whereas test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28684c3022b2a68c3174213a53d4f83
https://doi.org/10.2164/jandrol.111.013441
https://doi.org/10.2164/jandrol.111.013441
Autor:
Jianfeng Liu, Chanjuan Xu, Federica Bertaso, Philippe Rondard, Fangli Cao, Xueying Zhang, Haijun Tu, Jean-Philippe Pin
Publikováno v:
Cellular Signalling
Cellular Signalling, Elsevier, 2007, 19 (9), pp.1996-2002. ⟨10.1016/j.cellsig.2007.05.004⟩
Cellular Signalling, 2007, 19 (9), pp.1996-2002. ⟨10.1016/j.cellsig.2007.05.004⟩
Cellular Signalling, Elsevier, 2007, 19 (9), pp.1996-2002. ⟨10.1016/j.cellsig.2007.05.004⟩
Cellular Signalling, 2007, 19 (9), pp.1996-2002. ⟨10.1016/j.cellsig.2007.05.004⟩
gamma-aminobutyric acid type B (GABA(B)) receptor is an allosteric complex made of two subunits, GABA(B1) and GABA(B2). GABA(B2) plays a major role in the coupling to G protein whereas GABA(B1) binds GABA. It has been shown that GABA(B) receptor acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a59756fac6ff9808e096f44b759e97
https://doi.org/10.1016/j.cellsig.2007.05.004
https://doi.org/10.1016/j.cellsig.2007.05.004
Autor:
Damien Maurel, Michel Fink, Mohammed Akli Ayoub, Laurent Prézeau, Virginie Binet, Hervé Ansanay, Jean-Philippe Pin
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 71 (5), pp.1329-40. ⟨10.1124/mol.106.030304⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 71 (5), pp.1329-40. ⟨10.1124/mol.106.030304⟩
G protein-coupled receptors transmit extracellular signals into the cells by activating heterotrimeric G proteins, a process that is often followed by receptor desensitization. Monitoring such a process in real time and in living cells will help bett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdcd45c6627b36ca2e1aafaf7e12e41
https://doi.org/10.1124/mol.106.030304
https://doi.org/10.1124/mol.106.030304
Autor:
Virginie Steunou, Salah Azzi, Christelle Reynes, Nathalie Sakakini, Anne Barlier, Guiomar Perez de Nanclares, Boris Keren, Caroline Silve, Sandra Chantot, Stéphanie Maupetit-Méhouas, Agnès Linglart, Irene Netchine
Publikováno v:
Human Mutation
Human Mutation, 2013, 34 (8), pp.1172-80. ⟨10.1002/humu.22352⟩
Human Mutation, Wiley, 2013, 34 (8), pp.1172-80. ⟨10.1002/humu.22352⟩
Human Mutation, Wiley, 2013, 34 (8), pp.1172-80. 〈10.1002/humu.22352〉
Human Mutation, 2013, 34 (8), pp.1172-80. ⟨10.1002/humu.22352⟩
Human Mutation, Wiley, 2013, 34 (8), pp.1172-80. ⟨10.1002/humu.22352⟩
Human Mutation, Wiley, 2013, 34 (8), pp.1172-80. 〈10.1002/humu.22352〉
International audience; Most patients with pseudohypoparathyroidism type 1b (PHP-1b) display a loss of imprinting (LOI) encompassing the GNAS locus resulting in PTH resistance. In other imprinting disorders, such as Russell-Silver or Beckwith-Wiedema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eede371a9c3bfb35cacb46601cb4cce
https://hal.science/hal-00966219
https://hal.science/hal-00966219
Autor:
Jean-Louis Banères, Lauriane Onfroy, Jean-Philippe Leyris, Mathieu Maingot, Pascal Verdié, Jean Martinez, Aude Saulière, Céline Galés, Marjorie Damian, Jean-Alain Fehrentz, Céline M'Kadmi, Didier Gagne, Séverine Denoyelle, Jacky Marie, Sophie Mary
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2015, 290 (45), pp.27021-27039. ⟨10.1074/jbc.M115.659250⟩
Journal of Biological Chemistry, 2015, 290 (45), pp.27021-27039. ⟨10.1074/jbc.M115.659250⟩
International audience; The G protein-coupled receptor GHS-R1a mediates ghrelin-induced growth hormone secretion, food intake, and reward-seeking behaviors. GHS-R1a signals through Gq, Gi/o, G13, and arrestin. Biasing GHS-R1a signaling with specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4d0d6af27d5751b836d84dcea5c49e
https://hal.umontpellier.fr/hal-03564155/document
https://hal.umontpellier.fr/hal-03564155/document
Autor:
Cindy Colson, Agnès Linglart, Harald Jüppner, Anne-Claire Brehin, Nicolas Richard, Virginie Grybek, Marie-Laure Kottler, Stéphanie Maupetit-Méhouas
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (4), pp.E623-E631. ⟨10.1210/jc.2014-4047⟩
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (4), pp.E623-E631. ⟨10.1210/jc.2014-4047⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (4), pp.E623-E631. ⟨10.1210/jc.2014-4047⟩
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (4), pp.E623-E631. ⟨10.1210/jc.2014-4047⟩
Context: GNAS is one of few genetic loci that undergo allelic-specific methylation resulting in the parent-specific expression of at least four different transcripts. Due to monoallelic expression, heterozygous GNAS mutations affecting either paterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5522e52d5f70ab9ad643be54139d1a7b
https://hal.archives-ouvertes.fr/hal-02423832
https://hal.archives-ouvertes.fr/hal-02423832
Autor:
Pauline Romanet, Alain Enjalbert, Rachel Reynaud, Lindsay Osei, Morgane Pertuit, Irene Netchine, Anne Barlier
Publikováno v:
Pediatrics
Pediatrics, American Academy of Pediatrics, 2015, 135 (4), pp.e1079-83
Pediatrics, 2015, 135 (4), pp.e1079-83
Pediatrics, American Academy of Pediatrics, 2015, 135 (4), pp.e1079-83
Pediatrics, 2015, 135 (4), pp.e1079-83
International audience; Pseudohypoparathyroidism (PHP) is a group of disorders characterized by end-organ resistance to the parathyroid hormone (PTH). PHP type 1A includes multihormone resistance syndrome, Albright's hereditary osteodystrophy, and ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645d58a5a5136c0da11316901380993e
https://hal.archives-ouvertes.fr/hal-01188625
https://hal.archives-ouvertes.fr/hal-01188625
Autor:
Sylvie Salenave, Jessica Zucman-Rossi, Emmanuelle Jeannot, Gabrielle Couchy, Philippe Chanson, Paulette Bioulac-Sage, Jean-Charles Nault, Charles Balabaud, Marie-José Redon, Camilla Pilati, Sophie Prevot, Marie-Christine Saint-Paul, Philippe Labrune, Jeanne Tran Van Nhieu, Anne de Muret, Monique Fabre, Jean-Yves Scoazec, Catherine Buffet
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2012, 56 (1), pp.184-91. ⟨10.1016/j.jhep.2011.07.018⟩
Journal of Hepatology, 2012, 56 (1), pp.184-91. ⟨10.1016/j.jhep.2011.07.018⟩
Journal of Hepatology, Elsevier, 2012, 56 (1), pp.184-91. 〈10.1016/j.jhep.2011.07.018〉
Journal of Hepatology, Elsevier, 2012, 56 (1), pp.184-91. ⟨10.1016/j.jhep.2011.07.018⟩
Journal of Hepatology, 2012, 56 (1), pp.184-91. ⟨10.1016/j.jhep.2011.07.018⟩
Journal of Hepatology, Elsevier, 2012, 56 (1), pp.184-91. 〈10.1016/j.jhep.2011.07.018〉
Background & Aims Mosaic G-protein alpha-subunit ( GNAS )-activating mutations are responsible for the McCune–Albright (MCA) syndrome. This oncogene that activates the adenylate cyclase is also mutated in various tumor types leading to the accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810622953255cef519dd62654009f363
https://hal.archives-ouvertes.fr/hal-00724895
https://hal.archives-ouvertes.fr/hal-00724895