Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells

Autor: Julia von Blume, Maria Nitti, Stéphanie Lebreton, Dandan Liu, Chiara Zurzolo, Simona Paladino, Paolo Pinton

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proc Natl Acad Sci U S A

International audience; Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are lipid-associated luminal secretory cargoes selectively sorted to the apical surface of the epithelia where they reside and play diverse vital functions. Cholesterol-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1cfa4878e77e0b1d36f0524f7f4ca2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03517396

LC3C Contributes to Vpu-Mediated Antagonism of BST2/Tetherin Restriction on HIV-1 Release through a Non-canonical Autophagy Pathway

Autor: Stéphane Frémont, Aurelia Kuster, Olivier Leymarie, Ursula Madjo, Katy Janvier, Sarah Gallois-Montbrun, Clarisse Berlioz-Torrent, Mélanie Nehlich

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2016, 17 (9), pp.2221-2233. ⟨10.1016/j.celrep.2016.10.045⟩

International audience; BST2 (bone marrow stromal antigen 2)/tetherin is a restriction factor of enveloped viruses, which blocks the release of viral particles. HIV-1 encodes proteins that antagonize this innate barrier, including the accessory prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5542ca7e7c71ac0bf9de4121a4da4df7
https://doi.org/10.1016/j.celrep.2016.10.045

Synergistic inactivation of AXL: a (cross)road to cure ovarian cancer?

Autor: Chiara Zurzolo

Publikováno v: EMBO Reports
EMBO Reports, 2018, 19 (8), pp.e46492. ⟨10.15252/embr.201846492⟩
EMBO Reports, EMBO Press, 2018, 19 (8), pp.e46492. ⟨10.15252/embr.201846492⟩

In ovarian cancer, the prometastatic RTK AXL promotes motility, invasion and poor prognosis. Here, we show that reduced survival caused by AXL overexpression can be mitigated by the expression of the GPI-anchored tumour suppressor OPCML Further, we d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76655fb1496f0c57da314405f66b9ee
https://hal-pasteur.archives-ouvertes.fr/pasteur-02263624

Systematic review: New serological markers (anti-glycan, anti-GP2, anti-GM-CSF Ab) in the prediction of IBD patient outcomes

Autor: Miles P. Sparrow, Xavier Roblin, Chantal Dumestre-Pérard, Melanie Rinaudo-gaujous, Christian Genin, J. Bonneau, Stéphane Paul

Publikováno v: Autoimmunity Reviews
Autoimmunity Reviews, Elsevier, 2015, 14 (3), pp.231-245. ⟨10.1016/j.autrev.2014.11.004⟩

International audience; Traditionally, IBD diagnosis is based on clinical, radiological, endoscopic, and histological criteria. Biomarkers are needed in cases of uncertain diagnosis, or to predict disease course and therapeutic response. No guideline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c841fbe8adc825c6099a1fb2fa2feb9
https://doi.org/10.1016/j.autrev.2014.11.004

Adherent-Invasive E. coli enhances colonic hypersensitivity and P2X receptors expression during post-infectious period

Autor: Frederic A. Carvalho, Agathe Gelot, Nicolas Barnich, Amandine Lashermes, Ludivine Boudieu, Julie Barbier, Benoit Sion, Denis Ardid

Publikováno v: Gut microbes
Gut microbes, Taylor & Francis, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩
Gut microbes, 2017, 9 (1), pp.26-37. ⟨10.1080/19490976.2017.1361091⟩

International audience; Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) are related gastrointestinal disorders characterized by abdominal pain associated with colonic hypersensitivity (CHS). Studies in humans have reported an abno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9298def37614a2830592b09ce901cbf8
https://hal.archives-ouvertes.fr/hal-02064637