Výsledky vyhledávání - "MESH: G2 Phase"

Regulation of ALT-associated homology-directed repair by polyADP-ribosylation

Publikováno v: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol

International audience; The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by poly(ADP-ribose) glycohydrolase (PARG) is essential for progressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d45f0c33f255ca7323659e74359498
https://hal.sorbonne-universite.fr/hal-03138406

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Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages

Autor: Odile Sergent, James J. Pestka, Dominique Lagadic-Gossmann, Kaisa Haglund, Jørn A. Holme, Anita Solhaug, Béatrice Dendelé, Gunnar Sundstøl Eriksen

Publikováno v: Toxicology Letters
Toxicology Letters, 2013, 219 (1), pp.8-17. ⟨10.1016/j.toxlet.2013.02.012⟩
Toxicology Letters, Elsevier, 2013, 219 (1), pp.8-17. ⟨10.1016/j.toxlet.2013.02.012⟩

International audience; The mycotoxin alternariol (AOH), a frequent contaminant in fruit and cereal products, is known to induce DNA damage with subsequent cell cycle arrest. Here we elucidated the effects of AOH on stages of cell cycle progression u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e794c51325f77bda09d87f39d9e3caff
https://doi.org/10.1016/j.toxlet.2013.02.012

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Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle

Autor: Martine Berthelot-Grosjean, Sophie G. Martin

Publikováno v: Nature
Nature, Nature Publishing Group, 2009, 459 (7248), pp.852-6. ⟨10.1038/nature08054⟩

International audience; Cells normally grow to a certain size before they enter mitosis and divide. Entry into mitosis depends on the activity of Cdk1, which is inhibited by the Wee1 kinase and activated by the Cdc25 phosphatase. However, how cells s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e2f1da9988dc1c0d62b6c33bf422f6
https://doi.org/10.1038/nature08054

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Characterization of centrosomal localization and dynamics of Cdc25C phosphatase in mitosis

Autor: May C. Morris, Jerome Bonnet, Peter Coopman

Publikováno v: Cell Cycle
Cell Cycle, Taylor & Francis, 2008, 7 (13), pp.1991-8

International audience; In mammalian cells, three Cdc25 phosphatases A, B, C coordinate cell cycle progression through activating dephosphorylation of Cyclin-dependent kinases. Whereas Cdc25B is believed to trigger entry into mitosis, Cdc25C is thoug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6ecfdd0d4fb84d22b402a91e603138
https://doi.org/10.4161/cc.7.13.6095

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Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2′-deoxycytidine in human leukemic KG1 cells

Autor: Joëlle Riond, Didier Cussac, Lucie Fournier, Florence Busato, Jérome Besse, Cécile Desjobert, Jörg Tost, Sophie Bréand, Stéphane Vispé, Emeline Davoine, Natacha Novosad, Fabrice Lestienne, Luc De Vries, Arthur Deroide, Paola B. Arimondo

Publikováno v: Oncotarget
Oncotarget, Impact journals, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Scopus-Elsevier
Oncotarget, 2015, 6 (17), pp.15265-15282. ⟨10.18632/oncotarget.3317⟩
Europe PubMed Central

// Stephane Vispe 1 , Arthur Deroide 1 , Emeline Davoine 1 , Cecile Desjobert 1 , Fabrice Lestienne 2 , Lucie Fournier 1 , Natacha Novosad 1 , Sophie Breand 3 , Jerome Besse 3 , Florence Busato 4 , Jorg Tost 4 , Luc De Vries 2 , Didier Cussac 2 , Joe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66560f2157e2f74b389fb7912920127c
https://hal-pasteur.archives-ouvertes.fr/pasteur-03043762

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PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase

Autor: Marie-Geneviève Mattei, Cécile Mignon-Ravix, Judith Luciani, Hüseyin Sirma, Anne Moncla, Yves Usson, Jean Feunteun, Danielle Depetris, Michael J. Mitchell, André Mégarbané, Catherine Metzler-Guillemain, Pierre Sarda

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2006, 119 (Pt 12), pp.2518-31. ⟨10.1242/jcs.02965⟩

We have recently demonstrated that heterochromatin HP1 proteins are aberrantly distributed in lymphocytes of patients with immunodeficiency, centromeric instability and facial dysmorphy (ICF) syndrome. The three HP1 proteins accumulate in one giant b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfda3d4ca1d1413280030659f1cea6e4
https://doi.org/10.1242/jcs.02965

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Genotoxic-activated G2-M checkpoint exit is dependent on CDC25B phosphatase expression

Autor: Marie-Christine Brezak, Gregoire Prevost, Béatrix Bugler, Bernard Ducommun, Bernadette Aressy, Muriel Quaranta

Publikováno v: Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2006, 5 (6), pp.1446-51. ⟨10.1158/1535-7163.MCT-06-0099⟩

Cell cycle arrest at the G2-M checkpoint is an essential feature of the mechanisms that preserve genomic integrity. CDC25 phosphatases control cell cycle progression by dephosphorylating and activating cyclin-dependent kinase/cyclin complexes. Their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffe840285622d22875138ab55d19cf7
https://doi.org/10.1158/1535-7163.mct-06-0099

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Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy

Autor: Anastasia R. Goloudina, Elena Y. Kochetkova, Marc Bardou, Arlette Hammann, Oleg N. Demidov, Sarah Richaud, Carmen Garrido, Olga A. Fedorova, Nickolai A. Barlev, Burhan Uyanik, V Clausse

Publikováno v: Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2016, 7 (4), pp.e2195. 〈http://www.nature.com/cddis/journal/v7/n4/full/cddis201696a.html〉. 〈10.1038/cddis.2016.96〉
Cell Death and Disease, Nature Publishing Group, 2016, 7 (4), pp.e2195. ⟨10.1038/cddis.2016.96⟩

Inactivation of p53 found in more than half of human cancers is often associated with increased tumor resistance to anti-cancer therapy. We have previously shown that overexpression of the phosphatase Wip1 in p53-negative tumors sensitizes them to ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c549fa132fd556be508b199e05ea66
http://europepmc.org/articles/PMC4855675

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Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor

Autor: Elisabeth Filipski, Rune Smaaland, Paolo Sassone-Corsi, Teresa G. Granda, Nicolas Cermakian, Francis Lévi, Xu-Hui Liu

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (2), pp.304-6. ⟨10.1096/fj.04-2665fje⟩

International audience; Proapoptotic drugs such as docetaxel displayed least toxicity and highest antitumor efficacy following dosing during the circadian rest phase in mice, suggesting that cell cycle and apoptotic processes could be regulated by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892344840cfce5a824d3daf62624b287
https://doi.org/10.1096/fj.04-2665fje

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Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2–M transition

Autor: Bernard Monsarrat, Gladys Mirey, Nathalie Theis-Febvre, Estelle Schmitt, Stéphanie Dutertre, Carine Froment, Jean-Pierre Bouché, Martine Cazales, Christine Dozier, Bernard Ducommun, Muriel Quaranta, Valerie Trabut, Claude Prigent

Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2004, 117 (Pt 12), pp.2523-31. ⟨10.1242/jcs.01108⟩
Journal of Cell Science, 2004, 117 (Pt 12), pp.2523-31. ⟨10.1242/jcs.01108⟩
Journal of Cell Science 12 (117), 2523-2531. (2004)

Aurora-A protein kinase, which is the product of an oncogene, is required for the assembly of a functional mitotic apparatus and the regulation of cell ploidy. Overexpression of Aurora-A in tumour cells has been correlated with cancer susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff8abee3fecb95f19dbdbaac02ee3e5
https://doi.org/10.1242/jcs.01108

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