Zobrazeno 1 - 10
of 124
pro vyhledávání: '"MESH: Extracellular Matrix"'
Autor:
Josephine Kemna, Evelyne Gout, Leon Daniau, Jessica Lao, Kristoffer Weißert, Sandra Ammann, Ralf Kühn, Matthias Richter, Christine Molenda, Anje Sporbert, Dario Zocholl, Robert Klopfleisch, Hugues Lortat-Jacob, Peter Aichele, Thomas Kammertoens, Thomas Blankenstein
Publikováno v:
Nature Immunology
Nature Immunology, 2023, ⟨10.1038/s41590-023-01420-5⟩
Nature Immunology, 2023, 24 (3), pp.414-422. ⟨10.1038/s41590-023-01420-5⟩
Nature Immunology, 2023, ⟨10.1038/s41590-023-01420-5⟩
Nature Immunology, 2023, 24 (3), pp.414-422. ⟨10.1038/s41590-023-01420-5⟩
Interferon-γ (IFNγ) is an important mediator of cellular immune responses, but high systemic levels of this cytokine are associated with immunopathology. IFNγ binds to its receptor (IFNγR) and to extracellular matrix (ECM) via four positively cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2795f36be82eab84f706e12f7f7bb4
http://edoc.mdc-berlin.de/23037/1/23037oa.pdf
http://edoc.mdc-berlin.de/23037/1/23037oa.pdf
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-5 (2021)
BMC Ophthalmology
BMC Ophthalmology, 2021, 21 (1), pp.35. ⟨10.1186/s12886-021-01802-z⟩
BMC Ophthalmology, BioMed Central, 2021, 21 (1), pp.35. ⟨10.1186/s12886-021-01802-z⟩
BMC Ophthalmology
BMC Ophthalmology, 2021, 21 (1), pp.35. ⟨10.1186/s12886-021-01802-z⟩
BMC Ophthalmology, BioMed Central, 2021, 21 (1), pp.35. ⟨10.1186/s12886-021-01802-z⟩
Background Lipoid proteinosis (LP) is a rare multisystem inherited disease. We report here in three LP cases with beaded papules of the eyelid. Their clinical presentations, histological characteristics, and genetic findings are described and discuss
Autor:
Mohamed Amine Chetoui, Dominique Ambard, Patrick Canãdas, Pascal Kouyoumdjian, Pascale Royer, Simon Le Floc’h
Publikováno v:
Medical Engineering & Physics
Medical Engineering & Physics, 2022, 110, pp.103908. ⟨10.1016/j.medengphy.2022.103908⟩
Medical Engineering & Physics, 2022, 110, pp.103908. ⟨10.1016/j.medengphy.2022.103908⟩
International audience; Current intervertebral disc finite element models are hard to validate since they describe multi-physical phenomena and contain a huge number of material properties. This work aims to simplify numerical validation/identificati
Autor:
Guylène Le Meur, Susanne Roosing, Panagiotis I. Sergouniotis, Marta Corton, Sandro Banfi, Graeme C.M. Black, Ivan Conte, Hélène Naacke, Carmen Ayuso, Christian Hamel, Almudena Avila-Fernandez, Agnès Muller, Guillaume Olivier, Daniela Intartaglia, Claire-Marie Dhaenens, Gaël Manes, Sanne K Verbakel, Jeroen Klevering, Isabelle Meunier, Béatrice Bocquet, Carel B. Hoyng, Agathe Roubertie, Audrey Sénéchal, Xavier Zanlonghi
Publikováno v:
Journal of Medical Genetics
Journal of Medical Genetics, 2021, 58 (8), pp.570-578. ⟨10.1136/jmedgenet-2020-107150⟩
Journal of Medical Genetics, 58, 570-578
Journal of Medical Genetics, 58, 8, pp. 570-578
Journal of Medical Genetics, 2021, 58 (8), pp.570-578. ⟨10.1136/jmedgenet-2020-107150⟩
Journal of Medical Genetics, 58, 570-578
Journal of Medical Genetics, 58, 8, pp. 570-578
BackgroundInherited retinal disorders are a clinically and genetically heterogeneous group of conditions and a major cause of visual impairment. Common disease subtypes include vitelliform macular dystrophy (VMD) and retinitis pigmentosa (RP). Despit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c418790cf0e92ff05817a63ae7d81a9
https://hal.science/hal-03652615
https://hal.science/hal-03652615
Fetal Programming by Methyl Donor Deficiency Produces Pathological Remodeling of the Ascending Aorta
Autor:
Sébastien Blaise, Jean-Louis Guéant, Jean-Michel Camadro, Sébastien Hergalant, Laetitia Vanalderwiert, Rosa-Maria Guéant-Rodriguez, Brittany Balint, Laurent Lignières
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/atvbaha.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/ATVBAHA.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/atvbaha.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/ATVBAHA.120.315587⟩
Objective: Deficiency in vitamin B12/folate (methyl donor deficiency [MDD]) produces cardiovascular outcomes during aging and fetal programming effects in newborns of MDD mothers. Whether fetal programming provokes long-term effects on aorta remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b20e6604bfb390011bfd2b19b3e357
https://hal.archives-ouvertes.fr/hal-03238712
https://hal.archives-ouvertes.fr/hal-03238712
Autor:
Nadine Suffee, Geneviève Marcelin, Emmanuel L. Gautier, Amélie Lacombe, Carla Da Cunha, Isabelle Dugail, Christine Rouault, Nataliya Sokolovska, Karine Clément, Arnaud Leclerc, Camille Gamblin
Publikováno v:
Autophagy
Autophagy, 2020, 16 (12), pp.2156-2166. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, 2020, 16 (12), Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, Taylor & Francis, 2020, Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, 2020, 16 (12), pp.2156-2166. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, 2020, 16 (12), Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, Taylor & Francis, 2020, Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩
International audience; Adipose tissue (AT) fibrosis in obesity compromises adipocyte functions and responses to intervention-induced weight loss. It is driven by AT progenitors with dual fibro/adipogenic potential, but pro-fibrogenic pathways activa
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, 2017, 28 (14), pp.1815-2022. ⟨10.1091/mbc.E17-03-0134⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (14), pp.1815-2022. ⟨10.1091/mbc.E17-03-0134⟩
Molecular Biology of the Cell, 2017, 28 (14), pp.1815-2022. ⟨10.1091/mbc.E17-03-0134⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (14), pp.1815-2022. ⟨10.1091/mbc.E17-03-0134⟩
International audience; Chemical and physical properties of the environment control cell proliferation, differentiation, or apoptosis in the long term. However, to be able to move and migrate through a complex three-dimensional environment, cells mus
Autor:
Akeila Bellahcene, Andrei Turtoi, P. Cusumano, Vincenzo Castronovo, Arnaud Blomme, Olivier Peulen
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2016, 32 (11), pp.1019-1022. ⟨10.1051/medsci/20163211020⟩
médecine/sciences, EDP Sciences, 2016, 32 (11), pp.1019-1022. ⟨10.1051/medsci/20163211020⟩
International audience
Autor:
Cristina Beltrami, Owen J. L. Rackham, Costanza Emanueli, Nithya Devapragash, Wei-Ping Yu, Xi-Ming Sun, Stuart A. Cook, Norbert Hubner, Francesco Pesce, Ee Ling Heng, Elisabeth Tan, Aida Moreno-Moral, Enrique Lara-Pezzi, Gianni D Angelini, Enrico Petretto, Huimei Chen, Paul J.R. Barton, Nathan Harmston, Michal Pravenec, Sebastian Schafer, Maxime Rotival, Nicole Tee, Massimilano Mancini, Leanne E. Felkin, Leonardo Bottolo, Prashant K. Srivastava, Kirill Shkura
Publikováno v:
Nature Communications
Nature Communications, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Chen, H, Moreno-Moral, A, Pesce, F, Devapragash, N, Mancini, M, Heng, E L, Rotival, M, Srivastava, P K, Harmston, N, Shkura, K, Rackham, O J L, Yu, W P, Sun, X M, Tee, N G Z, Tan, E L S, Barton, P J R, Felkin, L E, Lara-Pezzi, E, Angelini, G, Beltrami, C, Pravenec, M, Schafer, S, Bottolo, L, Hubner, N, Emanueli, C, Cook, S A & Petretto, E 2019, ' WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signalling ', Nature Communications, vol. 10, 3616 . https://doi.org/10.1038/s41467-019-11551-9
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Chen, H, Moreno-Moral, A, Pesce, F, Devapragash, N, Mancini, M, Heng, E L, Rotival, M, Srivastava, P K, Harmston, N, Shkura, K, Rackham, O J L, Yu, W P, Sun, X M, Tee, N G Z, Tan, E L S, Barton, P J R, Felkin, L E, Lara-Pezzi, E, Angelini, G, Beltrami, C, Pravenec, M, Schafer, S, Bottolo, L, Hubner, N, Emanueli, C, Cook, S A & Petretto, E 2019, ' WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signalling ', Nature Communications, vol. 10, 3616 . https://doi.org/10.1038/s41467-019-11551-9
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
Cardiac fibrosis is a final common pathology in inherited and acquired heart diseases that causes cardiac electrical and pump failure. Here, we use systems genetics to identify a pro-fibrotic gene network in the diseased heart and show that this netw
Autor:
Christian Dani, A. Remaury, Jean Galitzky, Y. Veeranagouda, A. Briot, Anne Bouloumié, David Estève, M. Didier, Pauline Decaunes, Séverine Ledoux, Nathalie Boulet, Alexia Zakaroff-Girard, C. Belles, Jean-Claude Guillemot
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.2549. ⟨10.1038/s41467-019-09992-3⟩
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.2549. ⟨10.1038/s41467-019-09992-3⟩
Human adipose tissue (hAT) is constituted of structural units termed lobules, the organization of which remains to be defined. Here we report that lobules are composed of two extracellular matrix compartments, i.e., septa and stroma, delineating nich