Zobrazeno 1 - 10
of 51
pro vyhledávání: '"MESH: Excitatory Amino Acid Agonists"'
Autor:
Delphine Rigault, Francine Acher, Nadia Oueslati, Hervé Daniel, Marianne Amalric, Isabelle Brabet, Jean-Philippe Pin, Heather McLean, Hugues-Olivier Bertrand, Tiphanie Courtiol, Bruno Vilar, Thomas Bessiron, Cyril Goudet, Thierry Deltheil
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. 〈10.1096/fj.11-195941〉
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. 〈10.1096/fj.11-195941〉
International audience; Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective ligands, but pure agonists still have strong therapeutic potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8983843f27bc58d9bb94a0657cb437b2
https://ora.ox.ac.uk/objects/uuid:ef698f81-75c9-4a7c-865a-379868656d73
https://ora.ox.ac.uk/objects/uuid:ef698f81-75c9-4a7c-865a-379868656d73
Autor:
Hervé Castel, Omar Touzani, Denis Vivien, Eric Maubert, Karim Benchenane, Carine Ali, François Dauphin, Véronique Agin, Michel Boulouard, Robert Dantzer, José P. López-Atalaya, Sabrina Butt-Gueulle, Benoit D. Roussel, R. M. Bluthe, Mónica Fernández-Monreal
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2007, 120 (Pt 4), pp.578-85. 〈10.1242/jcs.03354〉
Journal of Cell Science, Company of Biologists, 2007, 120 (Pt 4), pp.578-585. ⟨10.1242/jcs.03354⟩
Journal of Cell Science, Company of Biologists, 2007, 120 (Pt 4), pp.578-85. 〈10.1242/jcs.03354〉
Journal of Cell Science, Company of Biologists, 2007, 120 (Pt 4), pp.578-585. ⟨10.1242/jcs.03354⟩
International audience; Fine-tuning of NMDA glutamatergic receptor signalling strategically controls crucial brain functions. This process depends on several ligands and modulators, one of which unexpectedly includes the serine protease tissue-type p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607a15d8b363effd0f2fd5547248dee3
https://doi.org/10.1242/jcs.03354
https://doi.org/10.1242/jcs.03354
Publikováno v:
Journal of Neurochemistry
Journal of Neurochemistry, Wiley, 2009, 109 (3), pp.819-25. ⟨10.1111/j.1471-4159.2009.06022.x⟩
Journal of Neurochemistry, Wiley, 2009, 109 (3), pp.819-25. ⟨10.1111/j.1471-4159.2009.06022.x⟩
J. Neurochem. (2009) 109, 819–825. Abstract Controversial debates still remain around the nature of the etiologic agent responsible for Amyotrophic lateral sclerosis/Parkinson dementia complex (ALS/PDC) whose incidence is unusually high among the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14307c1b1c9e5ab88f9c96355008dee2
https://doi.org/10.1111/j.1471-4159.2009.06022.x
https://doi.org/10.1111/j.1471-4159.2009.06022.x
Publikováno v:
Hearing Research
Hearing Research, Elsevier, 2007, 227 (1-2), pp.19-27. ⟨10.1016/j.heares.2006.08.017⟩
Hearing Research, Elsevier, 2007, 227 (1-2), pp.19-27. ⟨10.1016/j.heares.2006.08.017⟩
This report summarizes recent neuropharmacological data at the IHC afferent/efferent synaptic complex: the type of Glu receptors and transporter involved and the modulation of this fast synaptic transmission by the lateral efferents. Neuropharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a5c1b406bc70df242d2ee1ff419756
https://doi.org/10.1016/j.heares.2006.08.017
https://doi.org/10.1016/j.heares.2006.08.017
Autor:
Pierre Gressens, Isabelle Husson, Muriel Jaquet, Jacques Mallet, Barry E. Kosofsky, Alexis-Pierre Bemelmans
Publikováno v:
Journal of Neuroscience Research
Journal of Neuroscience Research, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Journal of Neuroscience Research, Wiley, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Journal of Neuroscience Research, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Journal of Neuroscience Research, Wiley, 2006, 83 (1), pp.50-60. ⟨10.1002/jnr.20704⟩
Excitotoxicity may be a critical factor in the formation of brain lesions associated with cerebral palsy. When injected into the murine neopallium at postnatal day 5, the glutamatergic analog N-methyl-D-aspartate (NMDA) produces transcortical neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96df00671c709ea24f6cbd2d8d7ffae0
https://doi.org/10.1002/jnr.20704
https://doi.org/10.1002/jnr.20704
Publikováno v:
Neuropharmacology
Neuropharmacology, 2004, 47, pp.333-41. ⟨10.1016/j.neuropharm.2004.05.003⟩
Neuropharmacology, Elsevier, 2004, 47, pp.333-41. ⟨10.1016/j.neuropharm.2004.05.003⟩
Neuropharmacology, 2004, 47, pp.333-41. ⟨10.1016/j.neuropharm.2004.05.003⟩
Neuropharmacology, Elsevier, 2004, 47, pp.333-41. ⟨10.1016/j.neuropharm.2004.05.003⟩
We analyzed the subtypes of group III metabotropic glutamate receptors (mGluRs) modulating inhibitory and excitatory transmission in the rat supraoptic nucleus. Bath application of the agonist l-AP4 at 200 microM, a concentration that activates all g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700ad8275b2441d745b8a506266d68fa
https://doi.org/10.1016/j.neuropharm.2004.05.003
https://doi.org/10.1016/j.neuropharm.2004.05.003
Autor:
Laurent Aniksztejn, Michael Demarque, Hélène Becq, Jean-Bernard Manent, Nathalie Villeneuve, Yehezkel Ben-Ari, Alfonso Represa
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2004, 24 (13), pp.3289-94. ⟨10.1523/JNEUROSCI.5338-03.2004⟩
Journal of Neuroscience, Society for Neuroscience, 2004, 24 (13), pp.3289-94. ⟨10.1523/JNEUROSCI.5338-03.2004⟩
Glutamate transporters are operative at an early developmental stage well before synapse formation, but their functional significance has not been determined. We now report that blockade of glutamate transporters in the immature neocortex generates r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83556f9d9f7af1a1c0fbee257de1795b
https://doi.org/10.1523/jneurosci.5338-03.2004
https://doi.org/10.1523/jneurosci.5338-03.2004
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2001, 292, pp.923-6. ⟨10.1126/science.1059162⟩
Science, American Association for the Advancement of Science (AAAS), 2001, 292, pp.923-6. ⟨10.1126/science.1059162⟩
Science, American Association for the Advancement of Science, 2001, 292, pp.923-6. ⟨10.1126/science.1059162⟩
Science, American Association for the Advancement of Science (AAAS), 2001, 292, pp.923-6. ⟨10.1126/science.1059162⟩
Analysis of excitatory synaptic transmission in the rat hypothalamic supraoptic nucleus revealed that glutamate clearance and, as a consequence, glutamate concentration and diffusion in the extracellular space, is associated with the degree of astroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b723c5d8a3831581b35613fec89113c7
https://doi.org/10.1126/science.1059162
https://doi.org/10.1126/science.1059162
Publikováno v:
Neurochirurgie
Neurochirurgie, Elsevier Masson, 2008, 54 (3), pp.135-40. ⟨10.1016/j.neuchi.2008.02.002⟩
Neuro-Chirurgie
Neuro-Chirurgie, 2008, 54 (3), pp.135-40. 〈10.1016/j.neuchi.2008.02.002〉
Neurochirurgie, Elsevier Masson, 2008, 54 (3), pp.135-40. ⟨10.1016/j.neuchi.2008.02.002⟩
Neuro-Chirurgie
Neuro-Chirurgie, 2008, 54 (3), pp.135-40. 〈10.1016/j.neuchi.2008.02.002〉
International audience; Drug-resistant mesial temporal lobe epilepsy with hippocampal sclerosis is associated with anatomical, ultrastructural and functional changes that facilitate generation and spread of epileptic seizures. Intrahippocampal circui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ecce3a961b2c5af945f6c381d004e69
https://www.hal.inserm.fr/inserm-00410611
https://www.hal.inserm.fr/inserm-00410611
Autor:
Fernando Kasanetz, Véronique Deroche-Gamonet, P-V Piazza, Nadège Berson, Eric Balado, Mathieu Lafourcade, J-F Fiancette, P Renault, J-M Revest, Olivier J. Manzoni
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2013, 18 (6), pp.729-737. ⟨10.1038/mp.2012.59⟩
Molecular Psychiatry, Nature Publishing Group, 2013, 18 (6), pp.729-737. ⟨10.1038/mp.2012.59⟩
International audience; Defining the drug-induced neuroadaptations specifically associated with the behavioral manifestation of addiction is a daunting task. To address this issue, we used a behavioral model that differentiates rats controlling their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be29652b22d47b18bd5937d25aa8bfd5
https://hal.archives-ouvertes.fr/hal-02325894
https://hal.archives-ouvertes.fr/hal-02325894