Epac in cardiac calcium signaling

Autor: Anna Llach, Jean-Pierre Benitah, Alejandro Domínguez-Rodríguez, Frank Lezoualc'h, Eric Morel, Gema Ruiz-Hurtado, Ana María Gómez

Publikováno v: Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2013, 58, pp.162-71. ⟨10.1016/j.yjmcc.2012.11.021⟩
Journal of Molecular and Cellular Cardiology, 2013, 58, pp.162-71. ⟨10.1016/j.yjmcc.2012.11.021⟩

Epac, exchange protein directly activated by cAMP, is emerging as a new regulator of cardiac physiopathology. Although its effects are much less known than the classical cAMP effector, PKA, several studies have investigated the cardiac role of Epac,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf0b409d7219220a7c812d123bc1f6a
https://doi.org/10.1016/j.yjmcc.2012.11.021

Role of smooth muscle cell mineralocorticoid receptor in vascular tone

Autor: Carlos Labat, Soumaya El Moghrabi, Frederic Jaisser, Guillaume Galmiche, Ekaterina Belozertseva, Antoine Tarjus, Huguette Louis, Patrick Lacolley

Publikováno v: Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag (Germany), 2015, 467 (8), pp.1643-1650. ⟨10.1007/s00424-014-1616-x⟩
Pflügers Archiv European Journal of Physiology, 2015, 467 (8), pp.1643-1650. ⟨10.1007/s00424-014-1616-x⟩
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2015, 467 (8), pp.1643-1650. ⟨10.1007/s00424-014-1616-x⟩

International audience; Identification of the mineralocorticoid receptor (MR) in the vasculature (i.e., endothelial and smooth muscle cells) raised the question of its role in vascular function and blood pressure control. Using a mouse model with con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a943ecb4b4a1866c851b0f0b5bd7a4a2
https://hal.univ-lorraine.fr/hal-01758570

ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction.: Molecular effects of delapril on cardiomyocytes

Autor: Zalvidea, Santiago, Andre, Lucas, Loyer, Xavier, Cassan, Cécile, Sainte-Marie, Yannis, Thireau, Jérôme, Sjaastad, Ivar, Heymes, Christophe, Pasquié, Jean-Luc, Cazorla, Olivier, Aimond, Franck, Richard, Sylvain

Publikováno v: Current Molecular Medicine
Current Molecular Medicine, Bentham Science Publishers, 2012, 12 (2), pp.206-17. ⟨10.2174/156652412798889045⟩

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::014e8fc7a970c944ca71c53e99e2fc19
https://www.hal.inserm.fr/inserm-00665476/file/CMM_Zalvidea_19Nov2011_Auteur.pdf

ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction. : Molecular effects of delapril on cardiomyocytes

Autor: Christophe Heymes, Lucas Andre, Ivar Sjaastad, Cécile Cassan, Franck Aimond, Sylvain Richard, Jean-Luc Pasquié, Yannis Sainte-Marie, Olivier Cazorla, Jérôme Thireau, Santiago Zalvidea, Xavier Loyer

Publikováno v: ResearcherID
Current Molecular Medicine
Current Molecular Medicine, Bentham Science Publishers, 2012, 12 (2), pp.206-17

International audience; Prevention of adverse cardiac remodeling after myocardial infarction (MI) remains a therapeutic challenge. Angiotensin-converting enzyme inhibitors (ACE-I) are a well-established first-line treatment. ACE-I delay fibrosis, but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303493c25a055722a20c24e26cc6623b
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000300638600010&KeyUID=WOS:000300638600010