Evaluation of a novel therapeutic education programme for people with alcohol use disorder in France: a mixed-methods intervention study protocol (ETHER)

Autor: Antwerpes, Saskia, Costa, Marie, Coste, Marion, Bureau, Morgane, Maradan, Gwenaelle, Cutarella, Christophe, Leloutre, Jacques, Riccobono-Soulier, Olivier, Hedoire, Sophie, Frot, Elodie, Vernier, Fabienne, Vassas-Goyard, Stéphanie, Barré, Tangui, Casanova, Danielle, Carrieri, Patrizia

Publikováno v: Harm Reduction Journal
Harm Reduction Journal, 2022, 19 (1), pp.2. ⟨10.1186/s12954-021-00587-0⟩
Harm Reduction Journal, Vol 19, Iss 1, Pp 1-13 (2022)

Background ETHER (“Education THEérapeutique pour la Réduction des dommages en alcoologie” or Therapeutic education for alcohol-related harm reduction) is a multicentre community-based mixed-methods study, which aims to evaluate the effectivenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b39a57e1d0b6def6dc09c9dde7664834
https://www.hal.inserm.fr/inserm-04044071/document

Kv1.1 channels act as mechanical brake in the senses of touch and pain

Autor: Jizhe Hao, Florian Lesage, Catharina Lavebratt, Patrick Delmas, Françoise Padilla, Jacques Noël, Mathieu Dandonneau

Publikováno v: Neuron
Neuron, Elsevier, 2013, 77 (5), pp.899-914. ⟨10.1016/j.neuron.2012.12.035⟩
Neuron, 2013, 77 (5), pp.899-914. ⟨10.1016/j.neuron.2012.12.035⟩

International audience; Molecular determinants of threshold sensitivity of mammalian mechanoreceptors are unknown. Here, we identify a mechanosensitive (MS) K(+) current (IKmech) that governs mechanical threshold and adaptation of distinct population

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89f3809efabd48bbc2d0d2625f41200
https://hal.archives-ouvertes.fr/hal-00855028

Discovery and Pharmacological Profile of New 1H‑Indazole-3- carboxamide and 2H‑Pyrrolo[3,4‑c]quinoline Derivatives as SelectiveSerotonin 4 Receptor Ligands

Autor: Guido Furlotti, Magaro' Gabriele, Gaetano Miele, Maria Alessandra Alisi, Roberta Costi, Federica Rosi, Beatrice Garrone, Claudia Apicella, Giuliana Cuzzucoli Crucitti, Luca Pescatori, Lorenzo Polenzani, Nicola Cazzolla, Roberto Di Santo, Giorgina Mangano, Rosella Ombrato, Marco Vitiello, Alberto Iacovo, Alessandra Capezzone de Joannon

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (22), pp.9446-66. ⟨10.1021/jm300573d⟩

International audience; Since the discovery of the serotonin 4 receptor (5-HT(4)R), a large number of receptor ligands have been studied. The safety concerns and the lack of market success of these ligands have mainly been attributed to their lack of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27830a121d88f8c84057f71256da0e4b
http://hdl.handle.net/11573/488191

Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures.: Characterizing novel KCNH2 mutations

Autor: Keller, Dagmar, Grenier, Julie, Christé, Georges, Dubouloz, Frédérique, Osswald, Stephan, Brink, Marijke, Ficker, Eckhard, Chahine, Mohamed

Publikováno v: Canadian Journal of Cardiology
Canadian Journal of Cardiology, Elsevier, 2009, 25 (8), pp.455-62

International audience; BACKGROUND: Long QT syndrome (LQTS) is characterized by corrected QT interval prolongation leading to torsades de pointes and sudden cardiac death. LQTS type 2 (LQTS2) is caused by mutations in the KCNH2 gene, leading to a red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::d5bbc6cd72c5503f3c1b252050476c2f
https://www.hal.inserm.fr/inserm-00409709/file/Keller-D_2009_Can_J_Cardiol.pdf

Symptom and quality of life results of an international randomised phase III study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer

Autor: Giuseppe Giaccone, C. Debruyne, Michael Millward, Corneel Coens, G. D'Addario, Petr Zatloukal, Lisa S. Rome, Enriqueta Felip, Luc Thiberville, Andrew Bottomley

Publikováno v: European Journal of Cancer
European Journal of Cancer, Elsevier, 2008, 44 (15), pp.2178-84. ⟨10.1016/j.ejca.2008.06.036⟩
European Journal of Cancer, 2008, 44 (15), pp.2178-84. ⟨10.1016/j.ejca.2008.06.036⟩

Aims: This study reports the symptom and HRQOL results in which standard treatment was compared to standard therapy plus Bec2, an anti-idiotypic antibody that mimics GD3, a ganglioside antigen. Methods: Five hundred and fifteen LD SCLC patients were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed2e16d1736c694749d8e64803adc3b
https://www.hal.inserm.fr/inserm-00467793