Zobrazeno 1 - 10
of 76
pro vyhledávání: '"MESH: Estrogen Receptor alpha"'
Autor:
Gagniac, Laurine, Rusidzé, Mariam, Boudou, Frederic, Cagnet, Stephanie, Adlanmerini, Marine, Jeannot, Pauline, Gaide, Nicolas, Giton, Frank, Besson, Arnaud, Weyl, Ariane, Gourdy, Pierre, Raymond-Letron, Isabelle, Arnal, Jean-Francois, Brisken, Cathrin, Lenfant, Francoise
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2020, 147 (5), pp.dev182303. ⟨10.1242/dev.182303⟩
Development (Cambridge, England), Company of Biologists, 2020, 147 (5), pp.dev182303. ⟨10.1242/dev.182303⟩
17β-Estradiol induces the postnatal development of mammary gland and influences breast carcinogenesis by binding to the estrogen receptor ERα. ERα acts as a transcription factor but also elicits rapid signaling through a fraction of ERα expressed
Autor:
Marie-Laure Ancelin, Pierre-Yves Scarabin, Isabelle Carrière, Karen Ritchie, Olivier Rouaud, Joanne Ryan, Karine Pérès, Jacqueline Scali
Publikováno v:
Journal of Affective Disorders
Journal of Affective Disorders, Elsevier, 2012, 136 (3), pp.1222-6. ⟨10.1016/j.jad.2011.10.010⟩
Journal of Affective Disorders, Elsevier, 2012, 136 (3), pp.1222-6. ⟨10.1016/j.jad.2011.10.010⟩
International audience; BACKGROUND: Despite evidence of estrogen's mood-enhancing effects, the association between estrogen receptor (ER) gene variants and lifetime major depression has been insufficiently studied. METHODS: 3987 community-dwelling wo
Autor:
Patrick Balaguer, Jean-Marc Porcher, Selim Ait-Aissa, François Brion, Farzad Pakdel, Emmanuelle Maillot-Marechal, Anne Cosnefroy
Publikováno v:
Toxicological Sciences
Toxicological Sciences, 2012, 125 (2), pp.439-49. ⟨10.1093/toxsci/kfr297⟩
Toxicological Sciences, Oxford University Press (OUP), 2012, 125 (2), pp.439-49. ⟨10.1093/toxsci/kfr297⟩
Toxicological Sciences, 2012, 125 (2), pp.439-49. ⟨10.1093/toxsci/kfr297⟩
Toxicological Sciences, Oxford University Press (OUP), 2012, 125 (2), pp.439-49. ⟨10.1093/toxsci/kfr297⟩
International audience; The number of environmental chemical contaminants suspected to act as endocrine disruptor compounds by interacting with estrogen receptor (ER) signaling pathway has been continuously increasing. To study such interaction, the
Autor:
Frédéric Percevault, Christophe Tiffoche, Gilles Flouriot, Guillaume Huet, Farzad Pakdel, Jean-François Arnal, Raphaël Métivier, Noureddine Boujrad, Yohann Mérot
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (49), pp.33729-39. ⟨10.1074/jbc.M109.045534⟩
Journal of Biological Chemistry, 2009, 284 (49), pp.33729-39. ⟨10.1074/jbc.M109.045534⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (49), pp.33729-39. ⟨10.1074/jbc.M109.045534⟩
Journal of Biological Chemistry, 2009, 284 (49), pp.33729-39. ⟨10.1074/jbc.M109.045534⟩
International audience; Although involved in processes leading to the emergence and development of hormone-dependent breast cancers, the estrogen receptor alpha (ERalpha) also prevents transformed cells from progressing toward a more aggressive pheno
Autor:
José-Manuel Molina-Molina, Vincent Cavaillès, Patrick Balaguer, Elena Gomez, Nicolás Olea, Selim Ait-Aissa, Arnaud Pillon, Aurélie Escande, Farzad Pakdel
Publikováno v:
Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, 2008, 232 (3), pp.384-95. ⟨10.1016/j.taap.2008.07.017⟩
Toxicology and Applied Pharmacology, Elsevier, 2008, 232 (3), pp.384-95. ⟨10.1016/j.taap.2008.07.017⟩
Toxicology and Applied Pharmacology, 2008, 232 (3), pp.384-95. ⟨10.1016/j.taap.2008.07.017⟩
Toxicology and Applied Pharmacology, Elsevier, 2008, 232 (3), pp.384-95. ⟨10.1016/j.taap.2008.07.017⟩
International audience; Benzophenone (BP) derivatives, BP1 (2,4-dihydroxybenzophenone), BP2 (2,2',4,4'-tetrahydroxybenzophenone), BP3 (2-hydroxy-4-methoxybenzophenone), and THB (2,4,4'-trihydroxybenzophenone) are UV-absorbing chemicals widely used in
Autor:
M. Jeyakumar, Anick Auger, Dino Moras, Sylvie Mader, Elise Hébert, Mathieu Lupien, Khalid Hilmi, Geneviève Anne Pinard, David Cotnoir-White, Jean Marie Wurtz, John A. Katzenellenbogen, Guila Dayan, Caroline Loch
Publikováno v:
Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2007, 21 (4), pp.797-816. ⟨10.1210/me.2006-0074⟩
Molecular Endocrinology-Baltimore-, Endocrine Society, 2007, 21 (4), pp.797-816. ⟨10.1210/me.2006-0074⟩
The basis for the differential repressive effects of antiestrogens on transactivation by estrogen receptor-α (ERα) remains incompletely understood. Here, we show that the full antiestrogen ICI182,780 and, to a lesser extent, the selective ER modula
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (7), pp.2196-201. ⟨10.1073/pnas.0510974103⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (7), pp.2196-201. ⟨10.1073/pnas.0510974103⟩
Estradiol is a major regulator of postnatal mammary gland development and thought to exert its effects through estrogen receptor α (ERα) expressed in the mammary gland stroma and epithelium. Previous studies, however, were confounded by the use of
Autor:
Li, X.-G., Okada, T., Kodera, M., Nara, Y., Takino, N., Muramatsu, C., Ikeguchi, K., Urano, F., Ichinose, Hiroshi, Metzger, D., Chambon, P., Nakano, I., Ozawa, K., Muramatsu, S.-I.
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2006, 13 (1), pp.160-6. ⟨10.1016/j.ymthe.2005.08.009⟩
Molecular Therapy, Nature Publishing Group, 2006, 13 (1), pp.160-6. ⟨10.1016/j.ymthe.2005.08.009⟩
Molecular Therapy, Cell Press, 2006, 13 (1), pp.160-6. ⟨10.1016/j.ymthe.2005.08.009⟩
Molecular Therapy, Nature Publishing Group, 2006, 13 (1), pp.160-6. ⟨10.1016/j.ymthe.2005.08.009⟩
International audience; Regulation of gene expression is necessary to avoid possible adverse effects of gene therapy due to excess synthesis of transgene products. To reduce transgene expression, we developed a viral vector-mediated somatic regulatio
Autor:
Yohann Mérot, Edith Debroas, François Ferrière, Gilles Flouriot, Christian Saligaut, Dominique Duval
Publikováno v:
Journal of Molecular Endocrinology
Journal of Molecular Endocrinology, BioScientifica, 2005, 35 (2), pp.257-67. ⟨10.1677/jme.1.01826⟩
Journal of Molecular Endocrinology, BioScientifica, 2005, 35, pp.257-267
Journal of Molecular Endocrinology, 2005, 35 (2), pp.257-67. ⟨10.1677/jme.1.01826⟩
Journal of Molecular Endocrinology, BioScientifica, 2005, 35 (2), pp.257-67. ⟨10.1677/jme.1.01826⟩
Journal of Molecular Endocrinology, BioScientifica, 2005, 35, pp.257-267
Journal of Molecular Endocrinology, 2005, 35 (2), pp.257-67. ⟨10.1677/jme.1.01826⟩
Numerous studies, both in vivo and in vitro, have reported neuronal differentiating and neuroprotective actions of estrogens. Most of these estrogenic effects are mediated through specific receptors termed estrogen receptors. The aim of this study wa
Autor:
Raphaël Métivier, Lindsay M. Hill, Mara T. Mashek, Christopher C. Valley, Elaine T. Alarid, Amy M. Fowler, Natalia M. Solodin
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (13), pp.5417-28. ⟨10.1128/MCB.25.13.5417-5428.2005⟩
Molecular and Cellular Biology, 2005, 25 (13), pp.5417-28. ⟨10.1128/MCB.25.13.5417-5428.2005⟩
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (13), pp.5417-28. ⟨10.1128/MCB.25.13.5417-5428.2005⟩
Molecular and Cellular Biology, 2005, 25 (13), pp.5417-28. ⟨10.1128/MCB.25.13.5417-5428.2005⟩
International audience; The ubiquitin-proteasome pathway has emerged as an important regulatory mechanism governing the activity of several transcription factors. While estrogen receptor alpha (ERalpha) is also subjected to rapid ubiquitin-proteasome