Zobrazeno 1 - 10 of 15 pro vyhledávání: '"MESH: ErbB Receptors"'
1
Phase II study evaluating the association of gemcitabine, trastuzumab and erlotinib as first‐line treatment in patients with metastatic pancreatic adenocarcinoma ( GATE 1)
Autor: Caroline Mollevi, Marc Ychou, Hélène de Forges, Fabienne Portales, Thomas Walter, Catherine Lombard-Bohas, Laurent Mineur, Emmanuelle Samalin, Thibaut Mazard, Eric Assenat, Marie Dupuy, Evelyne Lopez-Crapez, Alexandre Ho-Pun-Cheung, Florence Boissière-Michot
Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (3), pp.682-691. ⟨10.1002/ijc.33225⟩
International audience; In a previous phase II study (THERAPY), cetuximab and trastuzumab combination, as second-line after progression with gemcitabine, showed disease stabilization in 27% of 33 patients with pancreatic carcinoma. In the present pha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d22e7a47f1fac4149eece0399f76367
https://hal.archives-ouvertes.fr/hal-03670041
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2
EGFR gene amplification in monocentric and multicentric glioblastoma
Autor: Didier Dormont, Marc Sanson, Lucia Nichelli, Anna Luisa Di Stefano
Publikováno v: Journal of Neuro-Oncology
Journal of Neuro-Oncology, 2019, 145 (3), pp.587-589. ⟨10.1007/s11060-019-03324-7⟩
Journal of Neuro-Oncology, Springer Verlag, 2019, 145 (3), pp.587-589. ⟨10.1007/s11060-019-03324-7⟩
International audience
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b326a8fec548b472ba96cfcf564d42
https://hal.science/hal-03139280
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4
Awareness of cervical cancer among women attending an HIV treatment centre: a cross-sectional study from Morocco
Autor: Herfs, Michaël, Roncarati, Patrick, Koopmansch, Benjamin, Peulen, Olivier, Bruyère, Diane, Lebeau, Alizee, Hendrick, Elodie, Hubert, Pascale, Poncin, Aurelie, Penny, William, Piazzon, Nathalie, Monnien, Franck, Guenat, David, Mougin, Christiane, Pretet, Jean-Luc, Vuitton, Lucine, Segers, Karin, Lambert, Frédéric, Bours, Vincent, De Leval, Laurence, Valmary-Degano, Severine, Quick, Charles, Crum, Christopher, Delvenne, Philippe
Publikováno v: BMJ Open
BMJ Open, BMJ Publishing Group, 2018, 8 (8), pp.e020343. ⟨10.1136/bmjopen-2017-020343⟩
ObjectiveTo explore awareness about cervical cancer among Moroccan women attending an HIV treatment centre in Laâyoune city, Morocco.DesignA cross-sectional study was conducted from April to June 2017 using a knowledge test regarding cervical cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d9ddc69755f7cea10eae150622aab4
https://hal.archives-ouvertes.fr/hal-01889887
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5
LKB1 as a Gatekeeper of Hepatocyte Proliferation and Genomic Integrity during Liver Regeneration
Autor: Maillet, Vanessa, Boussetta, Nadia, Leclerc, Jocelyne, Fauveau, Veronique, Foretz, Marc, Viollet, Benoit, Couty, Jean-Pierre, Celton-Morizur, Séverine, Perret, Christine, Desdouets, Chantal
Publikováno v: Cell Reports
Cell Reports, 2018, 22 (8), pp.1994-2005. ⟨10.1016/j.celrep.2018.01.086⟩
Cell Reports, Vol 22, Iss 8, Pp 1994-2005 (2018)
Cell Reports, Elsevier Inc, 2018, 22 (8), pp.1994-2005. ⟨10.1016/j.celrep.2018.01.086⟩
Comment inLKB1: Controlling Quiescence and Genomic Integrity at Home. [Trends Endocrinol Metab. 2018]; International audience; Liver kinase B1 (LKB1) is involved in several biological processes and is a key regulator of hepatic metabolism and polarit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e0d478ae2b31ecbe8fb8ff802d1e329
https://www.hal.inserm.fr/inserm-02349915/document
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6
FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer
Autor: Vincent Denis, Christel Larbouret, Laetitia K. Linares, Esther Pérez-Gracia, Delphine Desigaud, Adeline Ayrolles-Torro, Nadia Vie, M. del Rio, Marta Jarlier, Clara Montagut, Diego Tosi, E W-F Lam, Laetitia Marzi, Mar Iglesias, Céline Gongora, Pierre Martineau, Eve Combes
Publikováno v: British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2016, 115 (10), pp.1223-1233. ⟨10.1038/bjc.2016.313⟩
BACKGROUND: Cetuximab, a monoclonal antibody against EGFR used for the treatment of colorectal cancer (CRC), is ineffective in many patients. The aim of this study was to identify the signalling pathways activated by cetuximab in CRC cells and define
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4579077d1c4aa1c4faf7dd0c8990a4d2
https://www.hal.inserm.fr/inserm-02465222
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7
Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3
Autor: Nicolas Richard, Pierre Hainaut, Bruno Coudert, Xavier Sastre-Garau, Jean-Luc Prétet, Yves-Marie ROBIN, Christos Chouaid, Stefan Michiels, Pierre-Emmanuel Falcoz, Pascal Reynier, Marie Wislez, CHRISTIANE MOUGIN, Patrice VIENS, Helene Blons, Isabelle Borget, Jean-Pierre PIGNON, Denis MORO-SIBILOT, Ivan Bieche
Publikováno v: European Respiratory Journal
European Respiratory Journal, European Respiratory Society, 2011, 39 (1), pp.172-179. ⟨10.1183/09031936.00201210⟩
European Respiratory Journal, 2011, 39 (1), pp.172-179. ⟨10.1183/09031936.00201210⟩
International audience; Several clinical and biological parameters are known to influence the efficacy of second-line erlotinib therapy for nonsmall cell lung cancer (NSCLC), but their medico-economic impact has not been evaluated. The objective of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f5eae2bc2e2807c6c6f6ffd4b48081
https://doi.org/10.1183/09031936.00201210
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8
Helicobacter pylori Activates Matrix Metalloproteinase 10 in Gastric Epithelial Cells via EGFR and ERK-mediated Pathways
Autor: Dionyssios N. Sgouras, Manuel A. S. Santos, Rui M. Ferreira, Ceu Figueiredo, Ioanna S. Sougleri, Ines Pinto-Ribeiro, Maria José Oliveira, Angela M. Costa, Laura Carreto, Fátima Carneiro, Marina S. Leite
Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2016, 213 (11), pp.1767-1776. ⟨10.1093/infdis/jiw031⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International audience; Helicobacter pylori colonizes the human stomach and increases the risk for peptic ulcer disease and gastric carcinoma. H. pylori upregulates the expression and activity of several matrix metalloproteinases (MMPs) in cell lines
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e95c01af718c57672a4a8421afa6bc
https://pubmed.ncbi.nlm.nih.gov/26802142
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9
HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies
Autor: Brunella Costanza, P Meunier, Philippe Delvenne, Akeila Bellahcene, Vincent Hennequière, Pamela Maris, Sara Rezzola, Ana Palacios, Roberto Ronca, Paul Peixoto, Laurent Schoysman, Andrei Turtoi, Arnaud Blomme, Vincenzo Castronovo, Nicolas Goffart, Elettra Bianchi, Aurélie Henry, Robert N. Muller, Bernard Rogister, Sébastien Boutry, E Di Valentin, Olivier Peulen
Publikováno v: Oncogene
Oncogene, Nature Publishing Group, 2016, 35 (34), pp.4481-4494. ⟨10.1038/onc.2015.506⟩
International audience; To date, the mutational status of EGFR and PTEN has been shown as relevant for favoring pro- or anti-tumor functions of STAT3 in human glioblastoma multiforme (GBM). We have screened genomic data from 154 patients and have ide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff5cb94e95794e8a300c948d8451910
https://pubmed.ncbi.nlm.nih.gov/26853466
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10
CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium
Autor: Nathalie Coolen, Virginie Prulière-Escabasse, Pierre-Régis Burgel, Daniel Dusser, Estelle Escudier, André Coste, Yongzheng Wu, Isabelle Fajac, Lhousseine Touqui, Guiti Thévenot, Clémence Martin, Jean-François Papon
Publikováno v: European Respiratory Journal
European Respiratory Journal, European Respiratory Society, 2013, 42 (6), pp.1553-1562. ⟨10.1183/09031936.00164212⟩
European Respiratory Journal, 2013, 42 (6), pp.1553-1562. ⟨10.1183/09031936.00164212⟩
International audience; Peribronchial angiogenesis may occur in cystic fibrosis and vascular endothelial growth factor (VEGF)-A regulates angiogenesis in airways. Peribronchial vascularity and VEGF-A expression were examined using immunocytochemistry
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d50404e016d01b07c398643e380311
https://pubmed.ncbi.nlm.nih.gov/24293414
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