Zobrazeno 1 - 4
of 4
pro vyhledávání: '"MESH: Enzyme Inhibitors/chemistry"'
Autor:
Julie Paoletti, Gilles Labesse, Olivier Dussurget, Marie Anne Nahori, Liliane Assairi, Sylvie Pochet, Muriel Gelin, Valérie Huteau
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2016, 124, pp.1041-1056. ⟨10.1016/j.ejmech.2016.10.033⟩
European Journal of Medicinal Chemistry, 2016, 124, pp.1041-1056. ⟨10.1016/j.ejmech.2016.10.033⟩
European Journal of Medicinal Chemistry, Elsevier, 2016, 124, pp.1041-1056. ⟨10.1016/j.ejmech.2016.10.033⟩
European Journal of Medicinal Chemistry, 2016, 124, pp.1041-1056. ⟨10.1016/j.ejmech.2016.10.033⟩
Increased resistance of pathogens to existing antibiotics necessitates the search for novel targets to develop potent antimicrobials. Biosynthetic pathways of several cofactors important for bacterial growth, such as nicotinamide adenine dinucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e165d3eae566bd9b213507978bbd048a
https://doi.org/10.1016/j.ejmech.2016.10.033
https://doi.org/10.1016/j.ejmech.2016.10.033
Autor:
Roberta Mazzone, Piero Picci, Katia Scotlandi, Michela Pasello, Patrizia Nanni, Giordano Nicoletti, Maria Cristina Manara, Antonello Mai, Clara Guerzoni, Camilla Cristalli, Pier Luigi Lollini, Lorena Landuzzi, Sergio Valente, Giulia Stazi, Paola B. Arimondo, Clemens Zwergel
Publikováno v:
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
The identification of new therapeutic strategies against osteosarcoma, the most common primary bone tumor, continues to be a primary goal to improve the outcomes of patients refractory to conventional chemotherapy. Osteosarcoma originates from the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55d5482d55dc2ed43ad6818ec4cbf60
https://hal.archives-ouvertes.fr/hal-02383680
https://hal.archives-ouvertes.fr/hal-02383680
Autor:
François-Xavier Cantrelle, Jamal Khalife, Isabelle Landrieu, Alain Martoriati, Katia Cailliau-Maggio, Jérôme Vicogne, Aline Fréville, Géraldine Tellier, Christine Pierrot, Audrey Vandomme
Publikováno v:
FEBS Journal
FEBS Journal, Wiley, 2014, 281 (19), pp.4519-4534. ⟨10.1111/febs.12960⟩
FEBS Journal, 2014, 281 (19), pp.4519-4534. ⟨10.1111/febs.12960⟩
FEBS Journal, Wiley, 2014, 281 (19), pp.4519-4534. ⟨10.1111/febs.12960⟩
FEBS Journal, 2014, 281 (19), pp.4519-4534. ⟨10.1111/febs.12960⟩
The regulation of Plasmodium falciparum protein phosphatase type 1 (PfPP1) activity remains to be deciphered. Data from homologous eukaryotic type 1 protein phosphatases (PP1) suggest that several protein regulators should be involved in this essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7ae8399958cd3d07fc17449374a761
https://hal.archives-ouvertes.fr/hal-01077866
https://hal.archives-ouvertes.fr/hal-01077866
Publikováno v:
Combinatorial Chemistry and High Throughput Screening
Combinatorial Chemistry and High Throughput Screening, Bentham Science Publishers, 2008, 11 (4), pp.294-303. ⟨10.2174/138620708784246013⟩
Combinatorial Chemistry and High Throughput Screening, Bentham Science Publishers, 2008, 11 (4), pp.294-303. ⟨10.2174/138620708784246013⟩
International audience; Many natural privileged scaffolds contain a basic nitrogen atom, which often is a key element of pharmacophore and a chemically reactive centre as well. In our ongoing research program devoted to the design of targeted librari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6840fe29a6a3836e04bec860073bd74e
https://doi.org/10.2174/138620708784246013
https://doi.org/10.2174/138620708784246013