Zobrazeno 1 - 10
of 11
pro vyhledávání: '"MESH: Entropy"'
Publikováno v:
Journal of Physical Chemistry B
Journal of Physical Chemistry B, American Chemical Society, 2019, 123 (51), pp.10904-10914. ⟨10.1021/acs.jpcb.9b08470⟩
Journal of Physical Chemistry B, American Chemical Society, 2019, 123 (51), pp.10904-10914. ⟨10.1021/acs.jpcb.9b08470⟩
International audience; Intercalation into DNA is the interaction mode of some anthracycline antibiotics. Recently, the molecular mechanism of this process was explored using the static free energy landscape. Here we explore the dynamical effects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8119698aad4aa54c77ca6761d041f5a0
https://doi.org/10.1021/acs.jpcb.9b08470
https://doi.org/10.1021/acs.jpcb.9b08470
Publikováno v:
Physical Review E
Physical Review E, 2018, 98 (1), pp.012402. ⟨10.1103/PhysRevE.98.012402⟩
Physical Review E, American Physical Society (APS), 2018, 98 (1), pp.012402. ⟨10.1103/PhysRevE.98.012402⟩
Physical Review E, 2018, 98 (1), pp.012402. ⟨10.1103/PhysRevE.98.012402⟩
Physical Review E, American Physical Society (APS), 2018, 98 (1), pp.012402. ⟨10.1103/PhysRevE.98.012402⟩
Maximum Entropy models can be inferred from large data-sets to uncover how collective dynamics emerge from local interactions. Here, such models are employed to investigate neurons recorded by multielectrode arrays in the human and monkey cortex. Tak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10049fa04b86c17c250bb08bf2b2dd55
https://pubmed.ncbi.nlm.nih.gov/30110850
https://pubmed.ncbi.nlm.nih.gov/30110850
Autor:
Thierry Mora, Michael J. Berry, Dario Amodei, Gašper Tkačik, Olivier Marre, William Bialek, Stephanie E. Palmer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (37), pp.11508-11513. ⟨10.1073/pnas.1514188112⟩
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (37), pp.11508-11513. ⟨10.1073/pnas.1514188112⟩
International audience; The activity of a neural network is defined by patterns of spiking and silence from the individual neurons. Because spikes are (relatively) sparse, patterns of activity with increasing numbers of spikes are less probable, but,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dc436adf2e9330c14c71289990145e
https://pubmed.ncbi.nlm.nih.gov/26330611
https://pubmed.ncbi.nlm.nih.gov/26330611
Autor:
Jerome S. Pinkner, Rémi Fronzes, Francesca Gubellini, Parveen Goyal, Petya V. Krasteva, Han Remaut, Imke Van den Broeck, Gérard Pehau-Arnaudet, Matthew George Chapman, Scott J. Hultgren, Anastassia Troupiotis-Tsaïlaki, Wim Jonckheere, Nani Van Gerven, Stefan Howorka
Publikováno v:
Nature
Nature, 2014, 516 (7530), pp.250-253. ⟨10.1038/nature13768⟩
Nature, Nature Publishing Group, 2014, 516 (7530), pp.250-253. ⟨10.1038/nature13768⟩
Nature, 2014, 516 (7530), pp.250-253. ⟨10.1038/nature13768⟩
Nature, Nature Publishing Group, 2014, 516 (7530), pp.250-253. ⟨10.1038/nature13768⟩
International audience; Curli are functional amyloid fibres that constitute the major protein component of the extracellular matrix in pellicle biofilms formed by Bacteroidetes and Proteobacteria (predominantly of the α and γ classes). They provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e45d376845ad19a23502e54373d6ff9
https://hal-pasteur.archives-ouvertes.fr/pasteur-03262663
https://hal-pasteur.archives-ouvertes.fr/pasteur-03262663
Publikováno v:
Neural Computation
Neural Computation, 2013, 25 (7), pp.1661-1692. ⟨10.1162/NECO_a_00463⟩
Neural Computation, 2013, 25 (7), pp.1661-1692. ⟨10.1162/NECO_a_00463⟩
Models of neural responses to stimuli with complex spatiotemporal correlation structure often assume that neurons are only selective for a small number of linear projections of a potentially high-dimensional input. Here we explore recent modeling app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665fcf4e4944041bd836cb68f576abe9
https://pubmed.ncbi.nlm.nih.gov/23607557
https://pubmed.ncbi.nlm.nih.gov/23607557
Autor:
Åke Engström, Jakob Dogan, Per Jemth, Stefano Gianni, Serena Rinaldo, Patrik Lundström, Francesca Cutruzzolà, Celestine N. Chi, S. Raza Haq
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2012, 51 (44), pp.8971-9. ⟨10.1021/bi300792h⟩
Biochemistry, American Chemical Society, 2012, 51 (44), pp.8971-9. ⟨10.1021/bi300792h⟩
The postsynaptic density protein-95/discs large/zonula occludens-1 (PDZ) domain is a protein-protein interaction module with a shallow binding groove where protein ligands bind. However, interactions that are not part of this canonical binding groove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f6e9456ab06c4c6aba15e4d3d5da8b
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-186213
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-186213
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10410 (2010)
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10410. ⟨10.1371/journal.pone.0010410⟩
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10410. ⟨10.1371/journal.pone.0010410⟩
International audience; BACKGROUND: Protein fold recognition usually relies on a statistical model of each fold; each model is constructed from an ensemble of natural sequences belonging to that fold. A complementary strategy may be to employ sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6c32bee0edab9c1ccf018b6ff38fc5
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463972/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20463972/?tool=EBI
Autor:
Daniele Sciretti, Marco Pretti, Alfonso Jaramillo, Alessandro Pelizzola, Pierpaolo Bruscolini
Publikováno v:
Proteins-Structure, Function and Bioinformatics
Proteins-Structure, Function and Bioinformatics, Wiley, 2009, 74 (1), pp.176-91. ⟨10.1002/prot.22145⟩
Proteins-Structure, Function and Bioinformatics, Wiley, 2009, 74 (1), pp.176-91. ⟨10.1002/prot.22145⟩
International audience; Recent advances in modeling protein structures at the atomic level have made it possible to tackle "de novo" computational protein design. Most procedures are based on combinatorial optimization using a scoring function that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c90af8cbf6ab238f107857d80d3a096
https://pubmed.ncbi.nlm.nih.gov/18618711
https://pubmed.ncbi.nlm.nih.gov/18618711
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Public Library of Science, 2008, 4 (3), pp.e1000011. ⟨10.1371/journal.pcbi.1000011⟩
PLoS Computational Biology, Vol 4, Iss 3, p e1000011 (2008)
PLoS Computational Biology, 2008, 4 (3), pp.e1000011. ⟨10.1371/journal.pcbi.1000011⟩
PLoS Computational Biology, Public Library of Science, 2008, 4 (3), pp.e1000011. ⟨10.1371/journal.pcbi.1000011⟩
PLoS Computational Biology, Vol 4, Iss 3, p e1000011 (2008)
PLoS Computational Biology, 2008, 4 (3), pp.e1000011. ⟨10.1371/journal.pcbi.1000011⟩
Most mammalian genes are able to express several splice variants in a phenomenon known as alternative splicing. Serious alterations of alternative splicing occur in cancer tissues, leading to expression of multiple aberrant splice forms. Most studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b798bd5814e25ccbfa6cda81c57a42
https://hal.archives-ouvertes.fr/hal-00286322/file/pcbi.1000011.pdf
https://hal.archives-ouvertes.fr/hal-00286322/file/pcbi.1000011.pdf
Autor:
Shinji Hourai, Natacha Rochel, Dino Moras, Antonio Rumbo, Antonio Mouriño, Xenxo Pérez-García
Publikováno v:
Archives of Biochemistry and Biophysics
Archives of Biochemistry and Biophysics, Elsevier, 2007, 460 (2), pp.172-6. ⟨10.1016/j.abb.2007.01.031⟩
Archives of Biochemistry and Biophysics, Elsevier, 2007, 460 (2), pp.172-6. ⟨10.1016/j.abb.2007.01.031⟩
The crystal structures of vitamin D nuclear receptor (VDR) have revealed that all compounds are anchored by the same residues to the ligand binding pocket (LBP). Based on this observation, a synthetic analog with a locked side chain (21-nor-calcitrio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a320bbe322fd6043fc8bc6ac697877c
https://pubmed.ncbi.nlm.nih.gov/17346665
https://pubmed.ncbi.nlm.nih.gov/17346665