Breakthroughs in medicinal chemistry: new targets and mechanisms, new drugs, new hopes-7

Autor: Gütschow, Michael, Eynde, Jean Jacques Vanden, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino, Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter, Reynisson, Jóhannes, Rapposelli, Simona, Galdiero, Stefania, Winum, Jean-Yves, Brullo, Chiara, Prokai-Tatrai, Katalin, Sharma, Arun, Schapira, Matthieu, Azuma, Yasu-Taka, Cerchia, Laura, Spetea, Mariana, Torri, Giangiacomo, Collina, Simona, Geronikaki, Athina, García-Sosa, Alfonso, Vasconcelos, M Helena, Sousa, Maria Emília, Kosalec, Ivan, Tuccinardi, Tiziano, Duarte, Iola, Salvador, Jorge, Bertinaria, Massimo, Pellecchia, Maurizio, Amato, Jussara, Rastelli, Giulio, Gomes, Paula, Guedes, Rita, Sabatier, Jean-Marc, Estévez-Braun, Ana, Pagano, Bruno, Mangani, Stefano, Ragno, Rino, Kokotos, George, Brindisi, Margherita, González, Florenci, Borges, Fernanda, Miloso, Mariarosaria, Rautio, Jarkko, Muñoz-Torrero, Diego, Vanden Eynde, Jean Jacques, Vasconcelos, M. Helena

Publikováno v: Molecules
Molecules, MDPI, 2020, 25 (13), pp.2968. ⟨10.3390/molecules25132968⟩
Molecules, Vol 25, Iss 2968, p 2968 (2020)
Dipòsit Digital de la UB
Universidad de Barcelona
Molecules (Basel, Online) 25 (2020). doi:10.3390/molecules25132968
info:cnr-pdr/source/autori:Gutschow M.; Eynde J.J.V.; Jampilek J.; Kang C.; Mangoni A.A.; Fossa P.; Karaman R.; Trabocchi A.; Scott P.J.H.; Reynisson J.; Rapposelli S.; Galdier S.; Winum J.-Y.; Brullo C.; Prokai-Tatrai K.; Sharma A.K.; Schapira M.; Azuma Y.-T.; Cerchia L.; Spete M.; Torri G.; Collina S.; Geronikaki A.; Garcia-Sosa A.T.; Helena Vasconcelos M.; Sousa M.E.; Kosalec I.; Tuccinardi T.; Duarte I.F.; Salvador J.A.R.; Bertinaria M.; Pellecchia M.; Amato J.; Rastelli G.; Gomes P.A.C.; Guedes R.C.; Sabatier J.-M.; Estevez-Braun A.; Pagano B.; Mangani S.; Ragno R.; Kokotos G.; Brindisi M.; Gonzalez F.V.; Borges F.; Miloso M.; Rautio J.; Munoz-Torrero D./titolo:Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7/doi:10.3390%2Fmolecules25132968/rivista:Molecules (Basel, Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:25
Molecules, 2020, 25 (13), pp.2968. ⟨10.3390/molecules25132968⟩
Repositori Universitat Jaume I
Universitat Jaume I

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules. In these edito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e417a8ae7bdaece7cdb0a324d6fe2a63
http://hdl.handle.net/11573/1511684

From genomics to metabolomics, moving toward an integrated strategy for the discovery of fungal secondary metabolites

Autor: Isabelle P. Oswald, Emilien L. Jamin, Thaïs Hautbergue, Olivier Puel, Laurent Debrauwer

Publikováno v: Natural Product Reports
Natural Product Reports, Royal Society of Chemistry, 2018, 35 (2), pp.147-173. ⟨10.1039/c7np00032d⟩
Natural Product Reports, 2018, 35 (2), pp.147-173. ⟨10.1039/c7np00032d⟩

International audience; Fungal secondary metabolites are defined by bioactive properties that ensure adaptation of the fungus to its environment. Although some of these natural products are promising sources of new lead compounds especially for the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488311aeb48b0d66affe18db74ac609d
https://doi.org/10.1039/c7np00032d

Developments in SPR Fragment Screening

Autor: Martine Pugnière, Alain Chavanieu

Publikováno v: Expert Opinion on Drug Discovery
Expert Opinion on Drug Discovery, Informa Healthcare, 2016, 11 (5), pp.489-499. ⟨10.1517/17460441.2016.1160888⟩

International audience; INTRODUCTION:Fragment-based approaches have played an increasing role alongside high-throughput screening in drug discovery for 15 years. The label-free biosensor technology based on surface plasmon resonance (SPR) is now sens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854830771cf620a9a98155ac63b32265
https://doi.org/10.1517/17460441.2016.1160888

Microbial-derived products as potential new antimicrobials

Autor: Bruce S. Seal, Djamel Drider, Brian B. Oakley, Harald Brüssow, David Bikard, Joseph O. Rich, Stefan Miller, Estelle Devillard, Jason Kwan, Gérard Bertin, Stuart Reeves, Steven M. Swift, Margot Raicek, Cyril G. Gay

Publikováno v: Veterinary Research
Veterinary Research, BioMed Central, 2018, 49 (1), pp.66. ⟨10.1186/s13567-018-0563-5⟩
Veterinary Research, 2018, 49 (1), pp.66. ⟨10.1186/s13567-018-0563-5⟩
Veterinary Research, Vol 49, Iss 1, Pp 1-12 (2018)

International audience; Due to the continuing global concerns involving antibiotic resistance, there is a need for scientific forums to assess advancements in the development of antimicrobials and their alternatives that might reduce development and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9a5c1cc7b60f2c1b78df82284a3d6e
https://doi.org/10.1186/s13567-018-0563-5

The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery

Autor: Eric Prina, Najma Rachidi, Gerald F. Späth, Suzanne Lamotte

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2017, 11 (6), pp.e0005480. ⟨10.1371/journal.pntd.0005480⟩
PLOS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 2017, 11 (6), pp.e0005480. ⟨10.1371/journal.pntd.0005480⟩
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005480 (2017)

International audience; The state of antileishmanial chemotherapy is strongly compromised by the emergence of drug-resistant Leishmania. The evolution of drug-resistant phenotypes has been linked to the parasites’ intrinsic genome instability, with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547b6df90b34fd156ee577c323382b33
https://hal-pasteur.archives-ouvertes.fr/pasteur-01570238/document