Výsledky vyhledávání - "MESH: Dizocilpine Maleate"

β-N-methylamino-l-alanine inducedin vivoretinal cell death

Autor: Joëlle Chabry, Nicole Zsürger, Serena Santucci

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, Wiley, 2009, 109 (3), pp.819-25. ⟨10.1111/j.1471-4159.2009.06022.x⟩

J. Neurochem. (2009) 109, 819–825. Abstract Controversial debates still remain around the nature of the etiologic agent responsible for Amyotrophic lateral sclerosis/Parkinson dementia complex (ALS/PDC) whose incidence is unusually high among the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14307c1b1c9e5ab88f9c96355008dee2
https://doi.org/10.1111/j.1471-4159.2009.06022.x

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Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11

Autor: Alain Privat, Marisa Teigell, D. Vandame, G. Desmadryl, N. Crouzin, Hélène Hirbec, Alain Buisson, J. Becerril Ortega

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, 2007, 103 (4), pp.1682-96. ⟨10.1111/j.1471-4159.2007.04925.x⟩
Journal of Neurochemistry, Wiley, 2007, 103 (4), pp.1682-96. ⟨10.1111/j.1471-4159.2007.04925.x⟩
Journal of Neurochemistry, Wiley, 2007, 103 (4), pp.1682-96. 〈10.1111/j.1471-4159.2007.04925.x〉

International audience; Over-stimulation of NMDA receptors (NMDARs) is involved in many neurodegenerative disorders. Thus, developing safe NMDAR antagonists is of high therapeutic interest. GK11 is a high affinity uncompetitive NMDAR antagonist with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110861e274abfa453138f9c81ee26a48
https://doi.org/10.1111/j.1471-4159.2007.04925.x

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Forelimb dyskinesia mediated by high-frequency stimulation of the subthalamic nucleus is linked to rapid activation of the NR2B subunit of N-methyl-D-aspartate receptors

Autor: Quintana, A., Melon, C., Kerkerian-Le Goff, L., Salin, P., Savasta, M., Sgambato-Faure, V.

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2010, 32 (3), pp.423-34. ⟨10.1111/j.1460-9568.2010.07290.x⟩
European Journal of Neuroscience, 2010, 32 (3), pp.423-34. ⟨10.1111/j.1460-9568.2010.07290.x⟩

International audience; Dyskinesia is a major side-effect of chronic l-DOPA administration, the reference treatment for Parkinson's disease. High-frequency stimulation of the subthalamic nucleus (STN-HFS) alleviates parkinsonian motor symptoms and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d9a8b8651e1e9435a3f6798a962fa3cd
https://www.hal.inserm.fr/inserm-00627991/document

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Selection of two lines of mice based on latency to onset of methionine sulfoximine seizures

Autor: Tobias Hévor, Zahir Tahi, Benoît Martin, Jean-François Cloix

Publikováno v: Epilepsia
Epilepsia, 2010, 51 (1), pp.118-28. ⟨10.1111/j.1528-1167.2009.02200.x⟩
Epilepsia, Wiley, 2010, 51 (1), pp.118-28. ⟨10.1111/j.1528-1167.2009.02200.x⟩

Summary Purpose: In various animals methionine sulfoximine (MSO) induces tonic–clonic seizures resembling the most striking form of human epilepsies. The aim of the present study was to select two lines of mice based upon differences in their laten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbb069827e5f5cd4744562bcf104238
https://hal.science/hal-00911553

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NMDA receptor hypofunction leads to generalized and persistent aberrant gamma oscillations independent of hyperlocomotion and the state of consciousness

Autor: Julien Gaudias, Elena Tolmacheva, Nigel C. Jones, Terence J. O'Brien, Michael R. Salzberg, Tahir Hakami, Didier Pinault, Jospeh Chaumont

Publikováno v: PLoS ONE, Vol 4, Iss 8, p e6755 (2009)
PLoS ONE
PLoS ONE, Public Library of Science, 2009, 4 (8), pp.e6755. ⟨10.1371/journal.pone.0006755⟩

BACKGROUND: The psychotomimetics ketamine and MK-801, non-competitive NMDA receptor (NMDAr) antagonists, induce cognitive impairment and aggravate schizophrenia symptoms. In conscious rats, they produce an abnormal behavior associated with a peculiar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49baa02e41ae79949c1d98b7ffd3960f
http://europepmc.org/articles/PMC2727800?pdf=render

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Post-pubertal emergence of alterations in locomotor activity in stop null mice

Autor: Annie Andrieux, Jean-Baptiste Bertrand, Thierry d'Amato, Didier Job, Marie-Françoise Suaud-Chagny, Mélina Bégou, Philippe Brun, Annie Schweitzer, Mohamed Saoud

Publikováno v: Synapse
Synapse, Wiley-Blackwell, 2007, 61 (9), pp.689-97. ⟨10.1002/syn.20409⟩
Synapse, 2007, 61 (9), pp.689-97. ⟨10.1002/syn.20409⟩
Synapse / Synapse (Hoboken)
Synapse / Synapse (Hoboken), 2007, 61 (9), pp.689-97. ⟨10.1002/syn.20409⟩

International audience; Overt schizophrenia is preceded by a prodromal phase during which juvenile patients display attenuated schizophrenia-related symptoms. Here, we have looked for evidence of a prodromal phase in juvenile STOP null mice, which, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc9a22de84abb2ff45030c914d277d4
https://www.hal.inserm.fr/inserm-00379954/document

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A noncanonical release of GABA and glutamate modulates neuronal migration

Autor: Isabel Jorquera, Alfonso Represa, Laurent Aniksztejn, Yehezkel Ben-Ari, Christophe Pellegrino, Michael Demarque, Jean-Bernard Manent

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2005, 25 (19), pp.4755-65. ⟨10.1523/JNEUROSCI.0553-05.2005⟩

Immature neurons express GABA and glutamate receptors before synapse formation, and both transmitters are released at an early developmental stage. We have now tested the hypothesis that the ongoing release of GABA and glutamate modulates neuronal mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae08bfc7c5adb10ddf002e2ba624f340
https://www.hal.inserm.fr/inserm-00484364/document

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Glutamate receptor antagonists and benzodiazepine inhibit the progression of granule cell dispersion in a mouse model of mesial temporal lobe epilepsy

Autor: Koichi Mitsuya, Kiyoshi Kurokawa, Antoine Depaulis, Any Boehrer, Masayuki Matsuda, Christophe Heinrich, Fumio Suzuki

Publikováno v: Epilepsia
Epilepsia, Wiley, 2005, 46 (2), pp.193-202. ⟨10.1111/j.0013-9580.2005.35504.x⟩

Summary: Purpose: Unilateral intrahippocampal injection of kainic acid (KA) in adult mice induces the progressive dispersion of dentate granule cells, one of the characteristic pathologic changes of mesial temporal lobe epilepsy. However, little is k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755aa5ae7cc07c849580c73d4d380eb5
https://pubmed.ncbi.nlm.nih.gov/16499777

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