Relative diabetogenic properties of islet-specific Tc1 and Tc2 cells in immunocompetent hosts

Autor: Nadège Bercovici, Karine Goude, Christophe Combadière, Karine Bailly, Roland S. Liblau, Nathalie Pardigon, Csaba Vizler, Agnès Heurtier

Publikováno v: Journal of Immunology
Journal of Immunology, 2000, 165 (11), pp.6314-21. ⟨10.4049/jimmunol.165.11.6314⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2000, 165 (11), pp.6314-21. ⟨10.4049/jimmunol.165.11.6314⟩
ResearcherID

CD8+ T cells are important effectors, as well as regulators, of organ-specific autoimmunity. Compared with Tc1-type CD8+ cells, Tc2 cells have impaired anti-viral and anti-tumor effector functions, although no data are yet available on their pathogen

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https://hal-pasteur.archives-ouvertes.fr/pasteur-01659367