Zobrazeno 1 - 10
of 15
pro vyhledávání: '"MESH: Deuterium Exchange Measurement"'
Autor:
Canul-Tec, Juan, Assal, Reda, Cirri, Erica, Legrand, Pierre, Brier, Sébastien, Chamot-Rooke, Julia, Reyes, Nicolas
Publikováno v:
Nature
Nature, Nature Publishing Group, 2017, 544 (7651), pp.446-451. ⟨10.1038/nature22064⟩
Nature, Nature Publishing Group, 2017, 544 (7651), pp.446-451. 〈10.1038/nature22064〉
Nature, 2017, 544 (7651), pp.446-451. ⟨10.1038/nature22064⟩
Nature, Nature Publishing Group, 2017, 544 (7651), pp.446-451. ⟨10.1038/nature22064⟩
Nature, Nature Publishing Group, 2017, 544 (7651), pp.446-451. 〈10.1038/nature22064〉
Nature, 2017, 544 (7651), pp.446-451. ⟨10.1038/nature22064⟩
International audience; Human members of the solute carrier 1 (SLC1) family of transporters take up excitatory neurotransmitters in the brain and amino acids in peripheral organs. Dysregulation of the function of SLC1 transporters is associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::35cff77c634037361ae6a5795e16f512
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/file/Canul-Tech-etal_nature_accepted_HAL.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/file/Canul-Tech-etal_nature_accepted_HAL.pdf
Autor:
O'Brien, Darragh, Brier, Sebastien, Ladant, Daniel, Durand, Dominique, Chenal, Alexandre, Vachette, Patrice
Publikováno v:
Biotechnology and Applied Biochemistry
Biotechnology and Applied Biochemistry, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
Biotechnology and Applied Biochemistry, Wiley, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
Biotechnology and Applied Biochemistry, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
Biotechnology and Applied Biochemistry, Wiley, 2018, 65 (1), pp.62-68. ⟨10.1002/bab.1577⟩
International audience; Small-angle X-ray scattering (SAXS) is a relatively simple experimental technique that provides information on the global conformation of macromolecules in solution, be they fully structured, partially, or extensively unfolded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::96c33eda3bfff7d7fcf6fc2e450384e0
https://hal.science/hal-02329435
https://hal.science/hal-02329435
Publikováno v:
Analytical Chemistry
Analytical Chemistry, American Chemical Society, 2015, 87 (13), pp.6681-6687. ⟨10.1021/acs.analchem.5b00831⟩
Analytical Chemistry, American Chemical Society, 2015, 87 (13), pp.6681-6687. ⟨10.1021/acs.analchem.5b00831⟩
International audience; The pitcher secretions of the Nepenthes genus of carnivorous plants contain a proteolytic activity that is very useful for hydrogen/deuterium exchange mass spectrometry (HX-MS). Our efforts to reconstitute pitcher fluid activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d63717ce1160541b46dd1233ddc6bd
https://doi.org/10.1021/acs.analchem.5b00831
https://doi.org/10.1021/acs.analchem.5b00831
Autor:
Bosmat Refaeli, Petr Man, Liat van Dijk, Moshe Giladi, Eric Forest, Daniel Khananshvili, Lior Almagor, Reuben Hiller
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (29), pp.12311-12323. ⟨10.1074/jbc.M117.787168⟩
Journal of Biological Chemistry, 2017, 292 (29), pp.12311-12323. ⟨10.1074/jbc.M117.787168⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2017, 292 (29), pp.12311-12323. ⟨10.1074/jbc.M117.787168⟩
Journal of Biological Chemistry, 2017, 292 (29), pp.12311-12323. ⟨10.1074/jbc.M117.787168⟩
International audience; Na(+)/Ca(2+) exchanger (NCX) proteins operate through the alternating access mechanism, where the ion-binding pocket is exposed in succession either to the extracellular or the intracellular face of the membrane. The archaeal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db149f8e673c6fd57bdf26a6166aeece
https://hal.archives-ouvertes.fr/hal-01647025
https://hal.archives-ouvertes.fr/hal-01647025
Publikováno v:
Analytica Chimica Acta
Analytica Chimica Acta, Elsevier Masson, 2012, 721, pp.7-21. ⟨10.1016/j.aca.2012.01.037⟩
Analytica Chimica Acta, Elsevier Masson, 2012, 721, pp.7-21. ⟨10.1016/j.aca.2012.01.037⟩
International audience; Assessing the functional outcome of protein interactions in structural terms is a goal of structural biology, however most techniques have a limited capacity for making structure-function determinations with both high resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f56dbcdb75593113ebaf2373ebd917a
https://doi.org/10.1016/j.aca.2012.01.037
https://doi.org/10.1016/j.aca.2012.01.037
Autor:
Thorsten Daubenfeld, Anne-Pascale Bouin, Human Rezaei, Jeanne Grosclaude, Yann Quenet, Guillaume van der Rest, Frederic Eghiaian, Marieke Van Audenhaege
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 18 (104), 7414-9. (2007)
Proceedings of the National Academy of Sciences of the United States of America 18 (104), 7414-7419. (2007)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104 (18), pp.7414-9. ⟨10.1073/pnas.0607745104⟩
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (18), pp.7414-9. ⟨10.1073/pnas.0607745104⟩
Proceedings of the National Academy of Sciences of the United States of America 18 (104), 7414-7419. (2007)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2007, 104 (18), pp.7414-9. ⟨10.1073/pnas.0607745104⟩
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (18), pp.7414-9. ⟨10.1073/pnas.0607745104⟩
The prion protein (PrP) propensity to adopt different structures is a clue to its biological role. PrP oligomers have been previously reported to bear prion infectivity or toxicity and were also found along the pathway of in vitro amyloid formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae07f5803ec6779f7a81f4137731ca8c
https://doi.org/10.1073/pnas.0607745104
https://doi.org/10.1073/pnas.0607745104
Autor:
Sven J. Saupe, Marie-Lise Maddelein, Christiane Ritter, Roland Riek, Ansgar B. Siemer, Matthias Ernst, Thorsten Lührs, Beat H. Meier
Publikováno v:
Nature
Nature, Nature Publishing Group, 2005, 435 (7043), pp.844-848. ⟨10.1038/nature03793⟩
Nature, Nature Publishing Group, 2005, 435 (7043), pp.844-848. ⟨10.1038/nature03793⟩
International audience; Prions are believed to be infectious, self-propagating polymers of otherwise soluble, host-encoded proteins. This concept is now strongly supported by the recent findings that amyloid fibrils of recombinant prion proteins from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c444eca8bc26615e394bcda7be412e
https://doi.org/10.1038/nature03793
https://doi.org/10.1038/nature03793
Publikováno v:
Topics in current chemistry
Topics in current chemistry, Springer, 2013, 331, pp.1-36
Topics in Current Chemistry ISBN: 9783642356643
Topics in current chemistry, 2013, 331, pp.1-36
Topics in current chemistry, Springer, 2013, 331, pp.1-36
Topics in Current Chemistry ISBN: 9783642356643
Topics in current chemistry, 2013, 331, pp.1-36
International audience; Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has been demonstrated to be a valuable tool to investigate noncovalent interactions of biomolecules. The direct detection of noncovalent assemblies is of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490dffb7cbeab37d48fdf3f666729c47
https://hal.univ-grenoble-alpes.fr/hal-01322386
https://hal.univ-grenoble-alpes.fr/hal-01322386
Publikováno v:
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2013, 12 (2), pp.539-548. ⟨10.1074/mcp.M112.023770⟩
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2013, 12 (2), pp.539-548. ⟨10.1074/mcp.M112.023770⟩
International audience; Hydrogen-deuterium exchange mass spectrometry is an important method for protein structure-function analysis. The bottom-up approach uses protein digestion to localize deuteration to higher resolution, and the essential measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3330154b9c262153c991f9245fff863c
https://europepmc.org/articles/PMC3567872/
https://europepmc.org/articles/PMC3567872/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (27), pp.10832-6. ⟨10.1073/pnas.1204067109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (27), pp.10832-6. ⟨10.1073/pnas.1204067109⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (27), pp.10832-6. ⟨10.1073/pnas.1204067109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (27), pp.10832-6. ⟨10.1073/pnas.1204067109⟩
International audience; The study of membrane proteins remains a challenging task, and approaches to unravel their dynamics are scarce. Here, we applied hydrogen/deuterium exchange (HDX) coupled to mass spectrometry to probe the motions of a bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103c1c6a8d57a9692ea2c229709c85a4
https://hal.archives-ouvertes.fr/hal-01004601/document
https://hal.archives-ouvertes.fr/hal-01004601/document