Zobrazeno 1 - 10
of 223
pro vyhledávání: '"MESH: DNA Damage"'
Autor:
Anna Seck, Salvatore De Bonis, Meike Stelter, Mats Ökvist, Müge Senarisoy, Mohammad Rida Hayek, Aline Le Roy, Lydie Martin, Christine Saint-Pierre, Célia M Silveira, Didier Gasparutto, Smilja Todorovic, Jean-Luc Ravanat, Joanna Timmins
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2023, 51 (6), pp.2931-2949. ⟨10.1093/nar/gkad108⟩
Nucleic Acids Research, 2023, 51 (6), pp.2931-2949. ⟨10.1093/nar/gkad108⟩
Bacterial nucleotide excision repair (NER), mediated by the UvrA, UvrB and UvrC proteins is a multistep, ATP-dependent process, that is responsible for the removal of a very wide range of chemically and structurally diverse DNA lesions. DNA damage re
Autor:
Fabienne Gauffre, Benjamin-Christoph Krause, Kevin Hogeveen, Caroline Fontana, Andreas Luch, Soizic Chevance, Sylvie Huet, Pégah Jalili, Yves Guichard, Agnès Burel, Valérie Fessard, Alfonso Lampen, Peter Laux
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2021, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, 2022, 78, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, Elsevier, 2021, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Toxicology in Vitro, 2022, 78, pp.105257. ⟨10.1016/j.tiv.2021.105257⟩
Background: Exposure of consumers to aluminum-containing nanomaterials (Al NMs) through numerous products is an area of concern for public health agencies since human health risks are not completely elucidated. In addition, the available data on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0779080d9b4b54625c6286ea013c059
https://hal.archives-ouvertes.fr/hal-03414646
https://hal.archives-ouvertes.fr/hal-03414646
Autor:
Lucy Kundura, Sandrine Gimenez, Renaud Cezar, Sonia André, Mehwish Younas, Yea-Lih Lin, Pierre Portalès, Claire Lozano, Charlotte Boulle, Jacques Reynes, Thierry Vincent, Clément Mettling, Philippe Pasero, Laurent Muller, Jean-Yves Lefrant, Claire Roger, Pierre-Géraud Claret, Sandra Duvnjak, Paul Loubet, Albert Sotto, Tu-Anh Tran, Jérôme Estaquier, Pierre Corbeau
Publikováno v:
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2022, 150 (3), pp.594-603.e2. ⟨10.1016/j.jaci.2022.06.020⟩
Journal of Allergy and Clinical Immunology, 2022, 150 (3), pp.594-603.e2. ⟨10.1016/j.jaci.2022.06.020⟩
International audience; Background: Lymphopenia is predictive of survival in patients with coronavirus disease 2019 (COVID-19).Objective: The aim of this study was to understand the cause of the lymphocyte count drop in severe forms of severe acute r
Autor:
Anna Seck, Salvatore De Bonis, Christine Saint-Pierre, Didier Gasparutto, Jean-Luc Ravanat, Joanna Timmins
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Communications Biology
Communications Biology, 2022, 5 (1), pp.127. ⟨10.1038/s42003-022-03064-x⟩
Communications Biology
Communications Biology, 2022, 5 (1), pp.127. ⟨10.1038/s42003-022-03064-x⟩
Nucleotide excision repair (NER) is a universal and versatile DNA repair pathway, capable of removing a very wide range of lesions, including UV-induced pyrimidine dimers and bulky adducts. In bacteria, NER involves the sequential action of the UvrA,
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9226, p 9226 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International audience; Cancer is the second leading cause of death with tens of millions of people diagnosed with cancer every year around the world. Most radio- and chemotherapies aim to eliminate cancer cells, notably by causing severe damage to t
Autor:
Paola Villani, Patrizia Eleuteri, Francesca Pacchierotti, Francesca Maranghi, Roberta Tassinari, Laura Narciso, Sabrina Tait, Gabriele Lori, Cristina Andreoli, Sylvie Huet, Gérard Jarry, Valérie Fessard, Eugenia Cordelli
Publikováno v:
Mutation Research-Genetic Toxicology and Environmental Mutagenesis
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 2022, 876-877, pp.503458. ⟨10.1016/j.mrgentox.2022.503458⟩
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 2022, 876-877, pp.503458. ⟨10.1016/j.mrgentox.2022.503458⟩
International audience; The genotoxicity of nano-structured synthetic amorphous silica (SAS), a common food additive, was investigated in vivo in rats. A 90-day oral toxicity study was performed according to OECD test guideline 408 and the genotoxici
Autor:
Bertrand H. Rihn, Zahra Doumandji, Jaafar Ghanbaja, Olivier Joubert, Reuben Mercier, Hilary Cassidy, Luc Ferrari, Mélanie M Leroux, David Matallanas, Sara Nahle
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, BioMed Central, 2020, 18 (1), pp.36. ⟨10.1186/s12951-020-0587-7⟩
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-18 (2020)
Journal of Nanobiotechnology, BioMed Central, 2020, 18 (1), pp.36. ⟨10.1186/s12951-020-0587-7⟩
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-18 (2020)
Functionalized multi-walled carbon nanotubes (MWCNT) have become the focus of increased research interest, particularly in their application as tools in different areas, such as the biomedical field. Despite the benefits associated with functionaliza
Autor:
Ian D. Waddell, Robert W. Sobol, Kate M. Smith, Justin L. Roncaioli, Felipe da Veiga Leprevost, Song My Hoang, Dattatreya Mellacharevu, Dominique Ray-Gallet, Michelle L. Lynskey, Roderick J. O’Sullivan, Ragini Bhargava, Jonathan Barroso-González, Nicole Kaminski, Geneviève Almouzni, Anne R. Wondisford, Jianfeng Li, Donald J. Ogilvie, Alexey I. Nesvizhskii, Dominic I. James, Callen T. Wallace, Simon C. Watkins, Laura García-Expósito
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
International audience; The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by poly(ADP-ribose) glycohydrolase (PARG) is essential for progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d45f0c33f255ca7323659e74359498
https://hal.sorbonne-universite.fr/hal-03138406
https://hal.sorbonne-universite.fr/hal-03138406
Autor:
Donato Angelino, Daniela Martini, Letizia Gigliotti, Marisa Porrini, Federico Ferreres, Thierry Durand, Alexandre Guy, Daniele Del Rio, Riccardo C. Bonadonna, Furio Brighenti, Monica Antonini, Michele Tassotti, Alessandra Dei Cas, Raúl Domínguez-Perles, Patrizia Riso, Mirko Marino, Alice Rosi, Sonia Medina, Hans Gottfried-Genieser, Cristian Ricci, Angel Gil-Izquierdo, Francesca Scazzina, Pedro Mena, Cristian Del Bo, Camille Oger
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nutrients
Nutrients, MDPI, 2021, 13 (7), pp.2399. ⟨10.3390/nu13072399⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 13
Issue 7
Nutrients, Vol 13, Iss 2399, p 2399 (2021)
Consejo Superior de Investigaciones Científicas (CSIC)
Nutrients
Nutrients, MDPI, 2021, 13 (7), pp.2399. ⟨10.3390/nu13072399⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 13
Issue 7
Nutrients, Vol 13, Iss 2399, p 2399 (2021)
The effect of coffee and cocoa on oxidative damage to macromolecules has been investigated in several studies, often with controversial results. This study aimed to investigate the effect of one-month consumption of different doses of coffee or cocoa
Publikováno v:
Mutation Research-Genetic Toxicology and Environmental Mutagenesis
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, Elsevier, 2020, 850, 5 p. ⟨10.1016/j.mrgentox.2020.503161⟩
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, Elsevier, 2020, 850, 5 p. ⟨10.1016/j.mrgentox.2020.503161⟩
Through diet, people are chronically exposed to low doses of a large number of contaminants that could exhibit adverse health effects. Toxicological evaluation of food contaminants increases in complexity when the exposure involves chemical mixtures.