Zobrazeno 1 - 10
of 49
pro vyhledávání: '"MESH: Cytidine"'
Autor:
Fran Robson, Palma Rocchi, Sinem Demirbag, Thi Khanh Le, Khadija Shahed Khan, Clément Paris, Peter Barfuss, Wai-Lung Ng
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, Elsevier, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Summary The coronavirus disease 2019 (COVID-19) that is wreaking havoc on global public health and economies has heightened awareness about the lack of effective antiviral treatments for human coronaviruses (CoVs). Many current antivirals, notably nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7c3d34b3a0e2ab6d0db7eece5c7f1
https://pubmed.ncbi.nlm.nih.gov/33338403
https://pubmed.ncbi.nlm.nih.gov/33338403
Publikováno v:
British Journal of Clinical Pharmacology, 85(6), 1213-1214. Wiley-Blackwell
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Br J Clin Pharmacol
British Journal of Clinical Pharmacology, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Peters, G J, Giovannetti, E, Honeywell, R J & Ciccolini, J 2019, ' Can cytidine deaminase be used as predictive biomarker for gemcitabine toxicity and response? ', British Journal of Clinical Pharmacology, vol. 85, no. 6, pp. 1213-1214 . https://doi.org/10.1111/bcp.13921
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Br J Clin Pharmacol
British Journal of Clinical Pharmacology, 2019, 85 (6), pp.1213-1214. ⟨10.1111/bcp.13921⟩
Peters, G J, Giovannetti, E, Honeywell, R J & Ciccolini, J 2019, ' Can cytidine deaminase be used as predictive biomarker for gemcitabine toxicity and response? ', British Journal of Clinical Pharmacology, vol. 85, no. 6, pp. 1213-1214 . https://doi.org/10.1111/bcp.13921
AIMS: Cytidine deaminase (CDA) activity in cancer patients' serum has been proposed as a predictive biomarker for efficacy and toxicity of nucleoside analogues. However, discrepant results about its predictive value have been reported due to the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a658b4312f797092c0ff06a6dd72ea30
https://research.vumc.nl/en/publications/0a51241b-8ca4-4447-8880-7e7e7bccc9c8
https://research.vumc.nl/en/publications/0a51241b-8ca4-4447-8880-7e7e7bccc9c8
Autor:
Caval, Mohamed S. Bouzidi, Jean-Pierre Vartanian, Michel Henry, Rodolphe Suspène, Simon Wain-Hobson
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 2014, 110 (10), pp.2615-2622. ⟨10.1038/bjc.2014.176⟩
British Journal of Cancer, 2014, 110 (10), pp.2615-2622. ⟨10.1038/bjc.2014.176⟩
International audience; Background: The revolution in cancer genomics shows that the dominant mutations are CG->TA transitions. The sources of these mutations are probably two host cell cytidine deaminases APOBEC3A and APOBEC3B. The former in particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfee682b49b4e289cb39e5876039f22
http://europepmc.org/articles/PMC4021520
http://europepmc.org/articles/PMC4021520
Publikováno v:
Molecular Biology and Evolution
Molecular Biology and Evolution, 2014, 31 (2), pp.330-340. ⟨10.1093/molbev/mst195⟩
Molecular Biology and Evolution, 2014, 31 (2), pp.330-340. ⟨10.1093/molbev/mst195⟩
International audience; The human APOBEC3 gene cluster locus encodes polynucleotide cytidine deaminases. Although many act as viral restriction factors through mutation of single-stranded DNA, recent reports have shown that human APOBEC3A was capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47840f223a21ab569487e3e51ecd161
https://doi.org/10.1093/molbev/mst195
https://doi.org/10.1093/molbev/mst195
Autor:
Vincent Caval, J Thalmensi, T Bestetti, E Pliquet, L Fiette, M Julithe, T. Huet, Anna Kostrzak, M Escande, Simon Wain-Hobson, Pierre Langlade-Demoyen
Publikováno v:
Gene Therapy
Gene Therapy, Nature Publishing Group, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩
Gene Therapy, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩
Gene Therapy, Nature Publishing Group, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩
Gene Therapy, 2017, 24 (2), pp.74-83. ⟨10.1038/gt.2016.77⟩
International audience; Human APOBEC3A (A3A) cytidine deaminase shows pro-apoptotic properties resulting from hypermutation of genomic DNA, induction of double-stranded DNA breaks (DSBs) and G1 cell cycle arrest. Given this, we evaluated the antitumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8487b68fc1c4afe01c1197b742d10a6
https://hal-pasteur.archives-ouvertes.fr/pasteur-02545771
https://hal-pasteur.archives-ouvertes.fr/pasteur-02545771
Autor:
Denise Guetard, Marc Sitbon, Jean-Pierre Vartanian, Anne Keriel, Myrtille Renard, Simon Wain-Hobson, Vincent Petit
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. 〈10.1016/j.jmb.2008.10.043〉
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, 2009, 385 (1), pp.65-78. ⟨10.1016/j.jmb.2008.10.043⟩
Journal of Molecular Biology, Elsevier, 2009, 385 (1), pp.65-78. 〈10.1016/j.jmb.2008.10.043〉
International audience; Mammalian APOBEC molecules comprise a large family of cytidine deaminases with specificity for RNA and single-stranded DNA (ssDNA). APOBEC1s are invariably highly specific and edit a single residue in a cellular mRNA, while th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f626191735899316af06474026ef258
https://doi.org/10.1016/j.jmb.2008.10.043
https://doi.org/10.1016/j.jmb.2008.10.043
Autor:
Samuel Aparicio, Jessica Zucman-Rossi, Julia Richter, Stefan M. Pfister, Matthias Schlesner, Nikhil C. Munshi, Sean M. Grimmond, Andrew V. Biankin, Christine Desmedt, Rafael Valdés-Mas, Ton N. Schumacher, Elias Campo, Marina Pajic, Peter J. Campbell, Lucy R. Yates, David T. W. Jones, Laura van ’t Veer, Michael R. Stratton, Carlos Caldas, Matthew Meyerson, Hiromi Nakamura, Sandrine Boyault, Anne Vincent-Salomon, Keiran Raine, Peter Lichter, Marit M. van Buuren, Tomislav Ilicic, Stian Knappskog, Ultan McDermott, Sancha Martin, Andrew Tutt, Icgc PedBrain, Helen Davies, Barbara Hutter, Philip Rosenstiel, Sunil R. Lakhani, Marcin Imielinsk, John A. Foekens, Fumie Hosoda, Sandrine Imbeaud, Elli Papaemmanuil, David T. Jones, Nicola Waddell, Serena Nik-Zainal, Marcel Kool, Graham R. Bignell, Yasushi Totoki, Manasa Ramakrishna, Paul A. Northcott, Niccolo Bolli, Xose S. Puente, Adam Butler, Åke Borg, David C. Wedge, Jon W. Teague, Andrea L. Richardson, Reiner Siebert, Tatsuhiro Shibata, John V. Pearson, Carlos López-Otín, Angelo Paradiso, P. Andrew Futreal, Anne Lise Børresen-Dale, Sam Behjati, Birgit Burkhardt, Paul N. Span, Jorunn E. Eyfjord, Mel Greaves, Roland Eils, Ludmil B. Alexandrov, Natalie Jäger
Publikováno v:
Nature, 500(7463), 415-421. Nature Publishing Group
Nature, 500, 7463, pp. 415-21
Nature, 500(7463), 415-+. Nature Publishing Group
Nature
Nature, Nature Publishing Group, 2013, 500 (7463), pp.415-421. ⟨10.1038/nature12477⟩
Nature, 500, 415-21
Nature, 500, 7463, pp. 415-21
Nature, 500(7463), 415-+. Nature Publishing Group
Nature
Nature, Nature Publishing Group, 2013, 500 (7463), pp.415-421. ⟨10.1038/nature12477⟩
Nature, 500, 415-21
Item does not contain fulltext All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a cancer genome bears the signatures of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fee3e415d4bed41eac85c28a1541a0
https://doi.org/10.1038/nature12477
https://doi.org/10.1038/nature12477
Autor:
Alexis Saintamand, Yves Denizot, Michel Cogné, Christelle Vincent-Fabert, Bernardo Reina-San-Martin, Pauline Rouaud, Isabelle Robert, Rémi Fiancette, Eric Pinaud, Marie Marquet
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Somatic hypermutation in variable heavy chain rearranged regions is abrogated in the absence of the 3′ regulatory region enhancer, whereas transcription rate in the Ig heavy chain is only partially reduced.
Interactions with cognate antigens r
Interactions with cognate antigens r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80c73517706ccf8515835fcf135780f
https://doi.org/10.1084/jem.20130072
https://doi.org/10.1084/jem.20130072
Autor:
Pierre Briozzo, Thomas Bertrand, Augustin Ofiteru, Béatrice Golinelli-Pimpaneau, Nadia Bucurenci, Anne-Marie Gilles, Octavian Bârzu, Liliane Assairi, Hélène Munier-Lehmann
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
Journal of Molecular Biology, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
Journal of Molecular Biology, Elsevier, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
Journal of Molecular Biology, 2002, 315 (5), pp.1099-110. ⟨10.1006/jmbi.2001.5286⟩
International audience; Bacterial cytidine monophosphate (CMP) kinases are characterised by an insert enlarging their CMP binding domain, and by their particular substrate specificity. Thus, both CMP and 2'-deoxy-CMP (dCMP) are good phosphate accepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ac4d444cbef836fb829e8bc3e8aa96
https://doi.org/10.1006/jmbi.2001.5286
https://doi.org/10.1006/jmbi.2001.5286
Autor:
Benoit Arcangioli, Hanen Ouadani, Beya Larguèche, Imen Ben-Mustapha, Hatem Masmoudi, François Rougeon, Houda Elloumi-Zghal, Mohamed-Ridha Barbouche, Tihana Jovanic, Meriem Ben-Ali, Mongia Hachicha, Dahmani M. Fathallah, Sylvie Garcia
Publikováno v:
Molecular Immunology
Molecular Immunology, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩
Molecular Immunology, Elsevier, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩
Molecular Immunology, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩
Molecular Immunology, Elsevier, 2016, 79, pp.77-82. ⟨10.1016/j.molimm.2016.09.025⟩
International audience; Activation induced cytidine deaminase (AID) is an essential enzyme for class switch recombination (CSR) and somatic hypermutation (SHM) during secondary immune response. Mutations in the AICDA gene are responsible for Hyper Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d198ff026ab2745225baea1a94295f
https://hal-riip.archives-ouvertes.fr/pasteur-01453058
https://hal-riip.archives-ouvertes.fr/pasteur-01453058