Výsledky vyhledávání - "MESH: Cycloheximide"

Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex

Autor: T. Dumontet, Antoine Martinez, Bruno Ragazzon, Anne-Marie Lefrançois-Martinez, Jean-Christophe Pointud, Nathanaëlle Montanier, Jérôme Bertherat, Igor Tauveron, Florence Roucher-Boulez, Isabelle Sahut-Barnola, Annabel Berthon, Damien Dufour, Pierre Val, Cyril Djari, M. Batisse-Lignier

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2019, 33 (9), pp.10218-10230. ⟨10.1096/fj.201900557R⟩
FASEB Journal, 2019, 33 (9), pp.10218-10230. ⟨10.1096/fj.201900557R⟩

SUMOylation is a highly conserved and dynamic post-translational mechanism primarily affecting nuclear programs for adapting organisms to stressful challenges. Alteration of SUMOylation cycles leads to severe developmental and homeostatic defects and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4d363279b1383215c0440c4736dec9
https://hal.archives-ouvertes.fr/hal-02351273

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Type I interferon-enhanced IL-10 expression in human CD4 T cells is regulated by STAT3, STAT2, and BATF transcription factors

Autor: Umeshree Govender, Frédérique Michel, Yasmine Bourdache, Sandra Pellegrini, Béatrice Corre

Publikováno v: Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, 2017, 101 (5), pp.1181-1190. ⟨10.1189/jlb.2A0416-187RR⟩
Journal of Leukocyte Biology, 2017, 101 (5), pp.1181-1190. ⟨10.1189/jlb.2A0416-187RR⟩

Type I IFN can exert pro- and anti-inflammatory activities in the immune system. Here, we have investigated the mechanism by which IFN-α enhances early expression of the anti-inflammatory cytokine IL-10 in human CD45RA+CD4+ T cells. With the use of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2464e50cc98856b4358c2ff846e243
https://hal-pasteur.archives-ouvertes.fr/pasteur-02136992

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p53 Activation by Nitric Oxide Involves Down-regulation of Mdm2

Autor: Gilbert de Murcia, Xinjiang Wang, Dan Michael, Moshe Oren

Publikováno v: J Biol Chem
J Biol Chem, 2002, 277 (18), pp.15697-702. ⟨10.1074/jbc.M112068200⟩

Nitric oxide (NO) is an important bioactive molecule involved in a variety of physiological and pathological processes. At the same time, NO is also an inducer of stress signaling, owing to its ability to damage proteins and DNA. NO was reported to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cde471a1df6bad50b1f2cfd4d3e03d
https://doi.org/10.1074/jbc.m112068200

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Zinc oxide nanoparticles delay human neutrophil apoptosis by a de novo protein synthesis-dependent and reactive oxygen species-independent mechanism

Autor: Goncalves, David M, Girard, D., Goncalves, David

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2014, 28 (5), pp.926-931. ⟨10.1016/j.tiv.2014.03.002⟩

International audience; Highlights ZnO nanoparticles are antiapoptotic for human neutrophils. ZnO nanoparticles do not increase ROS production in human neutrophils. ZnO nanoparticles induce de novo protein synthesis in human neutrophils. Abstract Inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc57eaf2d6942eda3c347721b7eaa1f9
https://hal.archives-ouvertes.fr/hal-01197015

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Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes

Autor: Dalila Azzout-Marniche, Marc Foretz, Fabienne Foufelle, Pascal Ferré, Colette Guichard, Dominique Bécard

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2000, pp.389-93
Biochemical Journal, Portland Press, 2000, 350 Pt 2, pp.389-93
Biochemical Journal, 2000, pp.389-93

International audience; The transcription factor sterol regulatory-element-binding protein-1c (SREBP-1c) plays a major role in the effect of insulin on the transcription of hepatic genes such as glucokinase and fatty acid synthase. We show here in cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effc863bd25fb88902a8fb2547e1d75c
https://hal-agroparistech.archives-ouvertes.fr/hal-01611459

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Synchronous protein cycling in batch cultures of the yeast Saccharomyces cerevisiae at log growth phase

Autor: Enrico Cundari, Michele M. Bianchi, Lorenzo Farina, Marco Crescenzi, Rodolfo Negri, Alessandro Giuliani, Gabriele Romagnoli

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2011, 317 (20), pp.2958-68. ⟨10.1016/j.yexcr.2011.09.007⟩
Experimental Cell Research, Elsevier, 2011, 317 (20), pp.2958-68. <10.1016/j.yexcr.2011.09.007>

International audience; The assumption that cells are temporally organized systems, i.e. showing relevant dynamics of their state variables such as gene expression or protein and metabolite concentration, while tacitly given for granted at the molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b71bb1bbfb682d4b2ebd07f0a2beb23
https://hal-riip.archives-ouvertes.fr/pasteur-00978685

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1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells

Autor: Xavier Tekpli, Kjetil Ask, Nana Asare, Nina E. Landvik, Jørn A. Holme, Marit Låg, Dominique Lagadic-Gossmann, Mary Rissel

Publikováno v: Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, 2008, 230 (2), pp.175-86. ⟨10.1016/j.taap.2008.02.015⟩
Toxicology and Applied Pharmacology, Elsevier, 2008, 230 (2), pp.175-86. ⟨10.1016/j.taap.2008.02.015⟩

International audience; Mechanistic studies of nitro-PAHs (polycyclic aromatic hydrocarbons) of interest might help elucidate which chemical characteristics are most important in eliciting toxic effects. 1-Nitropyrene (1-NP) is the predominant nitrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7286662adaeffbe8dc952deb6b580ba5
https://hal.science/hal-00674320

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The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation

Autor: Moustapha Cisse, Cristine Alves da Costa, Claire Sunyach, Frédéric Checler, Bruno Vincent

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (3), pp.1956-63. ⟨10.1074/jbc.M609663200⟩

The cellular prion protein (PrP(c)) undergoes various endopro-teolytic attacks within its N-terminal domain, leading to the production of C-terminal fragments (C) tethered to the plasma membrane and soluble N-terminal peptides (N). One of these cleav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1179246d7c5556c66828f1698ea17f1
https://hal.archives-ouvertes.fr/hal-00170815

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Knock-in mice reveal nonsense-mediated mRNA decay in the brain

Autor: Brigitte L. Kieffer, Candice Contet, Andrée Dierich

Publikováno v: Genesis
Genesis, Wiley-Blackwell, 2007, 45 (1), pp.38-43. ⟨10.1002/dvg.20263⟩

Nonsense-mediated mRNA decay (NMD) is a process of mRNA surveillance that degrades transcripts harboring a premature termination codon (PTC). Mammalian NMD was mostly studied in cultured cells so far and there was no direct evidence yet that NMD coul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76eccc1a93103967143c6b446c90aa26
https://hal.archives-ouvertes.fr/hal-00188251

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Regulation of Rho signaling pathways in interleukin-2-stimulated human T-lymphocytes

Autor: Caroline Liot, Christelle Thibault, Josiane Pierre, Gervaise Loirand, Jacques Bertoglio, Pierre Pacaud, Anick Auger, Laetitia Seguin, Rym Mzali

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2005, 19 (13), pp.1911-3. ⟨10.1096/fj.05-4030fje⟩

Rho GTPases are key regulators of many cellular functions, including cytoskeleton organization which is important for cell morphology and mobility, gene expression, cell cycle progression, and cytokinesis. In addition, it has recently been recognized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4d3d843fe8b4bd3957bdea4bf158f0
https://pubmed.ncbi.nlm.nih.gov/16148026

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