Zobrazeno 1 - 10
of 16
pro vyhledávání: '"MESH: Computational Biology/methods"'
Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission
Autor:
Aditi Alaganan, Chetan E. Chitnis, Lhousseine Touqui, Julien Guglielmini, Kunal R. More, Micheline Guillotte Blisnick, Sabine Thiberge, Shailja Singh, Audrey Lorthiois, Olivier Gorgette, Pallavi Singh, Shivani Shankar Aguilera
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (35), pp.17498-17508. ⟨10.1073/pnas.1900266116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (35), pp.17498-17508. ⟨10.1073/pnas.1900266116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (35), pp.17498-17508. ⟨10.1073/pnas.1900266116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (35), pp.17498-17508. ⟨10.1073/pnas.1900266116⟩
International audience; Transmission of Plasmodium falciparum involves a complex process that starts with the ingestion of gametocytes by female Anopheles mosquitoes during a blood meal. Activation of gametocytes in the mosquito midgut triggers "roun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcde94b87420e035dae4c10cfcf1d635
https://hal-pasteur.archives-ouvertes.fr/pasteur-02890967
https://hal-pasteur.archives-ouvertes.fr/pasteur-02890967
Autor:
Hatice Akarsu, Patricia Bordes, Moise Mansour, Donna-Joe Bigot, Pierre Genevaux, Laurent Falquet
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Public Library of Science, 2019, 15 (4), pp.e1006946. ⟨10.1371/journal.pcbi.1006946⟩
PLoS Computational Biology, Vol 15, Iss 4, p e1006946 (2019)
PLoS Computational Biology, Public Library of Science, 2019, 15 (4), pp.e1006946. ⟨10.1371/journal.pcbi.1006946⟩
PLoS Computational Biology, Vol 15, Iss 4, p e1006946 (2019)
Bacterial Toxin-Antitoxin systems (TAS) are involved in key biological functions including plasmid maintenance, defense against phages, persistence and virulence. They are found in nearly all phyla and classified into 6 different types based on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::94c638710663a53516fa191eeb0f73ff
https://hal.archives-ouvertes.fr/hal-02397097
https://hal.archives-ouvertes.fr/hal-02397097
Publikováno v:
Legionella: Methods and Protocols
Carmen Buchrieser; Hubert Hilbi. Legionella: Methods and Protocols, 1921 (27), Springer Science; Business Media, LLC, pp.429-443, 2019, Methods in Molecular Biology (MIMB), 978-1-4939-9047-4 (Print), 978-1-4939-9048-1 (Online). ⟨10.1007/978-1-4939-9048-1_27⟩
Methods in Molecular Biology ISBN: 9781493990474
Carmen Buchrieser; Hubert Hilbi. Legionella: Methods and Protocols, 1921 (27), Springer Science; Business Media, LLC, pp.429-443, 2019, Methods in Molecular Biology (MIMB), 978-1-4939-9047-4 (Print), 978-1-4939-9048-1 (Online). ⟨10.1007/978-1-4939-9048-1_27⟩
Methods in Molecular Biology ISBN: 9781493990474
International audience; The analysis of the lung microbiome composition is a field of research that recently emerged. It gained great interest in pulmonary diseases such as pneumonia since the microbiome seems to be involved in host immune responses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8451ab4b0ea477fc79f644f33611fcda
https://hal-pasteur.archives-ouvertes.fr/pasteur-02895180
https://hal-pasteur.archives-ouvertes.fr/pasteur-02895180
Autor:
Gordon Dougan, Ana Elena Pérez-Cobas, Christophe Rusniok, Sandra Reuter, Carmen Buchrieser, Jasmin Demirtas, Shivani Pasricha, Elizabeth L. Hartland, Gunnar N. Schroeder, Gad Frankel, S. Jarraud, Sonia Mondino, Laura Gomez-Valero, Johannes Crumbach, Monica Rolando, Stéphane Descorps-Declère, Danielle Carson
Publikováno v:
Gomez-Valero, L, Rusniok, C, Carson, D, Mondino, S, Pérez-Cobas, A E, Rolando, M, Pasricha, S, Reuter, S, Demirtas, J, Crumbach, J, Descorps-Declere, S, Hartland, E L, Jarraud, S, Dougan, G, Schroeder, G N, Frankel, G & Buchrieser, C 2019, ' More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.1808016116, https://doi.org/10.1101/350777
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2265-2273. ⟨10.1073/pnas.1808016116⟩
The genus Legionella comprises 65 species, among which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c453963aa5d05c45e4f3bbed371caec
https://pure.qub.ac.uk/en/publications/more-than-18000-effectors-in-the-legionella-genus-genome-provide-multiple-independent-combinations-for-replication-in-human-cells(8cb35736-8923-4ed6-920d-e29c42f7d390).html
https://pure.qub.ac.uk/en/publications/more-than-18000-effectors-in-the-legionella-genus-genome-provide-multiple-independent-combinations-for-replication-in-human-cells(8cb35736-8923-4ed6-920d-e29c42f7d390).html
Autor:
Sergouniotis, Panagiotis I., Maxime, Emmanuel, Leroux, Dorothée, Olry, Annie, Thompson, Rachel, Rath, Ana, Robinson, Peter N., Dollfus, Hélèneashworth, Jl, Audo, I, Balciuniene, Vj, Banin, E, Black, Gc, Böhringer, D, Boon, Cjf, Bremond-Gignac, D, Calvas, P, Castela, G, Dagnelie, G, Dollfus, H, Downes, Sm, Fasolo, A, Fasser, C, Gelzinis, A, Goetz, K, Hamann, S, Héon, E, Iarossi, G, Kawasaki, A, Keegan, D, Kessel, L, Khan, K, Klett, A, Köhler, S, Leroux, D, Leroy, Bp, Lisch, W, Liskova, P, Lorenz, B, Maggi, R, Maxime, E, Meunier, I, Mohand-Said, S, Nowomiejska, K, Perdomo, Y, Petzold, A, Preising, M, Robinson, Pn, Scholl, Hpn, Sergouniotis, Pi, Sodi, A, Stingl, K, Studer, F, Suppiej, A, Thompson, R, Touitou, V, Traboulsi, E, Trumpaitis, J, Tuft, Sj, Vaclavik, V, Valeina, S, Van Cauwenbergh, C, Verloes, A, Vighetto, A, Wheeler, R, Wheeler-Schilling, T, Yu-Wai-Man, P, Zobor, D, Zrenner, E.
Publikováno v:
ERN-EYE Ontology Study Group 2019, ' An ontological foundation for ocular phenotypes and rare eye diseases ', Orphanet Journal of Rare Diseases, vol. 14, no. 1, pp. 8 . https://doi.org/10.1186/s13023-018-0980-6
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, 14
Orphanet Journal of Rare Diseases, 2019, 14 (8), pp.1-5. ⟨10.1186/s13023-018-0980-6⟩
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-5 (2019)
Sergouniotis, P I, Maxime, E, Leroux, D, Olry, A, Thompson, R, Rath, A, Robinson, P N, Dollfus, H, ERN-EYE Ontology Study Group, Ashworth, J L, Audo, I, Balciuniene, V J, Hamann, S, Kessel, L, Yu-Wai-Man, P, Zobor, D & Zrenner, E 2019, ' An ontological foundation for ocular phenotypes and rare eye diseases ', Orphanet Journal of Rare Diseases, vol. 14, 8 . https://doi.org/10.1186/s13023-018-0980-6
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, 14
Orphanet Journal of Rare Diseases, 2019, 14 (8), pp.1-5. ⟨10.1186/s13023-018-0980-6⟩
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-5 (2019)
Sergouniotis, P I, Maxime, E, Leroux, D, Olry, A, Thompson, R, Rath, A, Robinson, P N, Dollfus, H, ERN-EYE Ontology Study Group, Ashworth, J L, Audo, I, Balciuniene, V J, Hamann, S, Kessel, L, Yu-Wai-Man, P, Zobor, D & Zrenner, E 2019, ' An ontological foundation for ocular phenotypes and rare eye diseases ', Orphanet Journal of Rare Diseases, vol. 14, 8 . https://doi.org/10.1186/s13023-018-0980-6
Background The optical accessibility of the eye and technological advances in ophthalmic diagnostics have put ophthalmology at the forefront of data-driven medicine. The focus of this study is rare eye disorders, a group of conditions whose clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840fa6905fa94a0e7ca88a0762068559
https://doi.org/10.1186/s13023-018-0980-6
https://doi.org/10.1186/s13023-018-0980-6
Autor:
Sumir Panji, Julie Makani, Liberata Mwita, Cherif Ben Hamda, Kais Ghedira, Raphael Z. Sangeda, Alia Benkahla, Ayton Meintjes, Lamia Guizani-Tabbane, Siana Nkya, Nicola Mulder
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (7), pp.e0199461. ⟨10.1371/journal.pone.0199461⟩
PLoS ONE, Vol 13, Iss 7, p e0199461 (2018)
PLoS ONE, Public Library of Science, 2018, 13 (7), pp.e0199461. ⟨10.1371/journal.pone.0199461⟩
PLoS ONE, Vol 13, Iss 7, p e0199461 (2018)
International audience; A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysi-ology. Nonetheless, the principal dysregulated factors affecting this major pathway and their mechanisms of action still have to be f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9c4bed394da9f0ff5a67ac94d7f98a
http://europepmc.org/articles/PMC6034806
http://europepmc.org/articles/PMC6034806
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, 2017, 13 (8), pp.e1005666. ⟨10.1371/journal.pcbi.1005666⟩
PLoS Computational Biology, Vol 13, Iss 8, p e1005666 (2017)
PLoS Computational Biology, Public Library of Science, 2017, 13 (8), pp.e1005666. ⟨10.1371/journal.pcbi.1005666⟩
PLoS Computational Biology, 2017, 13 (8), pp.e1005666. ⟨10.1371/journal.pcbi.1005666⟩
PLoS Computational Biology, Vol 13, Iss 8, p e1005666 (2017)
PLoS Computational Biology, Public Library of Science, 2017, 13 (8), pp.e1005666. ⟨10.1371/journal.pcbi.1005666⟩
Hospital-acquired infections (HAIs), including emerging multi-drug resistant organisms, threaten healthcare systems worldwide. Efficient containment measures of HAIs must mobilize the entire healthcare network. Thus, to best understand how to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b99fec425fca52455ad91eeee4c7538
https://hal.science/hal-01578692
https://hal.science/hal-01578692
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep35065⟩
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep35065⟩
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep35065⟩
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep35065⟩
UV irradiation is a major environmental factor causing skin dryness, aging and cancer. UVB in particular triggers cumulative DNA damage, oxidative stress and mitochondrial dysfunction. The objective of our study was to provide both qualitative and qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf15385655ef23cec98f71cab15cff6
Autor:
François Moutou, Meriadeg Ar Gouilh, Laure Diancourt, Fabien Miszczak, Valérie Caro, Astrid Vabret, Nathalie Kin
Publikováno v:
Infection, Genetics and Evolution
Infection, Genetics and Evolution, Elsevier, 2016, 40, pp.186-191. ⟨10.1016/j.meegid.2016.03.006⟩
Infection, Genetics and Evolution, 2016, 40, pp.186-191. ⟨10.1016/j.meegid.2016.03.006⟩
Infection, Genetics and Evolution, Elsevier, 2016, 40, pp.186-191. ⟨10.1016/j.meegid.2016.03.006⟩
Infection, Genetics and Evolution, 2016, 40, pp.186-191. ⟨10.1016/j.meegid.2016.03.006⟩
Bovine coronaviruses (BCoVs) are widespread around the world and cause enteric or respiratory infections among cattle. The current study includes 13 samples from BCoVs collected in Normandy during an 11-year period (from 2003 to 2014), 16 French HCoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7b45d683535497f60d6f83d3b52791
https://hal-normandie-univ.archives-ouvertes.fr/hal-02367384
https://hal-normandie-univ.archives-ouvertes.fr/hal-02367384
Autor:
Hua Wong, Pascal Carrivain, Emmanuelle Fabre, Hervé Blanc, Sébastien Herbert, Christophe Zimmer, Romain Koszul, Hervé Marie-Nelly
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2012, 22 (20), pp.1881-1890. ⟨10.1016/j.cub.2012.07.069⟩
Current Biology-CB, 2012, 22 (20), pp.1881-1890. ⟨10.1016/j.cub.2012.07.069⟩
Current Biology-CB, Elsevier, 2012, 22 (20), pp.1881-1890. ⟨10.1016/j.cub.2012.07.069⟩
Current Biology-CB, 2012, 22 (20), pp.1881-1890. ⟨10.1016/j.cub.2012.07.069⟩
International audience; BackgroundDespite the absence of internal membranes, the nucleus of eukaryotic cells is spatially organized, with chromosomes and individual loci occupying dynamic, but nonrandom, spatial positions relative to nuclear landmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0290bf1e3cb321ae59660467375855