Zobrazeno 1 - 10
of 15
pro vyhledávání: '"MESH: Clustered Regularly Interspaced Short Palindromic Repeats"'
Autor:
Jean-Philippe Vernadet, Christine Pourcel, David Couvin, Marie Touchon, Gilles Vergnaud, Nicolas Villeriot, Claire Toffano-Nioche
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (D1), pp.D535-D544. ⟨10.1093/nar/gkz915⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (D1), pp.D535-D544. ⟨10.1093/nar/gkz915⟩
Nucleic Acids Research, Oxford University Press, 2019, ⟨10.1093/nar/gkz915⟩
Nucleic Acids Research, 2020, 48 (D1), pp.D535-D544. ⟨10.1093/nar/gkz915⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (D1), pp.D535-D544. ⟨10.1093/nar/gkz915⟩
Nucleic Acids Research, Oxford University Press, 2019, ⟨10.1093/nar/gkz915⟩
In Archaea and Bacteria, the arrays called CRISPRs for ‘clustered regularly interspaced short palindromic repeats’ and the CRISPR associated genes or cas provide adaptive immunity against viruses, plasmids and transposable elements. Short sequenc
Autor:
Lazar Ranin, Philippe Glaser, Claire Poyart, Ina Gajic, Céline Plainvert, Asmaa Tazi, Dusan Kekic, Nicolas Dmytruk, Vera Mijac, Natasa Opavski
Publikováno v:
International Journal of Medical Microbiology
International Journal of Medical Microbiology, Elsevier, 2019, 309 (1), pp.19-25. ⟨10.1016/j.ijmm.2018.10.005⟩
International Journal of Medical Microbiology, 2019, 309 (1), pp.19-25. ⟨10.1016/j.ijmm.2018.10.005⟩
International Journal of Medical Microbiology, Elsevier, 2019, 309 (1), pp.19-25. ⟨10.1016/j.ijmm.2018.10.005⟩
International Journal of Medical Microbiology, 2019, 309 (1), pp.19-25. ⟨10.1016/j.ijmm.2018.10.005⟩
International audience; Streptococcus agalactiae (group B Streptococcus, GBS) remains the leading cause of invasive diseases in neonates and an important cause of infections in the elderly. The aim of this study was to access the prevalence of GBS ge
Autor:
Lucy Glover
Publikováno v:
MSphere
MSphere, American Society for Microbiology., 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere
mSphere, Vol 5, Iss 1, p e00001-20 (2020)
MSphere, 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere, Vol 5, Iss 1 (2020)
MSphere, American Society for Microbiology., 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere
mSphere, Vol 5, Iss 1, p e00001-20 (2020)
MSphere, 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere, Vol 5, Iss 1 (2020)
Lucy Glover’s research focuses on the role of DNA repair and recombination in antigenic variation in the parasite Trypanosoma brucei, the causative agent of both human and animal African trypanosomiasis. In this mSphere of Influence article, she re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fbc5aa136cb2a51fa80e59786e39ea
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107138/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107138/document
Autor:
Mart Krupovic, Eugene V. Koonin
Publikováno v:
Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2020, 5 (1), pp.8-9. ⟨10.1038/s41564-019-0635-y⟩
Nature Microbiology, 2020, 5 (1), pp.8-9. ⟨10.1038/s41564-019-0635-y⟩
Nature Microbiology, Nature Publishing Group, 2020, 5 (1), pp.8-9. ⟨10.1038/s41564-019-0635-y⟩
Nature Microbiology, 2020, 5 (1), pp.8-9. ⟨10.1038/s41564-019-0635-y⟩
Comment on : A jumbo phage that forms a nucleus-like structure evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity. [Nat Microbiol. 2020]; International audience; Two recent studies reveal a virus anti-defence strategy wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6bb75a018995730037b161e525e11f
https://hal-pasteur.archives-ouvertes.fr/pasteur-02559911
https://hal-pasteur.archives-ouvertes.fr/pasteur-02559911
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2018, 200, pp.e00580-17. ⟨10.1128/JB.00580-17⟩
Journal of Bacteriology, 2018, 200, pp.e00580-17. ⟨10.1128/JB.00580-17⟩
Journal of Bacteriology, American Society for Microbiology, 2018, 200, pp.e00580-17. ⟨10.1128/JB.00580-17⟩
Journal of Bacteriology, 2018, 200, pp.e00580-17. ⟨10.1128/JB.00580-17⟩
Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are well-known acquired immunity systems that are widespread in archaea and bacteria. The RNA-guided nucleases from CRISPR-Cas systems are currently regarded as the most re
Autor:
Catherine L. Weiner, Poulami Samai, Luciano A. Marraffini, Gregory W. Goldberg, Robert Heler, Joshua W. Modell, David Bikard
Publikováno v:
Nature
Nature, 2015, 519 (7542), pp.199-202. ⟨10.1038/nature14245⟩
Nature, Nature Publishing Group, 2015, 519 (7542), pp.199-202. ⟨10.1038/nature14245⟩
Nature, 2015, 519 (7542), pp.199-202. ⟨10.1038/nature14245⟩
Nature, Nature Publishing Group, 2015, 519 (7542), pp.199-202. ⟨10.1038/nature14245⟩
International audience; Clustered regularly interspaced short palindromic repeat (CRISPR) loci and their associated (Cas) proteins provide adaptive immunity against viral infection in prokaryotes. Upon infection, short phage sequences known as spacer
Autor:
Lenden Hasse, Hélène, Lescale, Chloé, Bianchi, Joy, Yu, Wei, Bedora-Faure, Marie, Deriano, Ludovic
Publikováno v:
Journal of Immunological Methods
Journal of Immunological Methods, Elsevier, 2017, 451, pp.71-77. ⟨10.1016/j.jim.2017.08.007⟩
Journal of Immunological Methods, 2017, 451, pp.71-77. ⟨10.1016/j.jim.2017.08.007⟩
Journal of Immunological Methods, Elsevier, 2017, 451, pp.71-77. ⟨10.1016/j.jim.2017.08.007⟩
Journal of Immunological Methods, 2017, 451, pp.71-77. ⟨10.1016/j.jim.2017.08.007⟩
International audience; Antigen receptor gene assembly is accomplished in developing lymphocytes by the V(D)J recombination reaction, which can be separated into two steps: DNA cleavage by the recombination-activating gene (RAG) nuclease and joining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e4dd926b4108c0406ce78aed8afe218f
https://hal-pasteur.archives-ouvertes.fr/pasteur-03271165/file/1-s2.0-S0022175917303447-main.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03271165/file/1-s2.0-S0022175917303447-main.pdf
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.2714-2723. ⟨10.1093/nar/gkw1309⟩
Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.2714-2723. ⟨10.1093/nar/gkw1309⟩
International audience; Prokaryotic adaptive immunity relies on the capture of fragments of invader DNA (protospacers) followed by their recombination at a dedicated acceptor DNA locus. This integrative mechanism, called adaptation, needs both Cas1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b04918c8d792275773b9db6629f7fc5
https://hal-polytechnique.archives-ouvertes.fr/hal-01961608/document
https://hal-polytechnique.archives-ouvertes.fr/hal-01961608/document
Recent Mobility of Casposons, Self-Synthesizing Transposons at the Origin of the CRISPR-Cas Immunity
Publikováno v:
Genome Biology and Evolution
Genome Biology and Evolution, 2016, 8 (2), pp.375-86. ⟨10.1093/gbe/evw006⟩
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2016, 8 (2), pp.375-86. ⟨10.1093/gbe/evw006⟩
Genome Biology and Evolution, 2016, 8 (2), pp.375-86. ⟨10.1093/gbe/evw006⟩
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2016, 8 (2), pp.375-86. ⟨10.1093/gbe/evw006⟩
International audience; Casposons are a superfamily of putative self-synthesizing transposable elements that are predicted to employ a homolog of Cas1 protein as a recombinase and could have contributed to the origin of the CRISPR-Cas adaptive immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f1964b3f212be0e830b5054b6e11dd
https://hal.science/hal-01443928
https://hal.science/hal-01443928
Autor:
Elizabeth L. Qian, Tanya Labonne, Koula Sourris, Freya Bruveris, Ritu Chaurasia, Arash Rafii, David A. Anderson, Jacqueline V. Schiesser, Tim Kao, Andrew G. Elefanty, Zerina Lokmic, Clare L. Parish, Michael Cheung, Shireen R. Lamandé, Ali Motazedian, Antonietta Giudice, Magdaline Costa, Lachlan H. Thomson, Sara E. Howden, Peter G. Farlie, Elizabeth Ng, Anthony J. Penington, Edouard G. Stanley, David A. Elliott, Jonathan C. Niclis
Publikováno v:
Current Stem Cell Reports
Current Stem Cell Reports, Springer, 2016, 7 (3), pp.518-526. ⟨10.1016/j.stemcr.2016.07.015⟩
Stem Cell Reports, Vol 7, Iss 3, Pp 518-526 (2016)
Stem Cell Reports
Web of Science
Current Stem Cell Reports, Springer, 2016, 7 (3), pp.518-526. ⟨10.1016/j.stemcr.2016.07.015⟩
Stem Cell Reports, Vol 7, Iss 3, Pp 518-526 (2016)
Stem Cell Reports
Web of Science
Summary The ability to reliably express fluorescent reporters or other genes of interest is important for using human pluripotent stem cells (hPSCs) as a platform for investigating cell fates and gene function. We describe a simple expression system,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fbd96e72606a86a26e4273eac16d56
https://hal.umontpellier.fr/hal-03127126/document
https://hal.umontpellier.fr/hal-03127126/document