Výsledky vyhledávání - "MESH: Chitin Synthase"

Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion

Autor: Muszkieta, Laetitia, Aimanianda, Vishukumar, Mellado, Emilia, Gribaldo, Simonetta, Alcazar-Fuoli, Laura, Szewczyk, Edyta, Prevost, Marie-Christine, Latgé, Jean-Paul

Publikováno v: Cellular Microbiology
Cellular Microbiology, Wiley, 2014, 16 (12), pp.1784-1805. ⟨10.1111/cmi.12326⟩
Cellular Microbiology, 2014, 16 (12), pp.1784-1805. ⟨10.1111/cmi.12326⟩

International audience; Although chitin is an essential component of the fungal cell wall (CW), its biosynthesis and role in virulence is poorly understood. In Aspergillus fumigatus, there are eight chitin synthase (CHS) genes belonging to two famili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::88bf1542bb2388ddc5e6646f910a9aed
https://hal-pasteur.archives-ouvertes.fr/pasteur-02445787

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One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation

Autor: Oliver Bader, Martin Schaller, Ilse D. Jacobsen, Bernhard Hube, Adela Enache-Angoulvant, Daniel Fischer, Nadja Jablonowski, Sascha Brunke, Lydia Kasper, Katja Seider, Anja Wartenberg, Christophe d'Enfert

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478⟩
PLoS Pathogens, Public Library of Science, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478.s014⟩
Plos Pathogens 10 (10), . (2014)
PLoS Pathogens, Public Library of Science, 2014, 10 (10), ⟨10.1371/journal.ppat.1004478⟩
PLoS Pathogens, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478.s014⟩
PLoS Pathogens, Vol 10, Iss 10, p e1004478 (2014)

Candida glabrata is one of the most common causes of candidemia, a life-threatening, systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major factors contributing to the success of this opportunistic pathogen include i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c9d5496f487fe97c41f396b3a040f0
https://hal.inrae.fr/hal-02631278/file/brunke_2014_1.pdf

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Chitin Synthases with a Myosin Motor-Like Domain Control the Resistance of Aspergillus fumigatus to Echinocandins

Autor: Vishukumar Aimanianda, Isabelle Mouyna, Yves F. Dufrêne, Laetitia Muszkieta, Anne Beauvais, Sven Krappmann, Jean-Paul Latgé, Rémi Beau, David Alsteens, Cesar Roncero, Cristina Jiménez-Ortigosa, Stéphane Pire

Publikováno v: Antimicrobial Agents and Chemotherapy, Vol. 56, no.12, p. 6121-6131 (2012)
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2012, 56 (12), pp.6121-6131. ⟨10.1128/AAC.00752-12⟩
Antimicrobial Agents and Chemotherapy, 2012, 56 (12), pp.6121-6131. ⟨10.1128/AAC.00752-12⟩

Aspergillus fumigatus has two chitin synthases ( CSMA and CSMB ) with a myosin motor-like domain (MMD) arranged in a head-to-head configuration. To understand the function of these chitin synthases, single and double csm mutant strains were construct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3c7144acc4a4610dd1f3cd32b4c42
https://hdl.handle.net/2078/119971

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Disruption of the Bcchs3a chitin synthase gene in Botrytis cinerea is responsible for altered adhesion and overstimulation of host plant immunity

Autor: Caroline Kunz, Loïc Desquilbet, Delphine Arbelet, Thierry Fontaine, Marie-Christine Soulié, Pierrette Malfatti, Elizabeth Simond-Côte, Dominique Expert

Publikováno v: Molecular Plant-Microbe Interactions
Molecular Plant-Microbe Interactions, 2010, 23 (10), pp.1324-1334. ⟨10.1094/MPMI-02-10-0046⟩
Molecular Plant-Microbe Interactions, American Phytopathological Society, 2010, 23 (10), pp.1324-1334. ⟨10.1094/MPMI-02-10-0046⟩

International audience; The fungal cell wall is a dynamic structure that protects the cell from different environmental stresses suggesting that wall synthesizing enzymes are of great importance for fungal virulence. Previously, we reported the isola

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0eac5551348562ac0c2a3718b0e5642
https://hal-pasteur.archives-ouvertes.fr/pasteur-01719950

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Cell wall polysaccharide synthases are located in detergent-resistant membrane microdomains in oomycetes

Autor: Laurence Bessueille, Anne Briolay, Michel Guichardant, Nicolas Sindt, Christian Deshayes, Vincent Bulone, Jamel Bouzenzana

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2009, 75 (7), pp.1938-49. ⟨10.1128/AEM.02728-08⟩

The pathways responsible for cell wall polysaccharide biosynthesis are vital in eukaryotic microorganisms. The corresponding synthases are potential targets of inhibitors such as fungicides. Despite their fundamental and economical importance, most p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e997baeed815673693579865fe675b
https://hal.archives-ouvertes.fr/hal-00631309

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