Výsledky vyhledávání - "MESH: Chemotaxis, Leukocyte"

Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals

Autor: Guillaume Martin-Blondel, Jacques Izopet, Mary Requena, Bertrand Suc, Laurent Alric, Manon Nayrac, Nicolas Carrere, Pierre Delobel, Karl Barange, Claire Loiseau, Michelle Cazabat

Publikováno v: Mucosal Immunology
Mucosal Immunology, 2020, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (1), pp.219-228. ⟨10.1038/s41385-020-0286-6⟩

International audience; Gut CD4+ T cells are incompletely restored in most HIV-1-infected individuals on antiretroviral therapy, notably Th17 cells, a key subset in mucosal homeostasis. By contrast, gut Th22 cells are usually restored at normal frequ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7063cc54ac3d26c97d0c23435a80444c
https://ut3-toulouseinp.hal.science/hal-03157449

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Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages

Autor: Dimitri Pirottin, Sabine Olivier, Florent Ginhoux, Laurent Gillet, Fabrice Bureau, Cláudia A Fernandes, Geneviève Paulissen, Catherine Sabatel, Didier Cataldo, Coraline Radermecker, Thomas Marichal, Pascale Quatresooz, Svetoslav Chakarov, Xue Xiao, Christophe Desmet, Jean-Claude Sirard, Laurence Fievez, Marie Toussaint, Hicham Bouabe

Publikováno v: Immunity
Immunity, 2017, 46 (3), pp.457-473. ⟨10.1016/j.immuni.2017.02.016⟩
Immunity, Elsevier, 2017, 46 (3), pp.457-473. ⟨10.1016/j.immuni.2017.02.016⟩

International audience; Living in a microbe-rich environment reduces the risk of developing asthma. Exposure of humans or mice to unmethylated CpG DNA (CpG) from bacteria reproduces these protective effects, suggesting a major contribution of CpG to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83acdec0e916633bde247618da9c9110
https://doi.org/10.1016/j.immuni.2017.02.016

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TUMOR NECROSIS FACTOR IS NOT ASSOCIATED WITH INTESTINAL ISCHEMIA/REPERFUSION-INDUCED LUNG INFLAMMATION

Autor: Fernando Rodrigues Coelho, Lily Li, Jian Li, Rodrigo Guabiraba, Bernhard Ryffel, B. Boris Vargaftig, Wothan Tavares-de-Lima, Alexandre Learth Soares, Mamdouh A. Kamal

Publikováno v: Shock
Shock, 2010, 34 (3), pp.306-313. ⟨10.1097/SHK.0b013e3181cdc585⟩
Shock, Lippincott, Williams & Wilkins, 2010, 34 (3), pp.306-313. ⟨10.1097/SHK.0b013e3181cdc585⟩

Soares, Alexandre Learth Coelho, Fernando Rodrigues Guabiraba, Rodrigo Kamal, Mamdouh Vargaftig, B Boris Li, Lily Li, Jian Tavares-de-Lima, Wothan Ryffel, Bernhard Augusta, Ga. Shock. 2010 Sep;34(3):306-13. doi: 10.1097/SHK.0b013e3181cdc585.; Interna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7d9191bbd2dc4e2e70faa35c462574
https://doi.org/10.1097/shk.0b013e3181cdc585

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Role of β7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease

Autor: Konstantinos A. Papadakis, Werner Müller, Maria Apostolaki, Manolis Roulis, Marc–André Wurbel, George Kollias, Menelaos Manoloukos, Bernard Malissen, Dimitris L. Kontoyiannis

Publikováno v: Gastroenterology
Gastroenterology, WB Saunders, 2008, 134 (7), pp.2025-35. ⟨10.1053/j.gastro.2008.02.085⟩
Gastroenterology, 2008, 134 (7), pp.2025-35. ⟨10.1053/j.gastro.2008.02.085⟩

International audience; BACKGROUND & AIMS: In the present work, we address the requirement for intestinal-specific homing molecules, the chemokine/chemokine receptor pair CCL25/CCR9 and beta7 integrin, in the pathogenesis of the CD8(+) T cell-depende

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccde4e10e5d5180a1f3aeb9538627584
https://doi.org/10.1053/j.gastro.2008.02.085

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Protease-activated receptor 1 knockout reduces experimentally induced liver fibrosis

Autor: Anne Rullier, Nathalie Dugot-Senant, Jean Rosenbaum, Jennifer Gillibert-Duplantier, Gérard Déléris, Cyril Petibois, Pierre Costet, Gaelle Cubel, Valérie Haurie, Paulette Bioulac-Sage, Danièle Taras

Publikováno v: AJP-Gastrointestinal and Liver Physiology
AJP-Gastrointestinal and Liver Physiology, 2008, 294 (1), pp.G226-35. ⟨10.1152/ajpgi.00444.2007⟩

Thrombin inhibition protects against liver fibrosis. However, it is not known whether the thrombin profibrogenic effect is due to effects on blood coagulation or to signaling via protease-activated receptors (PARs). We took advantage of the lack of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43669519b81c8d6853c718c7987ecf
https://doi.org/10.1152/ajpgi.00444.2007

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Mucosal-associated invariant T cell–rich congenic mouse strain allows functional evaluation

Autor: Lionel Le Bourhis, Olivier Lantz, Yue Cui, Katarzyna Franciszkiewicz, Yvonne K. Mburu, Sylvie Rabot, Alexandra Kachaner, Emmanuel Martin, Claire Soudais, Stanislas Mondot, Virginie Premel, Livine Duban, Jean Jaubert, Molly A. Ingersoll, Jean-Pierre de Villartay

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
www.jci.org
Journal of Clinical Investigation, American Society for Clinical Investigation, 2015, 125 (11), pp.4171-4185. ⟨10.1172/JCI82424⟩
Journal of Clinical Investigation 11 (125), 4171-4185. (2015)

Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary conservation of the invariant TCR-alpha chain and restricting molecule MR1, this population is r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644f41ebbc4f1764869f11e52b9386a8
https://hal-pasteur.archives-ouvertes.fr/pasteur-01662502/file/JCI82424.pdf

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Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone

Autor: Marc Bajénoff, Ronald N. Germain, Nicolas Glaichenhaus

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (6), pp.3947-54

Although a great deal is known about T cell entry into lymph nodes, much less is understood about how T lymphocytes access the splenic white pulp (WP). We show in this study that, as recently described for lymph nodes, fibroblastic reticular cells (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9659527baa6a37bce8c5dbaa9bb9ba7b
https://hal.archives-ouvertes.fr/hal-00419277

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FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase

Autor: Christine Denoyelle, Nicolas Cagnard, Vladimir Lazar, Anne Dubart-Kupperschmitt, Georges Bismuth, Stéphanie Fabre, Florent Carrette, David A. Fruman, Marianne Mangeney, Valérie Lang, Jing Chen, Monique Semichon

In T cells, the PI3K pathway promotes proliferation and survival induced by Ag or growth factors, in part by inactivating the FOXO transcription factor 1. We now report that FOXO1 controls the expression of L-selectin, an essential homing molecule, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce312e1c799476d1405832208bbafe19
https://pubmed.ncbi.nlm.nih.gov/18713968

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Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

Autor: Ronald N. Germain, Frédéric Brau, Nicolas Glaichenhaus, Jackson G. Egen, Lily Koo, Marc Bajénoff, Jean Pierre Laugier

Publikováno v: Immunity
Immunity, Elsevier, 2006, 25 (6), pp.989-1001. 〈10.1016/j.immuni.2006.10.011〉
Immunity, Elsevier, 2006, 25 (6), pp.989-1001. ⟨10.1016/j.immuni.2006.10.011⟩

SummaryAfter entry into lymph nodes (LNs), B cells migrate to follicles, whereas T cells remain in the paracortex, with each lymphocyte type showing apparently random migration within these distinct areas. Other than chemokines, the factors contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c624438eeb8152c30c8e4e89baf7f4
https://hal.archives-ouvertes.fr/hal-00316442

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A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation

Autor: Jean-Baptiste Michel, Emilie Groyer, Giuseppina Caligiuri, Antonino Nicoletti, Kevin Guedj, Srini V. Kaveri, Jamila Khallou-Laschet, Alain Tedgui, Marc Clement, Giulia Fornasa, Anh Thu Gaston, Marion Morvan

Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2012, 94 (1), pp.30-7. ⟨10.1093/cvr/cvs076⟩
Cardiovascular Research, 2012, 94 (1), pp.30-7. ⟨10.1093/cvr/cvs076⟩
Cardiovascular Research; Vol 94

International audience; AIMS: The loss of the inhibitory receptor CD31 on peripheral T lymphocytes is associated with the incidence of atherosclerotic complications such as abdominal aortic aneurysms (AAA) in patients and plaque thrombosis in mice. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70daa3367b6352d84e9b7b95412cff56
https://www.hal.inserm.fr/inserm-00676680/document

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