High proportion of PD-1-expressing CD4 + T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence

Autor: Guillaume Pourcher, Abderaouf Damouche, Benoit Favier, Jean Jacques Lataillade, Bruno Vaslin, Valérie Pourcher, Christine Bourgeois, Elodie Busson, Olivier Lambotte, Mélanie Le Van, Stéphane Benoist, Thierry Lazure, Julien Adam, Michaela Müller-Trutwin

Publikováno v: European Journal of Immunology
European Journal of Immunology, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩
European Journal of Immunology, Wiley-VCH Verlag, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩

We and others have demonstrated that adipose tissue is a reservoir for HIV. Evaluation of the mechanisms responsible for viral persistence may lead to ways of reducing these reservoirs. Here, we evaluated the immune characteristics of adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca3eda57bdcf8b871126b640f92b28
https://doi.org/10.1002/eji.201747060