Clinical relevance of cell-free DNA quantification and qualification during the first month after lung transplantation

Autor: Pascal Pedini, Benjamin Coiffard, Nicem Cherouat, Sylvia Casas, Frédéric Fina, Audrey Boutonnet, Jean Baptiste Baudey, Printil Aho, Agnes Basire, Sophie Simon, Coralie Frassati, Jacques Chiaroni, Martine Reynaud-Gaubert, Christophe Picard

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 2023, 14, pp.1183949. ⟨10.3389/fimmu.2023.1183949⟩

BackgroundMany studies have reported the relevance of donor-derived cfDNA (dd-cfDNA) after lung transplantation (LTx) to diagnose and monitor acute rejection (AR) or chronic rejection or infection (INF). However, the analysis of cfDNA fragment size h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9ccc8afc307726208af65355d69470
https://hal.science/hal-04102417

Liquid biopsy and minimal residual disease — latest advances and implications for cure

Autor: Klaus Pantel, Catherine Alix-Panabières

Publikováno v: Nature Reviews Clinical Oncology
Nature Reviews Clinical Oncology, Nature Publishing Group, 2019, 16 (7), pp.409-424. ⟨10.1038/s41571-019-0187-3⟩

Liquid biopsy has been introduced as a new diagnostic concept predicated on the analysis of circulating tumour cells (CTCs) or circulating tumour-derived factors, in particular, cell-free tumour DNA (ctDNA). Highly sensitive liquid biopsy assays have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8152abcae409d0e9098ef6ce5732c30
https://doi.org/10.1038/s41571-019-0187-3

Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma

Autor: Aubin Béré, Pascal Pineau, Paul Jean Adrien Atangana, Dominique Noah Noah, Claudine Bekondi, Narcisse-Patrice Komas, Marie Amougou Atsama, Agnès Marchio, Richard Njouom, Serge-Magloire Camengo-Police

Publikováno v: Clinical and Experimental Medicine
Clinical and Experimental Medicine, Springer Verlag, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩
Clinical and Experimental Medicine, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩

International audience; Hepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa. Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this situation. The role of aflatoxin in HCC from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0243714b8db486523f54ee36267f9f89
https://hal-pasteur.archives-ouvertes.fr/pasteur-02611946/file/Marchio2018_Article_DropletDigitalPCRDetectsHighRa.pdf